Broad Institute LINCS Center for Transcriptomics
Broad Institute LINCS Center for Transcriptomics
批准号:
8787845
负责人:
TODD R. GOLUB
金额:
$209.28万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2014
资助国家:
美国
项目状态:
已结题
起止时间:
2014-09-10 至 2020-06-30
关键词:
BiologicalBiologyBiomedical ResearchClustered Regularly Interspaced Short Palindromic RepeatsCommunitiesDataDevelopmentDiseaseEducation and OutreachGene ExpressionGenesGeneticGenomeGoalsHealth SciencesInstitutesInstitutionInternetKnock-outLinkMapsMethodsOpen Reading FramesPathway interactionsPharmaceutical PreparationsPhasePhysiologicalPhysiologyReadingResearchResearch InfrastructureResearch PersonnelResourcesScientistSourceTherapeutic EffectUnited States National Institutes of HealthWorkanalytical toolbasecell typecloud basedcostdesignknock-downmRNA Expressionnovel strategiesoverexpressionprogramsprotein functionpublic health relevancerepositoryscale upsmall hairpin RNAsmall moleculetooltranscriptomicsuser-friendly
中文摘要
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英文摘要
DESCRIPTION (provided by applicant): The overall goal of this LINCS Center is to make it to generate large-scale pharmacological and genetic perturbations of a large panel of cell types, develop analytical tools that enable researchers to make biological discoveries from the data, and to make those data and tools broadly available to the research community. We will accomplish this using the L1000 transcriptional profiling method developed by our Center, and by creating a cloud-based computing infrastructure that supports data APIs and web apps designed make it possible for biologists lacking computational expertise to make LINCS-based discoveries.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Discovering existing medicines that abrogate cellular responses to SARS CoV-2 infection
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批准号:10199270
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项目类别:
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资助金额:$165.28万
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财政年份:2020
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负责人:TODD R. GOLUB
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依托单位:
Making cancer precision medicine real: bottlenecks and opportunities
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批准号:10018814
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项目类别:
-
资助金额:$102.43万
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财政年份:2019
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负责人:TODD R. GOLUB
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依托单位:
Making cancer precision medicine real: bottlenecks and opportunities
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批准号:10473781
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项目类别:
-
资助金额:$100.38万
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财政年份:2019
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负责人:TODD R. GOLUB
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依托单位:
Making cancer precision medicine real: bottlenecks and opportunities
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批准号:9816920
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项目类别:
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资助金额:$102.43万
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财政年份:2019
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负责人:TODD R. GOLUB
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依托单位:
Making cancer precision medicine real: bottlenecks and opportunities
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批准号:10246428
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项目类别:
-
资助金额:$84.44万
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财政年份:2019
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负责人:TODD R. GOLUB
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依托单位:
Making cancer precision medicine real: bottlenecks and opportunities
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批准号:10687086
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项目类别:
-
资助金额:$100.38万
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财政年份:2019
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负责人:TODD R. GOLUB
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依托单位:
LINCS Data Coordination and Integration Center
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批准号:9096857
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项目类别:
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资助金额:$66.88万
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财政年份:2015
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负责人:TODD R. GOLUB
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依托单位:
LINCS Data Coordination and Integration Center
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批准号:8825090
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项目类别:
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资助金额:$66.88万
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财政年份:2015
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负责人:TODD R. GOLUB
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依托单位:
LINCS Data Coordination and Integration Center
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批准号:9280623
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项目类别:
-
资助金额:$66.88万
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财政年份:2015
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负责人:TODD R. GOLUB
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依托单位:
PQB-3: Discovery and validation of the driving mediators of cancer cachexia
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批准号:8792102
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项目类别:
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资助金额:$55.44万
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财政年份:2014
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负责人:TODD R. GOLUB
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依托单位:
Broad Institute LINCS Center for Transcriptomics
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批准号:9098784
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项目类别:
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资助金额:$210.7万
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财政年份:2014
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负责人:TODD R. GOLUB
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依托单位:
PQB-3: Discovery and validation of the driving mediators of cancer cachexia
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批准号:9333287
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项目类别:
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资助金额:$58.56万
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财政年份:2014
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负责人:TODD R. GOLUB
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依托单位:
Broad Institute Center for Cancer Systems Biology
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批准号:8444659
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项目类别:
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资助金额:$200.61万
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财政年份:2013
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负责人:TODD R. GOLUB
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依托单位:
The Dana-Farber Cancer Institute Cancer Target Discovery and Development Center
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批准号:8654308
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项目类别:
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资助金额:$69.37万
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财政年份:2013
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负责人:TODD R. GOLUB
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依托单位:
Broad Institute Center for Cancer Systems Biology
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批准号:8628529
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项目类别:
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资助金额:$6.87万
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财政年份:2013
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负责人:TODD R. GOLUB
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依托单位:
The Dana-Farber Cancer Institute Cancer Target Discovery and Development Center
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批准号:8494195
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项目类别:
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资助金额:$72.59万
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财政年份:2013
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负责人:TODD R. GOLUB
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依托单位:
Broad Institute Center for Cancer Systems Biology
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批准号:8340111
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项目类别:
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资助金额:$203.27万
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财政年份:2011
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负责人:TODD R. GOLUB
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依托单位:
Large scale gene expression analysis of cellular states
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批准号:8150481
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项目类别:
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资助金额:$232.26万
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财政年份:2010
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负责人:TODD R. GOLUB
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依托单位:
Large scale gene expression analysis of cellular states
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批准号:8254069
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项目类别:
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资助金额:$8.84万
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财政年份:2010
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负责人:TODD R. GOLUB
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依托单位:
Large scale gene expression analysis of cellular states
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批准号:8539125
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项目类别:
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资助金额:$12.0万
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财政年份:2010
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负责人:TODD R. GOLUB
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依托单位:
国内基金
海外基金
Journal of Integrative Plant Biology
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批准号:31024801
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项目类别:专项基金项目
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资助金额:24.0万元
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批准年份:2010
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负责人:贺萍
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依托单位: