Training Program in Urologic Research

描述（由申请人提供）：佛罗里达大学泌尿外科五十多年来培养了许多杰出的泌尿科医生。目前的建议是致力于建立一个新的和转型的努力，通过一个密集的实验室或临床研究为基础的教育计划，旨在为他们提供必要的知识基础，成为成功的独立资助的研究人员教育MD和博士生。对于临床研究者，通过CTSI进行的流行病学、生物统计学、临床试验设计、医学文献的批判性评价和数据库管理方面的正式教学培训构成了培训议程的基础。对于博士来说，建立基础科学的桥梁和跨学科翻译研究团队的发展是一个主要重点。该计划包括20多个特殊的培训教师，分为四个主题相关的科学小组，专注于与泌尿学领域相关的问题。这些小组是尿石症和代谢紊乱（Khan博士、Benjamin Canales博士、Brown博士、Weiner博士、Limacher博士）、干细胞和再生医学（Steindler博士、Scott博士、Reynolds博士、Terada博士）、免疫学/炎症（Clare-Salzler博士、Vieweg博士、Moldawer博士、Chegini博士）、功能基因组学和细胞信号传导（约翰逊博士、Daaka博士、Wood博士、Conrad博士、Stacpoole博士、Nie博士、Shenkman博士）。除了这些导师，临床顾问将协助指导和日常运作的培训补助金计划（博士苏，穆纳卡纳莱斯，鸟，吉尔伯特，达姆，莫伊，杨，斯特林格）。正如将要证明的那样，这个培训补助金教师的成员之间已经存在相当大的互动和合作，并且作为教育工作者和NIH资助的研究人员都有杰出的记录。我们成功地为佛罗里达大学的医学博士和博士生创造了一个与泌尿系统疾病研究相关的基础、应用和临床科学的优质教育环境。

DESCRIPTION (provided by applicant): The Department of Urology at the University of Florida has trained many outstanding academic urologists for more than fifty years. The current proposal is dedicated to establishing a new and transformational effort to educate both MD and PhD trainees through an intense laboratory or clinical investigation-based educational program designed to provide them with the essential intellectual foundation to become successful independently-funded investigators. For clinical investigators, formal didactic training through CTSI in epidemiology, biostatistics, clinical trials design, critical appraisal of medical literatue, and data base management form the basis of the training agenda. For PhDs, the building of bridges to basic science and the development of interdisciplinary translational research teams is a major focus. This program comprises more than twenty exceptional training faculty falling into four thematically-related scientific groups focused on problems pertinent to the field of urology. These groups are urolithiasis and metabolic disorders (Drs. Khan, Benjamin Canales, Brown, Weiner, Limacher), stem cells and regenerative medicine (Drs. Steindler, Scott, Reynolds, Terada) immunology/inflammation (Drs. Clare-Salzler, Vieweg, Moldawer, Chegini), functional genomics and cell signaling (Drs. Johnson, Daaka, Wood, Conrad, Stacpoole, Nie, Shenkman). In addition to these preceptors, clinical advisors will assist with mentoring and day-to-day functioning of the training grant program (Drs. Su, Muna Canales, Bird, Gilbert, Dahm, Moy, Yeung, Stringer). As will be demonstrated, considerable interaction and collaboration already exists between the members of this training grant faculty and all have distinguished records as educators and NIH-funded investigators. We have successfully created a superb environment for high quality education in the basic, applied and clinical sciences relevant to the study of urologic diseases for both the MD and PhD trainee at the University of Florida.