Regulation of Embryonic Stem Cell Self-Renewal
Regulation of Embryonic Stem Cell Self-Renewal
批准号:
8598889
负责人:
C. Anthony Blau
金额:
$35.93万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2013
资助国家:
美国
项目状态:
已结题
起止时间:
2013-12-01 至 2017-11-30
关键词:
AdoptedAffectAnimalsAntibodiesBiological AssayBlood capillariesButyratesCardiac MyocytesCellsCharacteristicsCo-ImmunoprecipitationsCollaborationsCommitComputer AnalysisConfocal MicroscopyDiapauseDistantEmbryoEnvironmentEpiblastEpigenetic ProcessEventFoundationsFunctional RNAFundingGenesGoalsHistone Deacetylase InhibitorHumanImmunofluorescence ImmunologicIn VitroInner Cell MassIsoelectric FocusingKnockout MiceLearningLightMass Spectrum AnalysisMessenger RNAMetabolicMicroRNAsModelingModificationMolecularMusOrganismPathway interactionsPhosphorylationPhysiologicalPluripotent Stem CellsPost-Translational Protein ProcessingProcessProtein IsoformsProteinsRNA SequencesRegulationSTK11 geneSignal PathwaySignaling ProteinStarvationStem cellsStressTechniquesTestingTissuesanimationbasecancer stem cellcapillaryembryonic stem cellhuman embryonic stem cellimplantationin vitro Modelin vivoin vivo Modelinstrumentinterestmembernatural Blastocyst Implantationnotch proteinnovelpluripotencypreimplantationprogenitorresponseself-renewalsuccinyl-trialanine-4-nitroanilidetranscriptome sequencing
中文摘要
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英文摘要
Project 1 will investigate the molecular basis of stem cell quiescence using the physiological phenomenon known as diapause as a model. We will also test whether similar molecular events occur in human pluripotent stem cells. Specific Aim 1 will use a diapause model to characterize stem cell quiescence in vivo, while Specific Aim 2 will characterize stem cell quiescence using novel in vitro models.
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Regulation of Embryonic Stem Cell Self-Renewal
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批准号:8460654
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项目类别:
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资助金额:$35.5万
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财政年份:2012
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负责人:C. Anthony Blau
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依托单位:
Modeling Mammalian Genomes
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批准号:8269673
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项目类别:
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资助金额:$60.61万
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财政年份:2011
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负责人:C. Anthony Blau
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依托单位:
Modeling Mammalian Genomes
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批准号:8460150
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项目类别:
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资助金额:$58.7万
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财政年份:2011
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负责人:C. Anthony Blau
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依托单位:
Modeling Mammalian Genomes
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批准号:8135058
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项目类别:
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资助金额:$60.88万
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财政年份:2011
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负责人:C. Anthony Blau
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依托单位:
Cell Biosystems Firefly 3000 system
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批准号:7792826
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项目类别:
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资助金额:$31.84万
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财政年份:2010
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负责人:C. Anthony Blau
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依托单位:
Self Renewal and Differentiation of Embryonic Stem Cells
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批准号:7928595
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项目类别:
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资助金额:$94.04万
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财政年份:2009
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负责人:C. Anthony Blau
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依托单位:
Erythropoietin Blockade for the Treatment of Cancer
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批准号:8125048
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项目类别:
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资助金额:$40.14万
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财政年份:2008
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负责人:C. Anthony Blau
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依托单位:
Erythropoietin Blockade for the Treatment of Cancer
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批准号:8300194
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项目类别:
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资助金额:$40.26万
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财政年份:2008
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负责人:C. Anthony Blau
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依托单位:
Erythropoietin Blockade for the Treatment of Cancer
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批准号:7692926
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项目类别:
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资助金额:$40.83万
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财政年份:2008
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负责人:C. Anthony Blau
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依托单位:
Self Renewal and Differentiation of Embryonic Stem Cells
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批准号:8119430
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项目类别:
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资助金额:$192.73万
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财政年份:2007
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负责人:C. Anthony Blau
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依托单位:
Self Renewal and Differentiation of Embryonic Stem Cells
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批准号:7303498
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项目类别:
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资助金额:$192.83万
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财政年份:2007
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负责人:C. Anthony Blau
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依托单位:
Administrative Core
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批准号:7356492
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项目类别:
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资助金额:$12.52万
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财政年份:2007
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负责人:C. Anthony Blau
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依托单位:
Self Renewal and Differentiation of Embryonic Stem Cells
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批准号:7475086
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项目类别:
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资助金额:$195.56万
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财政年份:2007
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负责人:C. Anthony Blau
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依托单位:
Self Renewal and Differentiation of Embryonic Stem Cells
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批准号:7903429
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项目类别:
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资助金额:$194.68万
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财政年份:2007
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负责人:C. Anthony Blau
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依托单位:
Regulation of Human Embryonic Stem Cell Self-Renewal
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批准号:7356487
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项目类别:
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资助金额:$33.88万
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财政年份:2007
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负责人:C. Anthony Blau
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依托单位:
Self Renewal and Differentiation of Embryonic Stem Cells
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批准号:7664942
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项目类别:
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资助金额:$195.65万
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财政年份:2007
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负责人:C. Anthony Blau
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依托单位:
Self Renewal and Differentiation of Human Embryonic Stem Cells
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批准号:8414915
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项目类别:
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资助金额:$198.19万
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财政年份:2007
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负责人:C. Anthony Blau
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依托单位:
Self Renewal and Differentiation of Human Embryonic Stem Cells
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批准号:8598888
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项目类别:
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资助金额:$197.0万
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财政年份:2007
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负责人:C. Anthony Blau
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依托单位:
Receptor Specifcity in the Proliferation and Differentiation of Stem Cells
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批准号:7076455
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项目类别:
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资助金额:$31.88万
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财政年份:2006
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负责人:C. Anthony Blau
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依托单位:
Receptor Specifcity in the Proliferation and Differentiation of Stem Cells
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批准号:7227439
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项目类别:
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资助金额:$31.03万
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财政年份:2006
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负责人:C. Anthony Blau
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依托单位:
海外基金