Training Program in Marine Biotechnology

描述(由申请者提供)：这一修订后的培训计划申请将为学生提供一个在海洋生物技术组成领域的跨学科教育和研究培训的特殊机会，包括天然产品化学、生物化学、基因组学、药理学和医学。此外，这笔培训补助金将通过在加州大学圣地亚哥分校校园内多个系的不同实验室以及索尔克研究所和J·克雷格·文特尔研究所培训个别学生，提供协作的跨学科研究指导。为了完成这一使命，TP有以下目标：(1)提供新的课程，在加州大学圣迭戈分校校园内创建独特的课程，这是多学科海洋生物技术领域研究的智力基础(2)提供由海洋生物技术领域的领导者举办的一系列激动人心的研讨会，并通过安排和接待这些来访演讲者的特殊机会培养学员的技能(3)提供行业实习，拓宽毕业生的教育基础和技术视角(4)为我们的学员提供机会，通过年度研讨会、参加各种研究和期刊俱乐部来发展他们的研究陈述技能，以及参加国家和国际会议(5)，向特别优秀的受训人员提供为期两年的有竞争力的财政支助，以表彰他们出色的研究努力和才华。这一培训计划的基本原理是，需要为生物技术行业和学术界培训学生，使他们具备海洋系统及其独特的化学、生化和遗传属性的综合知识。据我们所知，这一广泛的培训平台是美国任何其他机构都没有的，因此我们的毕业生受到欢迎，以满足工业界和学术界的独特需求。该培训计划在续期的前两年为6名博士前实习生，在后三年为8名博士前实习生，并辅之以2名或更多大学支持的实习生，以支持学生完成5年制博士课程的第二年和第三年。在海洋生物技术TP的支持下，这些教职员工和研究力量正在帮助加州大学圣迭戈分校创建一个独特的、国际公认的教育和研究项目。 相关性：海洋生物是一种特殊的天然产品来源，具有有用的医疗特性。综合的化学和遗传方法加强了充分利用这些天然产品的能力，这种方法本身就很复杂，而且是多学科的。加州大学圣迭戈分校拥有一套独特的学术和研究项目，可以在这些领域培养下一代科学家。

DESCRIPTION (provided by applicant): This revised Training Program application will provide students with an exceptional opportunity for cross disciplinary education and research training in the component areas of marine biotechnology, including natural products chemistry, biochemistry, genomics, pharmacology, and medicine. Moreover, this training grant will provide collaborative cross-disciplinary research mentorship through training individual students in different laboratories in multiple departments on the UCSD campus as well as the Salk Institute and J. Craig Venter Institute. To accomplish this mission, the TP has the following objectives: (1) to provide new course offerings that create a unique curriculum on the UCSD campus that is the intellectual foundation for research in the multidisciplinary field of Marine Biotechnology (2) to provide a stimulating series of seminars by leaders in the field of Marine Biotechnology, and to develop skills in our trainees through special opportunities to arrange and host these visiting speakers (3) to provide Industrial Internships that broaden the educational base and technology perspective of our graduates (4) to provide opportunities to our trainees that develop their research presentation skills through an annual symposium, participation in various research and journal clubs, and participation at national and international conferences (5) to provide competitively awarded financial support to especially meritorious trainees for a 2-year period in recognition of their superior research efforts and talents. The rationale for this training program is the need to train students for the biotechnology industry as well as for academia with an integrated knowledge of marine systems and their unique chemical, biochemical, and genetic attributes. To our knowledge, this broad training platform is not offered at any other institution in the US, and thus our graduates are sought after to fill a unique need in industry and academia. The training is proposed for 6 predoctoral trainees in the first two years and 8 predoctoral trainees in the latter three years of the renewal period, supplemented by 2 or more university-supported trainees, to support students in their second and third year of their 5-year Ph.D. programs. The assembly of this faculty and research strength under the auspices of the TP in Marine Biotechnology is helping to create a unique, internationally recognized educational and research program at UCSD. RELEVANCE: Marine organisms are an exceptional source of natural products with useful medical properties. Fully accessing these natural products is enhanced by an integrated chemical and genetic approach, which is inherently complex and multidisciplinary. UCSD has a unique assembly of academic and research programs which can train the next generation of scientists in these areas.