RNAI

RNAI

• 批准号: 8436448
• 负责人: William L. Carroll
• 金额: $ 7.03万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-03-01 至 2018-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8436448
• 关键词: Agreement; Bioinformatics; Cancer Center Support Grant; Collaborations; Commit; Communities; Double-Stranded RNA; Genes; Genome; Human; Instruction; International; Libraries; Logistics; Medical center; Mus; RNA Interference; Research Personnel; Resource Sharing; Services; Small Interfering RNA; Testing; Universities; base; cost effective; fly; high throughput screening; screening; small molecule

PROJECT SUMMARY (See instructions): The RNAi Shared Resource provides an integrated, state-of-the-art, RNA interference (RNAi) based high throughput screening (HTS) facility at the NYU Langone Medical Center (NYULMC). The Shared Resource is committed to offering siRNA / dsRNA screening libraries for the cross-species functional characterization of whole genomes in a systematic, comprehensive, and cost effective manner. In addition, the facility may also provide logistic, technical, and bioinformatic support in order to assist screeners in performing and interpreting their genome scale RNAi screens. Importantly, the facility is strongly committed to making the NYU RNAi Shared Resource fully accessible to the entire academic community, both at the national and international level, in order to facilitate inter-disciplinary and multi-institutional collaborations.

项目总结(见说明)： RNAi共享资源在纽约大学朗格内医学中心(NYULMC)提供基于RNA干扰(RNAi)的集成、最先进的高通量筛查(HTS)设施。共享资源致力于以系统、全面和经济高效的方式提供siRNA/dsRNA筛选文库，用于整个基因组的跨物种功能表征。此外，该设施还可以提供后勤、技术和生物信息支持，以协助筛查员执行和 解释他们基因组规模的RNAi屏幕。重要的是，该机构坚定地致力于使纽约大学RNAi共享资源在国家和国际层面上完全可供整个学术界使用，以促进跨学科和多机构合作。