Fiber-based time-lens synchronized source for coherent Raman scattering microscop

用于相干拉曼散射显微镜的光纤时间透镜同步源

• 批准号: 8496835
• 负责人: CHRIS XU
• 金额: $ 18.88万
• 依托单位: CORNELL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-01 至 2014-08-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8496835
• 关键词: Amides; Area; Biomedical Research; Clinical; Development; Diagnostic; Electronics; Environment; Feedback; Fiber; Frequencies; Generations; Goals; Image; Industry; Lasers; Mechanics; Medical; Microscope; Microscopy; Modification; Optics; Output; Physiologic pulse; Printing; Process; Radio; Relative (related person); Research; Research Personnel; Safety; Scanning; Source; Stretching; System; Systems Integration; Techniques; Technology; Telecommunications; Testing; Time; Width; base; cost; design; foot; innovation; lens; lithium niobate; novel; operation; programs; research study; second harmonic; time use

DESCRIPTION (provided by applicant): The goal of this research program is to develop a novel fiber-based source for coherent Raman scattering (CRS) microscopy. We will develop a fiber-based picosecond source tunable from 800 nm to 910 nm and an all-fiber time-lens synchronized source at 1064 nm, and then demonstrate the value of the proposed laser system for CRS microscopy. The proposed source is based on two major innovations: (1) soliton self-frequency shift (SSFS) in a large mode area (LMA) fiber that enables the generation of energetic, wavelength tunable soliton pulses seeded by a fiber laser at the telecom wavelength (~ 1550 nm), and (2) time-lens pulse compression and synchronization that enables an all-fiber picosecond source to synchronize to a mode- locked laser at arbitrary repetition rate. Leveraging the highly mature and integrated techniques that have been developed for the telecommunications industry, we aim to create a "telecom grade" synchronized source that is truly robust and turn-key, and tailored specifically for biomedical research and clinical diagnostics. The successful completion of this program will facilitate the widespread applications of CRS imaging in biomedical research.

描述（由申请人提供）：本研究项目的目标是开发一种新的基于光纤的相干拉曼散射（CRS）显微镜光源。我们将开发800 ~ 910 nm的光纤皮秒源和1064 nm的全光纤时透镜同步源，然后证明所提出的激光系统在CRS显微镜中的价值。提出的光源基于两个主要创新：(1)大模区（LMA）光纤中的孤子自频移（SSFS），使光纤激光器能够在电信波长（~ 1550 nm）产生能量，波长可调的孤子脉冲；(2)时间透镜脉冲压缩和同步，使全光纤皮秒源能够以任意重复率同步到锁模激光器。利用为电信行业开发的高度成熟和集成的技术，我们的目标是创建一个真正强大和交钥匙的“电信级”同步源，专门为生物医学研究和临床诊断量身定制。该项目的成功完成将促进CRS成像在生物医学研究中的广泛应用。