Contextual risk factors for substance use in adolescent Reservation-Dwelling American Indians

居住在保留地的美洲印第安人青少年中物质使用的背景风险因素

• 批准号: 9204503
• 负责人: Nichea Solomon Spillane
• 金额: $ 17.3万
• 依托单位: UNIVERSITY OF RHODE ISLAND
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-01 至 2017-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9204503
• 关键词: Contextual; risk; factors; substance; use

Project Summary/Abstract The long-term goal of the K08 Mentored Research Clinical Scientist Development Award is to expand the applicant's research capabilities to include adolescent Reservation-dwelling American Indian (RDAIs) substance use. The proposed training and research plan fit well with NIDA's strategic plan to promote research on health disparities related to substance use and to increase minority representation in substance use research. The candidate is an American Indian, and her prior research experiences have been in the area of health disparities related to alcohol use in adult RDAIs, involving quantitative methodologies. Although research shows that RDAI adolescents are at a higher risk for substance use, we know little about the reasons for this increased risk. In a group of adult RDAIs, we found that RDAIs as a group expected less of a drop in access to some basic reinforcers (access to housing, employment, etc) as a function of heavy drinking compared to middle class Caucasians. Because adults typically begin using alcohol and other drugs during adolescence, studying reinforcers for not using in adolescent RDAIs is a high public health priority. The present application proposes a structured program of mentoring, training, and supervised research to increase the candidate's capacity to conduct high-quality research blending state of the art qualitative and quantitative methodologies. This K08 will accomplish these objectives through the career development and research plans. The career development plan consists of mentored training in measurement development, adolescent development as it relates to substance use, adolescent American Indian substance use research, qualitative and advanced quantitative methods, and training in translating research findings to treatment and prevention development. The Brown University Center for Alcohol and Addiction Studies provides an intellectually stimulating environment with outstanding resources to ensure the successful achievement of the candidate's training plan. The candidate has assembled a team of mentors who are each experts and nationally known for their research in areas specific to the training plan. Dr. Christopher Kahler (primary mentor) is an expert in measurement development, advanced quantitative methods, and translational research. Dr. Don Operario (co- mentor) is an expert in community based participatory research focusing on health disparities in ethnically diverse populations, and in the use and implementation of mixed qualitative and quantitative methods. Dr. Kristina Jackson (co-mentor) is an expert in adolescent development and substance use involvement. Finally, Dr. Paul Spicer (co-mentor) is an expert in American Indian research with adults and adolescents. The research plan proposes a three phase plan to test a theory of risk for substance use in adolescent RDAIs. The first phase employs qualitative methods to identify and construct a typology of factors unique to this population – i.e., the social/environmental, cultural, and developmental context - that might reinforce observed patterns of substance use. Based on these interviews, we will develop a measure of these reinforcers to be used in Phase 2. Phase 2 is a psychometric evaluation of the measure that will be developed from the qualitative interviews and focus groups conducted in Phase 1. Phase 3 is a cross-sectional test of the association between these factors and substance use involvement. The candidate will write an R01 in order to follow these individuals to investigate the role of these factors longitudinally. Results of this program of research are expected to ultimately inform the development of a theoretically based, developmentally and culturally appropriate theory to prevent the use and harms associated with substance use in this population. It is anticipated that this prevention intervention model will target important determinants of substance use, which will be characterized in this proposed K-Award and subsequent R01 submission. In sum, this award will provide the candidate the necessary expertise to develop an independent innovative research program that will generate findings that will contribute to our understanding of risk for substance use in this high risk RDAI group and inform more effective prevention and intervention programs.

