Investigating Type I Interferon-mediated immune-suppression during Plasmodium infection

研究疟原虫感染期间 I 型干扰素介导的免疫抑制

• 批准号: nhmrc : 1028641
• 负责人: A/Pr Ashraful Haque
• 金额: $ 37.45万
• 依托单位: Queensland Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/investigating-type-i-plasmodium-infection/110656
• 关键词: Investigating; Type; Interferon; mediated; immune

Some infections tend to afflict us only once in our lifetimes, for example chickenpox. This is because our bodies develop immunity to these infections relatively easily. The same is not true for malaria. It is thought that our immune systems are somehow suppressed during this disease. This project aims to understand how the immune system is suppressed during malaria infection, in order that we can block this process, and help our bodies fight this disease more effectively.

有些感染往往一生中只会困扰我们一次，例如水痘。这是因为我们的身体相对容易对这些感染产生免疫力。疟疾的情况并非如此。据认为，我们的免疫系统在这种疾病中受到某种程度的抑制。该项目旨在了解免疫系统在疟疾感染期间如何受到抑制，以便我们可以阻止这一过程，并帮助我们的身体更有效地对抗这种疾病。