Postdoctoral Training Program in Trauma and Hemorrhagic Shock

描述（由申请人提供）：重新设计的培训资助重点在标题中描述为“创伤和失血性休克博士后培训计划”，并导致在同行评审期刊上发表148篇文章，以及在地方，区域和国家会议上发表另外60篇摘要。该培训计划针对博士后水平。创伤研究培训计划的目标是准备研究人员成为具有学术竞争力的临床科学家，他们可以设计和执行实验室模型来测试临床相关的假设，与其他科学家合作以增强对他们正在研究的问题的基本理解，并在临床上翻译这些信息。为了实现这些目标，我们的项目每年都会选择研究员担任为期两年的职位。该项目计划招收有志于从事创伤相关研究的博士后候选人。在两年的培训结束时，每个研究员都能够：1)批判性地分析现有的已发表数据；2)制定重点假设；3)设计并进行必要的实验来验证假设；4)分析结果，得出相应结论，修改实验策略；5)有效地以口头和书面形式（通过手稿）展示他们的研究成果；6)准备一份有竞争力的研究计划。完成培训的11名研究员中，有10人从事学术事业，目前担任教职；其中5名研究员获得了独立资助。自2001年创建以来，这个T-32训练计划已经发展，最近增加了新的元素来推进和集中我们的训练工作。在当前的资助周期中，实验室的重点已经演变为研究创伤的全球主题，特别是创伤性脑损伤、复苏和器官损伤/功能障碍。John Holcomb博士仍然是培训项目的项目主管，他的助手是dr。罗斯玛丽·科扎尔和查尔斯·考克斯——两位具有丰富转化研究经验的临床科学家。领导层接受来自执行委员会和外部评审人员的指导。每个受训者都有一个初级和初级导师，他们负责确保研究员能够：1)制定重点研究计划，2)获取实验室用品，设备和技术指导，3)分析结果，得出结论，修改策略，4)组织口头和书面报告。此外，研究员完成必修和选修的教学课程，参加每周和每月的会议，并与合作者一起参加研讨会和专题讨论会。一份资源学院成员的名单可以帮助项目的执行。综合起来，这种全面的方法确保了一个全面的，多样化的教师将带领这些年轻的科学家沿着学术独立的道路，为受伤的病人做出重大贡献。

DESCRIPTION (provided by applicant): The redesigned focus of this training grant is described in the title, "Postdoctoral Training Program in Trauma and Hemorrhagic Shock," and has led to 148 publications in peer-reviewed journals, as well as another 60 published abstracts in local, regional and national meetings. This training program is targeted at the postdoctoral level. The goal of the Trauma Research Training Program is to prepare researchers to become academically competitive, clinical scientists who can design and execute laboratory models to test clinically-relevant hypotheses, collaborate with other scientists to enhance the basic understanding of the problem they are studying, and clinically translate this information. To accomplish these goals, our program selects fellows each calendar year for two-year positions. The program plans to recruit postdoctoral candidates who are interested in pursuing an academic career in trauma-related research. At the end of the two years of training, each fellow is able to: 1) critically analyze available published data; 2) formulate a focused hypothesis; 3) design and perform necessary experiments to test the hypothesis; 4) analyze results to formulate appropriate conclusions and modify experimental strategies; 5) effectively present the results of their research both orally and in writing (by manuscript); and 6) prepare a competitive research proposal. Ten of the 11 fellows that completed their training have pursued academic careers and are currently in faculty positions; five of these fellows have been awarded independent funding. Since its creation in 2001, this T-32 training program has evolved, and recently new elements have been added to advance and focus our training efforts. In the current funding cycle, the laboratory focus has evolved into studying the global theme of trauma with particular focus on traumatic brain injury, resuscitation, and organ injury/dysfunction. Dr. John Holcomb remains the Program Director of the training program and he is assisted by Drs. Rosemary Kozar and Charles Cox-two clinical scientists with significant translational research experience. The leadership receives guidance from an Executive Committee and External Reviewers. Each trainee has a Primary and Junior Mentor who are responsible for ensuring the research fellow can :1) formulate a focused research proposal, 2) access laboratory supplies, equipment, and technical instructions, 3) analyze the results, draw conclusions, and revise strategies, and 4) organize both oral and written presentations. Additionally, the fellow complete required and optional didactic coursework, attend weekly and monthly meetings, and participate in seminars and symposia with collaborators. A list of Resource Faculty members are available to assist in project execution. Taken together, this comprehensive approach ensures that a well-rounded, diverse faculty will lead these young scientists along the path to academic independence and significant contributions for injured patients.