Micro/nano fabrication of x-ray optics for phase-contrast imaging

用于相衬成像的 X 射线光学器件的微/纳米制造

• 批准号: 8939914
• 负责人: HAN WEN
• 金额: $ 97.82万
• 依托单位: NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8939914
• 关键词: Collaborations; Foundations; Generations; Goals; Image; Imaging Device; Laboratories; Medical Imaging; Optics; Phase; Photons; Source; Structure; System; Technology; Testing; United States National Institutes of Health; Universities; beamline; cost; nanofabrication; nanoscale

In the past two years we accomplished advances. The first is to create the first hard x-ray gratings of 200 nm period that can be used to construct a highly sensitive x-ray phase contrast imaging device; the second is to develop the second generation gratings of higher quality and much reduced cost for use in bench-top systems. The first milestone was reached in collaboration with prof. Douglas Wolfe of Penn State University, leading to an ultra-sensitive imaging system on the 2-BM-B beamline of the Advanced Photon Source of Argonne National Laboratory in collaboration with Dr. Francesco De Carlo. The second milestone was reached in collaboration with Nanofab Facility of CNST, NIST. The second generation gratings are being tested in our laboratory at NIH.

在过去的两年里，我们取得了进展。第一个是创建200 nm周期的第一个硬X射线光栅，可用于构建高灵敏度的X射线相衬成像设备;第二个是开发更高质量和更低成本的第二代光栅，用于台式系统。第一个里程碑是与宾夕法尼亚州立大学的道格拉斯沃尔夫教授合作达成的，导致与弗朗西斯科·德卡洛博士合作，在阿贡国家实验室先进光子源的2-BM-B光束线上建立了一个超灵敏成像系统。第二个里程碑是与CNST，NIST的Nanofab Facility合作达成的。第二代光栅正在我们NIH的实验室进行测试。