项目总结/摘要 K 08指导研究临床科学家发展奖的长期目标是扩大 申请人的研究能力，包括青少年保留地居住的美国印第安人（RDAI） 物质使用。拟议的培训和研究计划与NIDA促进研究的战略计划非常吻合 关于与药物使用有关的健康差距和增加少数群体在药物使用方面的代表性 research.候选人是美国印第安人，她以前的研究经验一直在该地区， 与成人RDAI中酒精使用相关的健康差异，涉及定量方法。虽然 研究表明，RDAI青少年使用药物的风险更高，我们对原因知之甚少 对于这种增加的风险。在一组成年RDAI中，我们发现RDAI作为一个群体， 由于大量饮酒而获得某些基本福利（获得住房、就业等） 与中产阶级的白人相比。因为成年人通常开始使用酒精和其他药物， 在青少年时期，研究不用于青少年RDAI的药物是一个高度优先的公共卫生事项。本 申请提出了一个指导，培训和监督研究的结构化计划，以增加 候选人进行高质量研究的能力，将最先进的定性和定量相结合 方法论。K 08将通过职业发展和研究计划实现这些目标。 职业发展计划包括测量发展、青少年 发展，因为它涉及到物质使用，青少年美国印第安人物质使用研究，定性 先进的定量方法，以及将研究结果转化为治疗和预防的培训 发展布朗大学酒精和成瘾研究中心提供了一个智力上的 激励环境与优秀的资源，以确保候选人的成功实现 培训计划。候选人已经组建了一个导师团队，每个人都是专家， 他们在培训计划特定领域的研究。克里斯托弗·卡勒博士（初级导师）是一位专家， 测量发展，先进的定量方法和转化研究。Don Operario博士（合作伙伴） 导师）是一个专家，在社区为基础的参与性研究，重点是健康差距的种族 不同的人群，以及混合定性和定量方法的使用和实施。博士 克里斯蒂娜杰克逊（共同导师）是青少年发展和物质使用参与的专家。最后， 博士保罗斯派塞（共同导师）是美国印第安人研究与成人和青少年的专家。的 研究计划提出了一个三阶段计划，以测试青少年RDAI中物质使用风险的理论。的 第一阶段采用定性方法，以确定和构建一个类型的因素，独特的这一人口 - 也就是说，社会/环境，文化和发展背景-这可能会加强观察到的模式， 物质使用。根据这些访谈，我们将制定一个用于第三阶段的衡量标准， 2.第二阶段是从定性访谈中发展出来的心理测量评估 和第一阶段的焦点小组。第三阶段是对这些因素之间的关联进行横断面测试。 因素和物质使用参与。候选人将写一个R 01，以便跟随这些人， 纵向研究这些因素的作用。该研究计划的结果预计将 最终为发展一个基于理论的、在发展和文化上适当的理论提供信息， 防止在这一人群中使用与物质使用相关的危害。预计这一 预防干预模式将针对药物使用的重要决定因素， 在本建议的K-奖和随后的R 01提交。总之，这个奖项将为候选人提供 必要的专业知识，以开发一个独立的创新研究计划，将产生的结果， 有助于我们了解高风险RDAI人群中物质使用的风险，并更有效地告知 预防和干预方案。

项目成果

Testing the competing life reinforcers model for substance use in reserve-dwelling First Nation youth.

• DOI: 10.1037/ort0000543
• 发表时间: 2021
• 期刊: The American journal of orthopsychiatry
• 作者: Spillane NS;Schick MR;Nalven T;Goldstein SC;Kirk-Provencher KT;Hill D;Kahler CW
• 通讯作者: Kahler CW

Application of the acquired preparedness model for alcohol and cigarette use among reserve-dwelling first nation adolescents.

• DOI: 10.1037/adb0000798
• 发表时间: 2022-12
• 期刊: PSYCHOLOGY OF ADDICTIVE BEHAVIORS
• 影响因子: 3.4
• 作者: Schick, Melissa R;Williams, Jessica N;Kirk-Provencher, Katelyn T;Cyders, Melissa A;Spillane, Nichea S
• 通讯作者: Spillane, Nichea S

Emotion-based impulsivity, smoking expectancies, and nicotine dependence in college students.

大学生基于情绪的冲动、吸烟预期和尼古丁依赖。

• DOI: 10.3109/16066359.2012.748894
• 发表时间: 2013
• 期刊: Addiction research & theory
• 影响因子: 2.9
• 作者: Spillane,NicheaS;Combs,JessicaL;Kahler,ChristopherW;Smith,GregoryT
• 通讯作者: Smith,GregoryT

Creation and validation of the barriers to alcohol reduction (BAR) scale using classical test theory and item response theory.

使用经典测试理论和项目反应理论创建和验证酒精减少障碍（BAR）量表。

• DOI: 10.1016/j.abrep.2018.01.004
• 发表时间: 2018
• 期刊: Addictive behaviors reports
• 作者: Kunicki,ZacharyJ;Schick,MelissaR;Spillane,NicheaS;Harlow,LisaL
• 通讯作者: Harlow,LisaL

The protective effects of self-compassion on alcohol-related problems among First Nation adolescents.

• DOI: 10.1080/16066359.2021.1902994
• 发表时间: 2022
• 期刊: ADDICTION RESEARCH & THEORY
• 影响因子: 2.9
• 作者: Spillane, Nichea S.;Schick, Melissa R.;Goldstein, Silvi C.;Nalven, Tessa;Kahler, Christopher W.
• 通讯作者: Kahler, Christopher W.