Training Program in Hematology

项目摘要/摘要 血液学培训计划的主要目标是培养医学博士、医学博士和医学博士。 对成人血液学感兴趣的博士后研究员，从事学术医学和生物医学 研究。约翰霍普金斯大学血液学是最大的独立成人血液学项目之一。我们是 要求每年支持四名博士后实习生，与上一个赠款周期保持不变。 约翰霍普金斯大学血液学奖学金计划，支持每人2名单板血液学研究员 年，是这款T32的主要基材。这个奖学金项目是美国仅有的两个项目之一 它招募单人血液学研究员，并提供良性和恶性方面的专门培训 没有接受过实体肿瘤培训的血液学。因此，拟议的培训方案的目的是准备 拥有医学博士和/或博士学位的合格个人，可从事成人血液学领域的研究工作。这个 培训计划由资金充足和经验丰富的调查人员组成，其中大多数人来自国际 因其在造血学和干细胞生物学、贫血、血红蛋白病、 血栓性微血管病，骨髓衰竭状态和骨髓增殖性疾病。培训得到加强 拥有最先进的研究设施和核心的卓越研究环境，杰出的教职员工 导师，以及一项现有的骨髓移植计划项目赠款。尽管有一股全国性的潮流在远离 从单板血液学奖学金计划，约翰霍普金斯大学继续吸引优秀的MD和 参加单板血液学培训的医学博士/博士候选人，并为他们在生物医学研究中的职业生涯做准备1。 我们的基础科学导师的实验室也有一批杰出的博士后研究员，他们 在血液学多学科会议甚至临床培训计划中得到了很好的整合。 该培训计划的具体目标是： 1)提供与血液学相关的多个领域的研究培训机会，包括良性和 恶性造血，骨髓衰竭，骨髓移植，干细胞生物学， 免疫学、遗传学、血栓性微血管病、骨髓增生性/骨髓增生异常综合征和 血红蛋白病 2)提供与临床、翻译和基础相关的有组织的课程和研讨会的机会 与血液学有关的研究，并提供指导撰写赠款、手稿的机会 写作、公开演讲和生物统计学 3)进行小组辅导，并仔细监测受训人员的进展和培训的总体成功 培训计划 4)解决成人血液学家在学术血液学领域的严重短缺问题

PROJECT SUMMARY/ABSTRACT The primary objective of the Training Program in Hematology, in its 35th year of funding, is to train MD, MD/PhD, and PhD postdoctoral fellows interested in adult hematology for careers in academic medicine and biomedical research. Johns Hopkins Hematology is among the largest free-standing adult hematology programs. We are requesting support for four postdoctoral trainees per year, which is unchanged from the previous grant cycle. The Johns Hopkins Hematology Fellowship Program, which supports 2 single-board hematology fellows per year, is the major substrate for this T32. This fellowship program is one of only 2 programs in the United States that recruits for single-board hematology fellows, and provides dedicated training in benign and malignant hematology without training in solid tumors. Thus, the purpose of the proposed training program is to prepare qualified individuals with an MD and/or PhD degree for a research career in the field of adult hematology. The training program consists of well-funded and highly experienced investigators, most of whom are internationally recognized for their research pertaining to hematopoiesis and stem cell biology, anemias, hemoglobinopathies, thrombotic microangiopathies, bone marrow failure states and myeloproliferative diseases. Training is enhanced by an outstanding research environment with state-of-the-art research facilities and cores, outstanding faculty mentors, and an existing program project grant on bone marrow transplantation. Despite a national trend away from single board hematology fellowship programs, Johns Hopkins continues to attract outstanding MD and MD/PhD candidates for single board hematology training and prepares them for careers in biomedical research1. There is also an exceptional pool of PhD postdoctoral fellows from the labs of our basic science mentors who are well-integrated in the hematology multidisciplinary conferences and even the clinical training program. Specific aims are of this training program are: 1) to provide research training opportunities in a variety of areas pertaining to hematology including benign and malignant hematopoiesis, bone marrow failure disorders, bone marrow transplantation, stem cell biology, immunology, genetics, thrombotic microangiopathies, myeloproliferative/myelodysplastic syndromes and hemoglobinopathies 2) to provide the opportunity for structured coursework and seminars pertaining to clinical, translational and basic research pertaining to hematology, and to provide opportunities for instruction in grant writing, manuscript writing, public speaking and biostatistics 3) to allow for group mentoring, and careful monitoring of the trainees’ progress and the overall success of the training program 4) to address the critical shortage of adult hematologists pursuing careers in academic hematology