Training Program in Hematology

描述（由申请人提供）：血液学学科仍然是将免疫学，分子生物学和细胞生物学中的基础科学发现转化为人类有前途的新疗法的典范。为了最大限度地利用我们的机会，将新生的科学知识转化为临床血液学，我们需要永久的天才和训练有素的医生科学家谁将实验室和诊所之间的翻译池。为了将基础科学与临床研究充分联系起来，受训者必须在激励和培养研究环境中接受严格的实验室培训和强有力的指导。不幸的是，在血液学学科中缺乏受过这种培训的年轻研究人员。最近对美国和加拿大成人和儿科血液学/肿瘤学亚专业培训项目负责人的调查发现，接受学术血液学培训的研究员存在不足（1）。该研究指出，“令人关切的是，选择血液学单板资格（100/o）并从事非恶性血液学职业的受训者人数很少（成人培训课程毕业生的6%）。“约翰霍普金斯的血液学系是美国为数不多的独立血液学系之一。因此，拟议的培训计划的目的是准备合格的个人与医学博士。和/或博士在血液学领域的研究生涯的学位。该计划为血液学研究培训提供跨学科的实验室培训，为血液学研究全职职业的个人做准备。受训人员在主要研究人员的实验室从事与良性和恶性血液疾病生物学有关的项目。这些研究项目，在课程工作，研究研讨会，期刊俱乐部，实验室会议，并出席国家和国际会议的参与，提供学员的基本知识和所需的技能，成功地作为独立的调查。

DESCRIPTION (provided by applicant): The discipline of Hematology continues to be a model for translating basic scientific discoveries in immunology, molecular biology, and cellular biology into promising new therapies for human beings. To maximize our opportunity to translate nascent scientific knowledge into clinical hematology, we need to perpetuate the pool of gifted and highly trained physician-scientists who will translate between the laboratory and the clinic. To fully link basic science with clinical investigation, a trainee must receive rigorous laboratory training and strong mentoring in a stimulating and nurturing research environment. Unfortunately, there is a shortage of young investigators with such training in the discipline of hematology. A recent survey of directors of adult and pediatric hematology/oncology subspecialty training programs in the United States and Canada found a deficiency in fellows trained in academic Hematology (1). The study stated that, "Concern is raised over the small numbers of trainees who opt for single-board eligibility in Hematology (100/o) and pursue careers in nonmalignant Hematology (<6% of graduates of adult training programs)." The Division of Hematology at Johns Hopkins is one of the few remaining free-standing Hematology Programs in the country. Thus, the purpose ofthe proposed training program is to prepare qualified individuals with an M.D. and/or Ph.D. degree for a research career in the field of Hematology. This program for research training in hematology provides interdisciplinary laboratory training for individuals preparing for full-time careers in hematology research. Trainees work on projects relevant to the biology of benign and malignant blood disorders in the laboratories of leading investigators. These research projects, in conjunction with participation in course-work, research seminars, journal clubs, laboratory meetings, and attendance at National and International meetings, afford trainees the basic knowledge and required skills to function successfully as independent investigators.