Training Program in Urologic Research

描述(由申请者提供)：佛罗里达大学泌尿系培养了许多杰出的学术泌尿科医生50多年。目前的提案致力于建立一种新的变革性努力，通过以实验室或临床调查为基础的强化教育计划，教育医学和博士受训人员，旨在为他们提供成为成功的独立资助研究人员的必要知识基础。对于临床研究人员，通过CTSI进行的流行病学、生物统计学、临床试验设计、医学文献的批判性评估和数据库管理方面的正式教学培训构成了培训议程的基础。对于博士来说，建立通往基础科学的桥梁和发展跨学科的翻译研究团队是一个主要的关注点。该计划包括20多名特殊培训教师，分成四个主题相关的科学小组，专注于与泌尿外科领域相关的问题。这些小组是尿石症和代谢疾病(可汗、本杰明·卡纳莱斯、布朗、韦纳、利马赫博士)，干细胞和再生医学(斯坦德勒、斯科特、雷诺兹、Terada博士)，免疫学/炎症(克莱尔-索尔兹勒、Vieweg、Moldawer、切吉尼博士)，功能基因组学和细胞信号传递(Johnson、Daaka、Wood、Conrad、Stacpoole、Nie、Shenkman博士)。除了这些导师，临床顾问将协助指导和日常运作的培训资助计划(博士苏，穆纳卡纳莱斯，伯德，吉尔伯特，达姆，莫伊，杨，斯特林格)。正如将要证明的那样，这个培训基金的教职员工之间已经存在着相当大的互动和合作，他们都有作为教育工作者和NIH资助的研究人员的杰出记录。我们成功地为佛罗里达大学的医学博士和博士实习生创造了高质量的基础、应用和临床科学教育环境，这些科学与泌尿系统疾病的研究有关。

DESCRIPTION (provided by applicant): The Department of Urology at the University of Florida has trained many outstanding academic urologists for more than fifty years. The current proposal is dedicated to establishing a new and transformational effort to educate both MD and PhD trainees through an intense laboratory or clinical investigation-based educational program designed to provide them with the essential intellectual foundation to become successful independently-funded investigators. For clinical investigators, formal didactic training through CTSI in epidemiology, biostatistics, clinical trials design, critical appraisal of medical literatue, and data base management form the basis of the training agenda. For PhDs, the building of bridges to basic science and the development of interdisciplinary translational research teams is a major focus. This program comprises more than twenty exceptional training faculty falling into four thematically-related scientific groups focused on problems pertinent to the field of urology. These groups are urolithiasis and metabolic disorders (Drs. Khan, Benjamin Canales, Brown, Weiner, Limacher), stem cells and regenerative medicine (Drs. Steindler, Scott, Reynolds, Terada) immunology/inflammation (Drs. Clare-Salzler, Vieweg, Moldawer, Chegini), functional genomics and cell signaling (Drs. Johnson, Daaka, Wood, Conrad, Stacpoole, Nie, Shenkman). In addition to these preceptors, clinical advisors will assist with mentoring and day-to-day functioning of the training grant program (Drs. Su, Muna Canales, Bird, Gilbert, Dahm, Moy, Yeung, Stringer). As will be demonstrated, considerable interaction and collaboration already exists between the members of this training grant faculty and all have distinguished records as educators and NIH-funded investigators. We have successfully created a superb environment for high quality education in the basic, applied and clinical sciences relevant to the study of urologic diseases for both the MD and PhD trainee at the University of Florida.