Capacity Development for Research into AIDS Associated malignancies (CADRE)

描述(由申请者提供)：尼日利亚艾滋病毒相关恶性疾病研究能力发展培训计划(Cadre-Nigia)旨在发展尼日利亚人类病毒学研究所(IHV-Nigia)及其学术研究伙伴的临床试验和癌症研究专业知识。本次研究培训实施四个目标：临床试验能力、癌症登记、癌症流行病学和综合研究能力建设。干部-尼日利亚将举办13期短期培训课程，41期中级培训，3名学员为期3年的深入远程培训。由福格蒂赞助的UM-IHV AITRP(D43 TW001041)开创的“导师-导师”培训战略是尼日利亚干部学院的基础，通过聘请一名国际教职导师、一名尼日利亚教职导师和一名更初级的教职或非教职实习生参加培训三位一体的培训，建立可持续的能力，在尼日利亚研究合作伙伴网站建立关键的调查人员队伍，并在国际和尼日利亚教职员工之间建立学术联系，以促进持续的研究合作。这次培训的主要成果是尼日利亚艾滋病恶性临床试验联合会(AMC-Nigia)在尼日利亚阿布贾的卓越中心，该中心实施了NCI资助的AMC临床试验和艾滋病毒-恶性肿瘤研究，并在尼日利亚其他地点作为从南到南与艾滋病毒相关的恶性肿瘤能力发展的国家培训中心。为了扩大艾滋病毒-恶性肿瘤检测、肿瘤登记和癌症流行病学培训，将利用IHV-尼日利亚的PEPFAR计划中的140,000名艾滋病毒护理人员，为AMC-尼日利亚NCI癌症标本资源网络试验和NIAID/NCI资助的西非国际流行病学数据库评估艾滋病(LeDEA)网络的癌症研究议程提供丰富的病例转介资源，这两个网络都与IHV-尼日利亚有关。GADRE-尼日利亚的预期影响是参与越来越多的流行病学和临床试验方案、改进癌症登记、艾滋病毒-癌症联系研究以及尼日利亚艾滋病相关癌症的管理。

DESCRIPTION (provided by applicant): The Capacity Development for Research into HIV-Associated Malignancies in Nigeria (CADRE-Nigeria) training program targets development of clinical trials and cancer research expertise at the Institute of Human Virology, Nigeria (IHV-Nigeria) and its academic research partners. This research training implements four aims: clinical trials capacity, cancer registration, cancer epidemiology and general research capacity building. CADRE-Nigeria will conduct 13 short-term training courses, intermediate training for 41, and in depth long-range training for 3 trainees over 3 years. CADRE-Nigeria is anchored by the "mentor-the-mentor" training strategy pioneered by the Fogarty-sponsored UM-IHV AITRP (D43 TW001041) that builds sustainable capacity by engaging an international faculty mentor, a Nigerian faculty mentor and a more junior faculty or non-faculty trainee in a training triad that builds a critical mass of investigative staff at the Nigerian research partner site and creates an academic bond between the international and Nigerian faculty to promote sustained research collaboration. The major outcome of this training is a Nigerian HIV-malignancy center of excellence the AIDS Malignancy Clinical Trials Consortium-Nigeria (AMC-Nigeria) site in Abuja, Nigeria that implements NCI funded AMC clinical trials, HIV-malignancy research and serves as a national training center for south to south HIV-associated malignancy capacity development at other sites in Nigeria. To expand HIV-malignancy detection tumor registration and cancer epidemiology training will exploit the 140,000 in HIV care in IHV-Nigeria's PEPFAR program providing a rich resource for case referral for the AMC-Nigeria trials for NCI Cancer Specimen Resource networks and the cancer research agenda of the NIAID/NCI-funded West Africa International Epidemiologic Database to Evaluate AIDS (leDEA) network both linked to IHV-Nigeria. The expected impact of CADRE-Nigeria is participation in an increasing number of epidemiology and clinical trials protocols, improvement in cancer registration, HIV-Cancer linkage studies and management of AIDS Associated Cancers in Nigeria.