课题基金 / 基金详情

Effects of redox homeostasis on cancer and cardiovascular diseases

Effects of redox homeostasis on cancer and cardiovascular diseases
氧化还原稳态对癌症和心血管疾病的影响
批准号：
8939832
负责人：
PAUL M. HWANG
金额：
$58.39万
依托单位：
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/8939832
关键词：
AerobicAffectBiologyCardiovascular DiseasesCardiovascular systemCell modelCellular StressDNA DamageDevelopmentEnergy MetabolismGeneticGenomic DNAHealthHomeostasisHumanLifeMalignant NeoplasmsMethodsMitochondriaNuclearOxidation-ReductionOxygenPathogenesisReactive Oxygen SpeciesStressmitochondrial dysfunctionmouse modelneoplastic cellpreventtumorigenesis

项目摘要

项目成果

PAUL M. HWANG的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
Our previous studies have suggested that mitochondrial dysfunction causes oxidative genomic DNA damage and contributes to tumorigenesis. Oxygen also serves as an essential substrate for reactive oxygen species formation but it is also essential by aerobic life. We are currently using environmental and genetic methods to modulate oxygen homeostasis and to examine their effect on energy metabolism and tumorigenesis. We are also examining adaptive mechanisms by which cells of neoplastic or cardiovascular origin survive under oxidative or other toxic stress conditions.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Genetic insights into mitochondrial function, cancer and cardiovascular diseases
Effects of redox homeostasis on cancer and cardiovascular diseases
Redox homeostasis in cancer and cardiovascular diseases
Redox homeostasis in cancer and cardiovascular diseases
海外基金