Training Program in Urologic Research

简介（由申请人提供）：佛罗里达大学泌尿外科在五十多年的时间里培养了许多杰出的学术泌尿科医生。目前的提案致力于建立一个新的和转型的努力，通过一个强烈的实验室或临床研究为基础的教育计划，旨在为他们提供必要的智力基础，成为成功的独立资助的研究者。对于临床研究人员，通过CTSI进行流行病学、生物统计学、临床试验设计、医学文献批判性评价和数据库管理方面的正式教学培训构成了培训议程的基础。对于博士来说，建立与基础科学的桥梁和发展跨学科的转化研究团队是一个主要的重点。该计划由二十多名优秀的培训教师组成，分为四个主题相关的科学小组，专注于与泌尿外科领域相关的问题。这两组分别是尿石症和代谢紊乱(dr。Khan, Benjamin Canales, Brown, Weiner, Limacher)，干细胞和再生医学(dr。Steindler, Scott, Reynolds, Terada)免疫学/炎症(dr。Clare-Salzler, Vieweg, Moldawer, Chegini)，功能基因组学和细胞信号传导(dr。Johnson, Daaka, Wood, Conrad, Stacpoole, Nie, Shenkman)。除了这些导师，临床顾问将协助指导和日常运作的培训拨款计划(博士。苏，莫娜·卡纳莱斯，伯德，吉尔伯特，达姆，梅，杨，斯金格)。正如将要展示的那样，这个培训资助的教员成员之间已经存在着相当大的互动和合作，他们都有作为教育者和nih资助的研究者的杰出记录。我们已经成功地为佛罗里达大学的医学博士和博士实习生在泌尿系统疾病研究的基础、应用和临床科学方面创造了一个高质量的教育环境。

DESCRIPTION (provided by applicant): The Department of Urology at the University of Florida has trained many outstanding academic urologists for more than fifty years. The current proposal is dedicated to establishing a new and transformational effort to educate both MD and PhD trainees through an intense laboratory or clinical investigation-based educational program designed to provide them with the essential intellectual foundation to become successful independently-funded investigators. For clinical investigators, formal didactic training through CTSI in epidemiology, biostatistics, clinical trials design, critical appraisal of medical literatue, and data base management form the basis of the training agenda. For PhDs, the building of bridges to basic science and the development of interdisciplinary translational research teams is a major focus. This program comprises more than twenty exceptional training faculty falling into four thematically-related scientific groups focused on problems pertinent to the field of urology. These groups are urolithiasis and metabolic disorders (Drs. Khan, Benjamin Canales, Brown, Weiner, Limacher), stem cells and regenerative medicine (Drs. Steindler, Scott, Reynolds, Terada) immunology/inflammation (Drs. Clare-Salzler, Vieweg, Moldawer, Chegini), functional genomics and cell signaling (Drs. Johnson, Daaka, Wood, Conrad, Stacpoole, Nie, Shenkman). In addition to these preceptors, clinical advisors will assist with mentoring and day-to-day functioning of the training grant program (Drs. Su, Muna Canales, Bird, Gilbert, Dahm, Moy, Yeung, Stringer). As will be demonstrated, considerable interaction and collaboration already exists between the members of this training grant faculty and all have distinguished records as educators and NIH-funded investigators. We have successfully created a superb environment for high quality education in the basic, applied and clinical sciences relevant to the study of urologic diseases for both the MD and PhD trainee at the University of Florida.