Postdoctoral Training Program in Trauma and Hemorrhagic Shock

描述(由申请人提供)：重新设计的这一培训补助金的重点在标题“创伤和失血性休克博士后培训计划”中进行了描述，并在同行评议的期刊上发表了148篇文章，并在地方、地区和国家会议上发表了另外60篇摘要。该培训计划的目标是博士后水平。创伤研究培训计划的目标是培养研究人员成为在学术上具有竞争力的临床科学家，他们能够设计和执行实验室模型来测试与临床相关的假说，与其他科学家合作以增强对他们正在研究的问题的基本理解，并将这些信息转化为临床。为了实现这些目标，我们的计划在每个日历年挑选研究员担任两年的职位。该项目计划招聘有兴趣从事创伤相关研究学术生涯的博士后候选人。在两年的培训结束时，每个研究员都能够：1)批判性地分析可获得的已发表的数据；2)制定有重点的假设；3)设计和执行必要的实验来检验假设；4)分析结果以形成适当的结论并修改实验策略；5)有效地口头和书面地展示他们的研究结果(手稿)；6)准备一个竞争性的研究方案。在完成培训的11名研究员中，有10名从事学术事业，目前担任教职；这些研究员中有5名获得了独立资助。自2001年创建以来，这一T-32训练计划不断发展，最近又加入了新的元素，以推进和集中我们的训练努力。在目前的供资周期中，实验室的重点已演变为研究创伤的全球主题，特别侧重于创伤性脑损伤、复苏和器官损伤/功能障碍。约翰·霍尔科姆博士仍然是培训项目的项目主任，他得到了罗斯玛丽·科扎尔博士和查尔斯·考克斯博士的协助--这两位临床科学家具有重要的翻译研究经验。领导层接受执行委员会和外部审查员的指导。每个学员都有一名初级和初级导师，他们负责确保研究员能够：1)制定有重点的研究方案，2)获得实验室用品、设备和技术指导，3)分析结果，得出结论，修改策略，以及4)组织口头和书面陈述。此外，研究员完成必修和可选的教学课程，参加每周和每月的会议，并参加与合作者的研讨会和座谈会。资源学院成员名单可用于协助项目执行。总而言之，这一全面的方法确保了一支全面、多样化的教职员工将带领这些年轻科学家走上学术独立的道路，并为受伤患者做出重大贡献。

DESCRIPTION (provided by applicant): The redesigned focus of this training grant is described in the title, "Postdoctoral Training Program in Trauma and Hemorrhagic Shock," and has led to 148 publications in peer-reviewed journals, as well as another 60 published abstracts in local, regional and national meetings. This training program is targeted at the postdoctoral level. The goal of the Trauma Research Training Program is to prepare researchers to become academically competitive, clinical scientists who can design and execute laboratory models to test clinically-relevant hypotheses, collaborate with other scientists to enhance the basic understanding of the problem they are studying, and clinically translate this information. To accomplish these goals, our program selects fellows each calendar year for two-year positions. The program plans to recruit postdoctoral candidates who are interested in pursuing an academic career in trauma-related research. At the end of the two years of training, each fellow is able to: 1) critically analyze available published data; 2) formulate a focused hypothesis; 3) design and perform necessary experiments to test the hypothesis; 4) analyze results to formulate appropriate conclusions and modify experimental strategies; 5) effectively present the results of their research both orally and in writing (by manuscript); and 6) prepare a competitive research proposal. Ten of the 11 fellows that completed their training have pursued academic careers and are currently in faculty positions; five of these fellows have been awarded independent funding. Since its creation in 2001, this T-32 training program has evolved, and recently new elements have been added to advance and focus our training efforts. In the current funding cycle, the laboratory focus has evolved into studying the global theme of trauma with particular focus on traumatic brain injury, resuscitation, and organ injury/dysfunction. Dr. John Holcomb remains the Program Director of the training program and he is assisted by Drs. Rosemary Kozar and Charles Cox-two clinical scientists with significant translational research experience. The leadership receives guidance from an Executive Committee and External Reviewers. Each trainee has a Primary and Junior Mentor who are responsible for ensuring the research fellow can :1) formulate a focused research proposal, 2) access laboratory supplies, equipment, and technical instructions, 3) analyze the results, draw conclusions, and revise strategies, and 4) organize both oral and written presentations. Additionally, the fellow complete required and optional didactic coursework, attend weekly and monthly meetings, and participate in seminars and symposia with collaborators. A list of Resource Faculty members are available to assist in project execution. Taken together, this comprehensive approach ensures that a well-rounded, diverse faculty will lead these young scientists along the path to academic independence and significant contributions for injured patients.