Training Program in Hematology

项目总结/摘要 在血液学培训计划的主要目标，在其第35年的资金，是培养医学博士，医学博士/博士， 和博士博士后研究员感兴趣的成人血液学的职业生涯在学术医学和生物医学 research.约翰霍普金斯血液学是最大的独立成人血液学项目之一。我们 申请每年资助四名博士后学员，与上一个赠款周期相比没有变化。 约翰霍普金斯血液学奖学金计划，支持2个单板血液学研究员， 年，是这个T32的主要基板。这个奖学金项目是美国仅有的两个项目之一， 招募单板血液学研究员，并提供良性和恶性肿瘤的专门培训， 没有实体肿瘤的训练。因此，拟议培训方案的目的是准备 具有医学博士和/或博士学位的合格人员，在成人血液学领域从事研究工作。的 培训计划由资金充足和经验丰富的调查人员组成，其中大多数是国际 公认的研究涉及造血和干细胞生物学，贫血，血红蛋白病， 血栓性微血管病、骨髓衰竭状态和骨髓增生性疾病。培训得到加强 由一个优秀的研究环境与国家的最先进的研究设施和核心，优秀的教师 导师，以及现有的骨髓移植计划项目赠款。尽管全国性的趋势是 从单板血液学奖学金计划，约翰霍普金斯继续吸引优秀的医学博士和 MD/PhD候选人进行单板血液学培训，并为他们在生物医学研究中的职业生涯做好准备1。 还有一个特殊的博士博士后研究员从我们的基础科学导师的实验室谁 在血液学多学科会议甚至临床培训计划中得到很好的整合。 该培训方案的具体目标是： 1)提供与血液学相关的各种领域的研究培训机会，包括良性和 恶性造血，骨髓衰竭病症，骨髓移植，干细胞生物学， 免疫学、遗传学、血栓性微血管病、骨髓增生性/骨髓增生异常综合征和 血红蛋白 2)提供有关临床，翻译和基础的结构化课程和研讨会的机会 有关血液学的研究，并提供机会，指导赠款写作，手稿 写作、公开演讲和生物统计学 3)允许小组辅导，并仔细监测学员的进展和整体成功的 培训计划 4)以解决从事学术血液学职业的成人血液学家的严重短缺问题，

PROJECT SUMMARY/ABSTRACT The primary objective of the Training Program in Hematology, in its 35th year of funding, is to train MD, MD/PhD, and PhD postdoctoral fellows interested in adult hematology for careers in academic medicine and biomedical research. Johns Hopkins Hematology is among the largest free-standing adult hematology programs. We are requesting support for four postdoctoral trainees per year, which is unchanged from the previous grant cycle. The Johns Hopkins Hematology Fellowship Program, which supports 2 single-board hematology fellows per year, is the major substrate for this T32. This fellowship program is one of only 2 programs in the United States that recruits for single-board hematology fellows, and provides dedicated training in benign and malignant hematology without training in solid tumors. Thus, the purpose of the proposed training program is to prepare qualified individuals with an MD and/or PhD degree for a research career in the field of adult hematology. The training program consists of well-funded and highly experienced investigators, most of whom are internationally recognized for their research pertaining to hematopoiesis and stem cell biology, anemias, hemoglobinopathies, thrombotic microangiopathies, bone marrow failure states and myeloproliferative diseases. Training is enhanced by an outstanding research environment with state-of-the-art research facilities and cores, outstanding faculty mentors, and an existing program project grant on bone marrow transplantation. Despite a national trend away from single board hematology fellowship programs, Johns Hopkins continues to attract outstanding MD and MD/PhD candidates for single board hematology training and prepares them for careers in biomedical research1. There is also an exceptional pool of PhD postdoctoral fellows from the labs of our basic science mentors who are well-integrated in the hematology multidisciplinary conferences and even the clinical training program. Specific aims are of this training program are: 1) to provide research training opportunities in a variety of areas pertaining to hematology including benign and malignant hematopoiesis, bone marrow failure disorders, bone marrow transplantation, stem cell biology, immunology, genetics, thrombotic microangiopathies, myeloproliferative/myelodysplastic syndromes and hemoglobinopathies 2) to provide the opportunity for structured coursework and seminars pertaining to clinical, translational and basic research pertaining to hematology, and to provide opportunities for instruction in grant writing, manuscript writing, public speaking and biostatistics 3) to allow for group mentoring, and careful monitoring of the trainees’ progress and the overall success of the training program 4) to address the critical shortage of adult hematologists pursuing careers in academic hematology