EPIDEMIOLOGY AND CANCER CONTROL

项目总结(见说明)； 流行病学和癌症控制计划由来自12个部门的34名调查人员(30名正式成员和4名准成员)组成。该计划的总体使命是降低癌症发生和死亡的风险，并提高癌症幸存者的生活质量。为了完成这一使命，它有四个主要的科学目标：1)确定癌症的环境和遗传决定因素，以改进癌症预防手段，特别是侧重于了解环境因素在癌症病因学中的作用，确定癌症病因学中的代谢和生殖因素，了解人类遗传学在癌症病因和进展中的作用，以及确定与人类微生物群有关的癌症风险；2)通过风险因素修改来减少癌症负担，特别是肥胖控制和减少烟草使用；3)通过及早发现癌症来减轻癌症负担，特别注重应用各种方法，增加未得到充分服务的人群的筛查参与率，并开发新的早期检测生物标记物；以及4)解决患者和幸存者与癌症有关的负担，特别强调满足未得到充分服务的人的需求。研究的重点领域是 跨学科，包括来自ECC和其他纽约大学癌症研究所研究项目的人口、实验室和临床科学家。理查德·海斯博士和布莱恩·施密特博士是该项目的联合负责人。 这是一个新项目，目前有16,940,943美元的资金。这一期间的出版物共计216份，其中17.6%是方案内出版物，11.1%是方案间出版物，8.8%是方案内和方案间合作出版物。

PROJECT SUMMARY (See instructions); The Epidemiology & Cancer Control Program is composed of 34 investigators (30 Full and 4 Associate members) from 12 Departments. The overall mission of the Program is to reduce the risk of cancer occurrence and death and to enhance the quality of life of cancer survivors. To fulfill this mission, it has 4 major scientific objectives: 1) To identify environmental and genetic determinants of cancer to improve means of cancer prevention, focusing specifically on understanding the role of environmental factors in cancer etiology, determining the metabolic and reproductive factors in cancer etiology, understanding the role of human genetics in cancer etiology and progression, and identifying cancer risks associated with the human microbiome; 2) To reduce cancer burden by risk factor modification, with a specific focus on obesity control and tobacco use reduction; 3) To reduce cancer burden by early detection of cancer, with a specific focus on the application of methods to increase screening participation by underserved populations and the development of novel early detection biomarkers; and 4) To address cancer-related burden in patients and survivors, with a particular emphasis on meeting the needs of the underserved. The research focus areas are interdisciplinary, including population, laboratory and clinical scientists from ECC and other NYU CancerInstitute Research Programs. Drs. Richard Hayes and Brian Schmidt are the Co-Leaders for this Program. This is a new Program that currently has $16,940,943 on funding. Publications for the period total 216, of which 17.6% are intra-programmatic, 11.1% are inter-programmatic, and 8.8% are both intra- and interprogrammatic collaborations.