EXPERIMENTAL PATHOLOGY

实验病理学

• 批准号: 8436442
• 负责人: William L. Carroll
• 金额: $ 7.03万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-03-01 至 2018-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8436442
• 关键词: Antibodies; Cancer Center Support Grant; Cataloging; Catalogs; Cells; Data; Educational process of instructing; Experimental Animal Model; Experimental Pathology; Faculty; Freezing; Histopathology; Immunohistochemistry; Institutes; Instruction; Journals; Kaplan Cancer Center; Laboratories; Lasers; Malignant Neoplasms; Medical Students; Microdissection; Microscopic; Microscopy; Mission; Paraffin; Play; Positioning Attribute; Principal Investigator; Process; Protocols documentation; Publications; Publishing; Quality Control; Research; Research Personnel; Resource Sharing; Role; Rotation; Services; Slide; Specimen; Staining method; Stains; System; Testing; Tissues; Training; Training Programs; animal tissue; cost effective; digital imaging; human tissue; instrumentation; repository; tissue preparation; translational medicine; web site

The overall objectives of the Experimental Pathology Shared Resource are to provide NYUCI investigators with quality-controlled, stable and cost-effective services and expertise for the microscopic analysis of human and animal tissues. It is divided into two laboratories: 1) Histopathology and 2) Immunohistochemistry. The Histopathology laboratory provides routine histopathologic services, including tissue preparation, processing, embedding, sectioning and histochemical staining for paraffin and cryoembedded tissues. The Histopathology laboratory also provides whole slide digital imaging and basic microscopy services, and it makes available state-of-the art instrumentation, such as a laser microdissection system. The main role of the Immunohistochemistry laboratory is to develop immunohistochemical protocols for new antibodies (commercial or proprietary) that have not been tested in fresh, frozen or fixed human or animal tissues and cells. It also serves as an immunohistochemical antibody repository with a catalog of over 900 commercial and proprietary antibodies, which is published on the laboratory website. Both laboratories offer one-on-one training as well as formal teaching modules for the Pathobiology and Translational Medicine Graduate Training program and mini-rotations for medical students. The Experimental Pathology laboratories are uniquely positioned as a

实验病理学共享资源的总体目标是为NYUCI研究人员提供质量可控，稳定和具有成本效益的服务和专业知识，用于人类和动物组织的显微镜分析。它分为两个实验室：1）组织学和2）免疫组织化学。组织病理学实验室提供常规组织病理学服务，包括石蜡和冷冻包埋组织的组织制备、处理、包埋、切片和组织化学染色。组织学实验室还提供全载玻片数字成像和基本显微镜服务，并提供最先进的仪器，如激光显微切割系统。免疫组织化学实验室的主要作用是为尚未在新鲜，冷冻或固定的人类或动物组织和细胞中测试的新抗体（商业或专有）制定免疫组织化学方案。它还作为免疫组织化学抗体库，拥有900多种商业和专有抗体的目录，并在实验室网站上发布。这两个实验室都提供一对一的培训以及病理生物学和转化医学研究生培训计划的正式教学模块和医学生的小型轮换。实验病理学实验室的独特定位是