EPIDEMIOLOGY AND CANCER CONTROL

项目总结（见说明）; 流行病学和癌症控制方案由来自12个部门的34名调查员（30名正式成员和4名准成员）组成。该方案的总体使命是降低癌症发生和死亡的风险，提高癌症幸存者的生活质量。为了完成这一使命，它有4个主要的科学目标：1）确定癌症的环境和遗传决定因素，以改善癌症预防的手段，特别关注了解环境因素在癌症病因中的作用，确定癌症病因中的代谢和生殖因素，了解人类遗传学在癌症病因和进展中的作用，2）通过改变风险因素来减少癌症负担，特别关注肥胖控制和减少烟草使用; 3）通过早期发现癌症来减少癌症负担，特别注重应用方法，增加服务不足人群的筛查参与率，并开发新的早期检测生物标志物;（4）解决癌症患者和幸存者的负担问题，特别注重满足服务不足者的需要。研究重点领域是 跨学科的，包括人口，实验室和临床科学家从ECC和其他纽约大学癌症研究所研究计划。Richard Hayes博士和Brian施密特博士是该项目的共同负责人。 这是一个新的方案，目前有16，940，943美元的资金。这一时期的出版物共计216种，其中17.6%是方案内的，11.1%是方案间的，8.8%是方案内和方案间的合作。

PROJECT SUMMARY (See instructions); The Epidemiology & Cancer Control Program is composed of 34 investigators (30 Full and 4 Associate members) from 12 Departments. The overall mission of the Program is to reduce the risk of cancer occurrence and death and to enhance the quality of life of cancer survivors. To fulfill this mission, it has 4 major scientific objectives: 1) To identify environmental and genetic determinants of cancer to improve means of cancer prevention, focusing specifically on understanding the role of environmental factors in cancer etiology, determining the metabolic and reproductive factors in cancer etiology, understanding the role of human genetics in cancer etiology and progression, and identifying cancer risks associated with the human microbiome; 2) To reduce cancer burden by risk factor modification, with a specific focus on obesity control and tobacco use reduction; 3) To reduce cancer burden by early detection of cancer, with a specific focus on the application of methods to increase screening participation by underserved populations and the development of novel early detection biomarkers; and 4) To address cancer-related burden in patients and survivors, with a particular emphasis on meeting the needs of the underserved. The research focus areas are interdisciplinary, including population, laboratory and clinical scientists from ECC and other NYU CancerInstitute Research Programs. Drs. Richard Hayes and Brian Schmidt are the Co-Leaders for this Program. This is a new Program that currently has $16,940,943 on funding. Publications for the period total 216, of which 17.6% are intra-programmatic, 11.1% are inter-programmatic, and 8.8% are both intra- and interprogrammatic collaborations.