Salmonella in pets in GA

项目摘要/摘要 据估计，沙门氏菌导致140万人患病，导致16000人死亡 住院人数，美国每年有582人死亡。的发病率。 美国境内的沙门氏菌病在各州和各州都有所不同。这些差异 不能完全用人口密度、文化/种族的差异来解释 海关，或食品分销网络。这些疾病发病率的地区差异 也反映在沙门氏菌的血清型分布上。我们不知道或不了解 可能解释了沙门氏菌感染在美国部分地区的地理分布 答案在于确定替代储油层，例如宠物。更好地理解 沙门氏菌在宠物体内的传播动态将有助于我们了解沙门氏菌在 这些独特的伴生物，在沙门氏菌和人类的分布动态中 疾病。这项建议探讨了我们宠物的食物来源、它们的生活方式 人类文化、地理区域可能对沙门氏菌的分布产生影响 伴侣动物中的血清型和菌株，最终在人类散发性病例中 沙门氏菌病。我们建议通过培养有症状的和 无症状犬横跨GA。我们将确定沙门氏菌的流行情况 健康和生病的宠物。然后将对沙门氏菌血清型和菌株进行分型和分析 为了确定是否存在与宠物家的地理位置的任何关联， 他们的生活方式或我们调查问卷中出现的任何其他特征。

Project Summary/Abstract Salmonella accounts for an estimated 1.4 million illnesses, resulting in 16,000 hospitalizations, and 582 deaths in the United States each year. The incidence of salmonellosis within the U.S. differs from state to state and in state. These differences cannot be explained entirely by differences in population density, cultural/ethnic customs, or food-distribution networks. These regional differences in disease incidence are also reflected in Salmonella serovar distribution. We do not know or understand what might explain this geographic scattering of Salmonella infection in the U.S. Part of the answer lies in identifying alternate reservoirs, such as pets. A better understanding of the transmission dynamics of Salmonella in pets will helps us understand the role of these unique companions, in the distribution dynamics of Salmonella and human illnesses. This proposal explores the role that the food sources of our pets, their lifestyle, human culture, and geographic region may have on the distribution of Salmonella serovars and strains in companion animals and ultimately in cases of human sporadic salmonellosis. We propose to do this by culturing fecal samples from symptomatic and asymptomatic dogs across GA. We will determine prevalence of Salmonella both in healthy and sick pets. Salmonella serovars and strains will be then typed and analyzed to determine if any correlations exists which the geographical location of the pets home, their lifestyle or any other characteristic present in our questionnaire.