Postdoctoral Training Program in Trauma and Hemorrhagic Shock

描述（由申请人提供）：该培训补助金的重新设计的重点在标题中描述，“创伤和出血性休克博士后培训计划”，并在同行评审期刊上发表了148篇论文，以及在地方，区域和国家会议上发表的另外60篇摘要。该培训计划针对博士后水平。创伤研究培训计划的目标是使研究人员成为具有学术竞争力的临床科学家，他们可以设计和执行实验室模型来测试临床相关的假设，与其他科学家合作，以加强对他们正在研究的问题的基本理解，并在临床上翻译这些信息。为了实现这些目标，我们的计划选择研究员每个日历年为期两年的职位。该计划计划招募博士后候选人谁有兴趣在创伤相关的研究追求学术生涯。在两年的培训结束时，每个研究员都能够：1）批判性地分析现有的已发表数据; 2）制定重点假设; 3）设计和执行必要的实验来验证假设; 4）分析结果以制定适当的结论并修改实验策略; 5）有效地口头和书面展示他们的研究结果。（1）准备一份有竞争力的研究计划书。完成培训的11名研究员中有10人从事学术事业，目前担任教职;其中5名研究员获得了独立资助。自2001年创建以来，T-32训练计划不断发展，最近又增加了新的内容，以推进和集中我们的训练工作。在当前的资助周期中，实验室的重点已经演变为研究创伤的全球主题，特别关注创伤性脑损伤，复苏和器官损伤/功能障碍。John Holcomb博士仍然是培训项目的项目总监，他由迷迭香科扎尔博士和查尔斯考克斯博士协助，这两位临床科学家具有重要的转化研究经验。领导层接受执行委员会和外部审查员的指导。每个学员都有一个初级和初级导师谁负责确保研究员可以：1）制定一个重点研究提案，2）访问实验室用品，设备和技术说明，3）分析结果，得出结论，并修改策略，和4）组织口头和书面陈述。此外，研究员完成必修和可选的教学课程，参加每周和每月的会议，并参加研讨会和研讨会与合作者。一份资源学院成员名单可用于协助项目执行。总而言之，这种全面的方法确保了一个全面、多元化的教师队伍将带领这些年轻科学家沿着学术独立的道路，并为受伤的患者做出重大贡献。

DESCRIPTION (provided by applicant): The redesigned focus of this training grant is described in the title, "Postdoctoral Training Program in Trauma and Hemorrhagic Shock," and has led to 148 publications in peer-reviewed journals, as well as another 60 published abstracts in local, regional and national meetings. This training program is targeted at the postdoctoral level. The goal of the Trauma Research Training Program is to prepare researchers to become academically competitive, clinical scientists who can design and execute laboratory models to test clinically-relevant hypotheses, collaborate with other scientists to enhance the basic understanding of the problem they are studying, and clinically translate this information. To accomplish these goals, our program selects fellows each calendar year for two-year positions. The program plans to recruit postdoctoral candidates who are interested in pursuing an academic career in trauma-related research. At the end of the two years of training, each fellow is able to: 1) critically analyze available published data; 2) formulate a focused hypothesis; 3) design and perform necessary experiments to test the hypothesis; 4) analyze results to formulate appropriate conclusions and modify experimental strategies; 5) effectively present the results of their research both orally and in writing (by manuscript); and 6) prepare a competitive research proposal. Ten of the 11 fellows that completed their training have pursued academic careers and are currently in faculty positions; five of these fellows have been awarded independent funding. Since its creation in 2001, this T-32 training program has evolved, and recently new elements have been added to advance and focus our training efforts. In the current funding cycle, the laboratory focus has evolved into studying the global theme of trauma with particular focus on traumatic brain injury, resuscitation, and organ injury/dysfunction. Dr. John Holcomb remains the Program Director of the training program and he is assisted by Drs. Rosemary Kozar and Charles Cox-two clinical scientists with significant translational research experience. The leadership receives guidance from an Executive Committee and External Reviewers. Each trainee has a Primary and Junior Mentor who are responsible for ensuring the research fellow can :1) formulate a focused research proposal, 2) access laboratory supplies, equipment, and technical instructions, 3) analyze the results, draw conclusions, and revise strategies, and 4) organize both oral and written presentations. Additionally, the fellow complete required and optional didactic coursework, attend weekly and monthly meetings, and participate in seminars and symposia with collaborators. A list of Resource Faculty members are available to assist in project execution. Taken together, this comprehensive approach ensures that a well-rounded, diverse faculty will lead these young scientists along the path to academic independence and significant contributions for injured patients.