CSHL Eukaryotic mRNA Processing Conference

CSHL真核mRNA加工会议

• 批准号: 8907245
• 负责人: DAVID J. STEWART
• 金额: $ 0.4万
• 依托单位: COLD SPRING HARBOR LABORATORY
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-07-01 至 2016-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8907245
• 关键词: Architecture; Area; Back; Binding; Biochemical; Biochemistry; Biogenesis; Bioinformatics; Biological; Cancer Etiology; Cell physiology; Cells; Coffee; Communities; DNA Sequence; Data; Defect; Development; Disease; Drosophila genus; Emerging Technologies; Ensure; Environment; Eukaryota; Eukaryotic Cell; Event; Faculty; Fostering; Future; Gene Expression; Gene Expression Regulation; Genes; Genetic; Genomics; Goals; Human; In Vitro; Individual; Informatics; International; Introns; Investigation; Knowledge; Laboratories; Location; Malignant Neoplasms; Maps; Messenger RNA; Methodology; Methods; MicroRNAs; Molecular; Molecular Biology; Nuclear; Oncogenic; Oral; Organism; Participant; Physiological; Play; Polyadenylation; Postdoctoral Fellow; Process; Property; Proteins; RNA; RNA Interference; RNA Processing; RNA Splicing; Reaction; Reading; Recruitment Activity; Regulation; Regulatory Pathway; Request for Applications; Research; Research Institute; Research Personnel; Scientist; Seasons; Series; Shapes; Students; System; Therapeutic; Transcript; Transport Process; Untranslated RNA; Woman; Yeasts; abstracting; base; biophysical techniques; cell growth; computing resources; disease-causing mutation; genome-wide; graduate student; human disease; insight; interest; mRNA Precursor; man; meetings; member; mouse model; new technology; next generation; posters; public health relevance; skills; success; symposium; unpublished works

 DESCRIPTION (provided by applicant): COLD SPRING HARBOR LABORATORY CONFERENCE EUKARYOTIC mRNA PROCESSING AUGUST 18 - 22, 2015. The proposed conference on "Eukaryotic mRNA Processing" will convene scientists studying various aspects of mRNA processing, transport, RNA interference, RNA turnover and bioinformatics. Major advances have recently been made in all these areas, and the proposed conference will be a timely event for discussing the latest unpublished results and exchanging ideas, thereby fostering new developments in this rapidly moving field. The proposed conference will be the tenth meeting in the series that is held every other year at Cold Spring Harbor Laboratory. The most recent meeting was held in August 2013 and attracted 336 scientists internationally, who are actively investigating various aspects of messenger RNA maturation in eukaryotic cells using genetic, biochemical, molecular, and cell biological approaches. As in the previous meetings, a major focus will be on nuclear events in mRNA maturation, including mRNA splicing and polyadenylation, as well as the relevance of mRNA maturation to the etiology of cancer and other diseases, the connections between mRNA maturation steps, RNA interference, microRNA biogenesis and function, and the application of informatics and genome-wide approaches to the analysis of RNA processing, including the emerging concept of RNA splicing maps. We propose eight plenary sessions and two poster sessions. Each plenary session will be subdivided into two parts (separated by a coffee break) that focus on related but separate topics. This subdivision, successfully piloted at the 2011 meeting, allows a broader representation of fields and we have recruited a diverse set of faculty as session chairs. As always, all speakers will be selected on the basis of the submitted abstracts, which will encourage active participation by junior scientists. We will particularly encourage presentation of unpublished work by the students and postdoctoral fellows who are leading these projects, as has traditionally been a hallmark and a unique strength of the Cold Spring Harbor meetings.

 描述（由申请人提供）：冷泉港实验室会议真核mRNA处理2015年8月18日至22日。拟议中的“真核mRNA加工”会议将召集研究mRNA加工、运输、RNA干扰、RNA周转和生物信息学各个方面的科学家。最近在所有这些领域都取得了重大进展，拟议的会议将是一个及时的活动，讨论最新的未发表的成果和交流思想，从而促进这一迅速发展的领域的新发展。拟议中的会议将是每两年在冷泉港实验室举行的系列会议中的第十次会议。最近一次会议于2013年8月举行，吸引了336名国际科学家，他们正在积极研究真核细胞中信使RNA成熟的各个方面，使用遗传，生物化学，分子和细胞生物学方法。与前几次会议一样，主要重点将是mRNA成熟中的核事件，包括mRNA剪接和聚腺苷酸化，以及mRNA成熟与癌症和其他疾病病因学的相关性，mRNA成熟步骤之间的联系，RNA干扰，microRNA生物发生和功能，以及信息学和全基因组方法在RNA加工分析中的应用，包括RNA剪接图的新概念。我们建议举行八次全体会议和两次海报会议。每次全体会议将分为两个部分（中间有一个喝咖啡的休息时间），重点讨论相关但独立的主题。这种细分，在2011年的会议上成功试点，允许领域的更广泛的代表性，我们已经招募了一组不同的教师作为会议主席。一如既往，所有发言者都将根据提交的摘要挑选，这将鼓励年轻科学家积极参与。我们将特别鼓励领导这些项目的学生和博士后研究员发表未发表的工作，这一直是冷泉港会议的传统标志和独特优势。