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中文摘要
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实验病理学共享资源的总体目标是为NYUCI的研究人员提供质量可控、稳定和具有成本效益的服务和专业知识,用于人类和动物组织的显微分析。它分为两个实验室:1)组织病理学和2)免疫组织化学。组织病理学实验室提供常规的组织病理学服务,包括石蜡和冷冻包埋组织的组织准备、加工、包埋、切片和组织化学染色。组织病理学实验室还提供整个玻片数字成像和基本显微镜服务,并提供最先进的仪器,如激光显微解剖系统。免疫组织化学实验室的主要作用是为尚未在新鲜、冷冻或固定的人类或动物组织和细胞中进行测试的新抗体(商业或专利抗体)开发免疫组织化学方案。它也是一个免疫组织化学抗体库,有900多种商业和专利抗体的目录,并在实验室网站上公布。这两个实验室都为病理学和转化医学研究生培训计划提供一对一的培训和正式的教学模块,并为医学生提供微型轮换。实验病理学实验室的独特定位是
英文摘要
The overall objectives of the Experimental Pathology Shared Resource are to provide NYUCI investigators with quality-controlled, stable and cost-effective services and expertise for the microscopic analysis of human and animal tissues. It is divided into two laboratories: 1) Histopathology and 2) Immunohistochemistry. The Histopathology laboratory provides routine histopathologic services, including tissue preparation, processing, embedding, sectioning and histochemical staining for paraffin and cryoembedded tissues. The Histopathology laboratory also provides whole slide digital imaging and basic microscopy services, and it makes available state-of-the art instrumentation, such as a laser microdissection system. The main role of the Immunohistochemistry laboratory is to develop immunohistochemical protocols for new antibodies (commercial or proprietary) that have not been tested in fresh, frozen or fixed human or animal tissues and cells. It also serves as an immunohistochemical antibody repository with a catalog of over 900 commercial and proprietary antibodies, which is published on the laboratory website. Both laboratories offer one-on-one training as well as formal teaching modules for the Pathobiology and Translational Medicine Graduate Training program and mini-rotations for medical students. The Experimental Pathology laboratories are uniquely positioned as a
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Remodeling of 3D chromatin in B cell acute leukemia and its impact on clinical outcome
Remodeling of 3D chromatin in B cell acute leukemia and its impact on clinical outcome
Remodeling of 3D chromatin in B cell acute leukemia and its impact on clinical outcome
BIOMEDICAL INFORMATICS
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