RESOURCE CORE 1: BIOSTATISTICS, INFORMATICS AND TRANSLATIONAL RESEARCH

资源核心 1：生物统计学、信息学和转化研究

• 批准号: 8513209
• 负责人: ANDREW P GOLDBERG
• 金额: $ 13.19万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-15 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8513209
• 关键词: Adverse event; American; Area; Attention; Bioinformatics; Biometry; Biostatistics Core; Calendar; Chronic Disease; Clinic; Clinical; Clinical Research; Clinical Research Curriculum Award; Collaborations; Communities; Confidentiality; Data; Data Analyses; Data Storage and Retrieval; Databases; Detection; Discipline; Elderly; Ensure; Environment; Epidemiology; Exercise; Faculty; Fostering; Funding; Gerontology; Goals; Informatics; Information Systems; Institution; Instruction; Interdisciplinary Study; Intervention; Investigation; Laboratories; Laboratory Study; Leadership; Maintenance; Management Information Systems; Maryland; Mentors; Metabolic; Methodology; Monitor; Motor; Obesity; Public Health; Publishing; Quality Control; Randomized; Recruitment Activity; Registries; Rehabilitation therapy; Reporting; Research; Research Design; Research Infrastructure; Research Personnel; Research Support; Resource Sharing; Resources; Risk; Robotics; Sample Size; Schedule; Scientist; Secure; Security; Series; Services; System; Training; Translational Research; Translations; Universities; Vertebral column; Work; base; data integrity; data management; design; didactic education; disability; functional decline; improved; lectures; member; nervous system disorder; nutrition; prevent; programs; research and development; research study; restoration; statistics; successful intervention; user-friendly; working group

The goal of the Biostatistics, Informatics, and Translational Research Core (RC-1) is to establish and an environment that promotes excellence in the design and execution of OAIC studies where best statistical practices guide the analysis of data, to facilitate the search for mechanisms underlying successful interventions, and to promote the translation of promising interventions into the clinic and community.The Core will organize Research Working Groups (RWGs) that will assist with the design, execution, and oversight of all University of Maryland Older Americans Independence Center's (OAIC) research, and will provide an informatics backbone, GERI, that will support all aspects of the Center's work. We will make sure that best statistical practices guide the design and execution of OAIC research, the analysis of data, and the interpretation of the results of the analysis. We will educate faculty, RCDC scholars Qr. faculty) and staff in the principles of statistics and epidemiology. Our Research Working Groups, composed of the study PI, the Pi's mentor (if the PI is an RCDC Scholar), and one member from each Core, will use the automated reports produced by GERI as they oversee the progress of OAIC studies and monitor study progress. The reports will support the RWGs' efforts to assure that OAIC studies are completed in a timely fashion, and will help the RWGs identify studies that have potential for translation from laboratory bench, to center-based studies, and to community-based interventions. GERI will collect and track requests for OAIC services (Request for Services System), will assist with the recruiting of subjects (Registry), will track study progress (Tracking Database), collect information regarding adverse events (Adverse Event Database), and will facilitate laboratory quality control (Quality Control and Outlier Detection Systems). Our educational efforts will include our lecture series as well as the formal didactic education provided by our institution's MPH program, our K30 program, which offers an MS in Clinical Research, and our summer course Clinical and Translational Research at UMB.

生物统计学，信息学和转化研究核心（RC-1）的目标是建立一个促进OAIC研究设计和执行的卓越环境，其中最佳统计实践指导数据分析，以促进寻找成功干预的机制，并促进将有前途的干预措施转化为临床和社区。核心将组织研究工作组（RWG）这将有助于设计，执行和监督所有的马里兰州大学老年美国人独立中心（OAIC）的研究，并将提供一个信息学骨干，GERI，这将支持该中心的工作的各个方面。我们将确保最佳统计实践指导OAIC研究的设计和执行，数据分析以及分析结果的解释。我们将教育教师，RCDC学者Qr。教师）和工作人员在统计学和流行病学的原则。 我们的研究工作组由研究PI、PI的导师（如果PI是RCDC学者）和每个核心的一名成员组成，将使用GERI生成的自动报告，监督OAIC研究的进展并监测研究进展。这些报告将支持RWG努力确保OAIC研究及时完成，并将帮助RWG确定 从实验室工作台到基于中心的研究以及基于社区的干预措施的转化潜力。GERI将收集和跟踪OAIC服务请求（服务请求系统），协助招募受试者（登记研究），跟踪研究进展（跟踪数据库），收集不良事件相关信息（不良事件数据库），并促进实验室质量控制（质量控制和离群值检测系统）。我们的教育工作也将包括我们的系列讲座 作为我们机构的MPH计划提供的正式教学教育，我们的K30计划提供临床研究硕士学位，以及我们在UMB的暑期课程临床和转化研究。