Musculoskeletal Quantitative Imaging and Image Processing Research Core

肌肉骨骼成像和图像处理研究（MQIR）核心的目标是提供 定制的图像采集、重建和定量分析，用于临床前（组织样本和 动物模型）和人体肌肉骨骼疾病定量成像。MQIR核心具有 作为其对CCMBM总体使命的贡献的一部分，具体目标I：提供定量磁共振成像序列、计算机断层扫描（CT） 和正电子发射断层扫描（PET）方法用于临床前和人类肌肉骨骼组织。具体目标II：开发新的图像分级和定量分析：提供模板，培训， 并对X光片、CT和MR图像、软件包的临床分级实施强有力的措施 用于图像的后处理、可视化和定量分析。具体目标III：提供成像数据的解释，并评估与生化、组织学和免疫学的联系。 生物力学测量开发和维护记录参数的拟议项目数据库 从单次和连续成像检查中提取的图像，以及相关的临床或实验 端点。具体目标四：我们将提供一个门户网站，以前使用成像的研究的例子 临床和研究成像服务的端点和详细描述将在网络上呈现 portal.工作人员将审查新用户关于研究合作和服务的联机请求， 并根据研究结果，初步谘询有关人士。后处理和 将提供成像信息学，以帮助研究人员设计研究和申请他们的试点， 可行性赠款。具体目标五：我们还将积极开展外联活动，吸引潜在的新用户，参加CCMBM研讨会活动，提供成像研讨会和讲习班，介绍新的成像，图像处理， 核心社区。

The goal of the Musculoskeletal Imaging and Image Processing Research (MQIR) Core is to provide customized image acquisition, reconstruction and quantitative analysis for pre-clinical (tissue samples and animal models), and human quantitative imaging in musculoskeletal diseases.The MQIR Core has the following aims as part of its contribution to the overall mission of the CCMBM. Specific Aim I: To provide quantitative magnetic resonance imaging sequences, computed tomography (CT) and positron emission tomography (PET) methods for pre-clinical and human musculoskeletal tissues. Specific Aim II: To develop novel image grading and quantitative analysis: To provide templates, training, and implement robust measures for clinical grading of radiographs, CT and MR images, software packages for post-processing, visualization and quantitative analysis of images. Specific Aim III: To provide interpretation of imaging data and assess links to biochemical, histological, and biomechanical measures. Develop and maintain databases for proposed projects that record parameters that are extracted from single and serial imaging examinations and the relevant clinical or experimental endpoints. Specific Aim IV: We will provide a web portal, examples of previous studies that have used imaging endpoints and detailed descriptions of clinical and research imaging services will be represented on the web portal. On-line requests from new users for research collaboration and service will be reviewed by the staff, and based on the studies, initial consultation with appropriate individuals will be set up. Post-processing and imaging informatics will be provided to assist researchers design studies and apply for their Pilot and Feasibility grants. Specific Aim V: We will also perform proactive outreach to attract potential new users, participate in CCMBM seminar activities to provide imaging seminars and workshops to introduce new imaging, image processing, to the Core community.