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475 MHz NMR Spectrometer

475 MHz NMR Spectrometer
475 MHz 核磁共振波谱仪
批准号：
9274390
负责人：
ARTHUR G PALMER
金额：
$92.5万
依托单位：
COLUMBIA UNIVERSITY HEALTH SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
2017
资助国家：
美国
项目状态：
已结题
起止时间：
2017-08-15 至 2019-08-14
来源：
https://reporter.nih.gov/project-details/9274390
关键词：
Biomedical ResearchCustomDeuteriumLaboratoriesMeasuresNMR SpectroscopyNucleic AcidsProteinsRelaxationStructurebiological researchdensityinsightinstrumentinstrumentation

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中文摘要
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英文摘要
Support is requested for a custom-built 475 MHz NMR Spectrometer. This instrument, together with existing 950 MHz instrumentation, will allow efficient spectral density mapping of deuterium (2H) spin relaxation rate constants measured for biomolecules. The advances in deuterium spectral density mapping will enable new insights to be obtained on the relationships between structure, dynamics, and function in protein and nucleic acid molecules involved in a range of biological and biomedical research in user laboratories.
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Acquisition of an 800 MHz NMR Spectrometer Console and Probes
RM1 Center on Macromolecular Dynamics by NMR Spectroscopy at the New York Structural Biology Center (CoMD/NMR)
RM1 Center on Macromolecular Dynamics by NMR Spectroscopy at the New York Structural Biology Center (CoMD/NMR)
Acquisition of a 900 MHz NMR Spectrometer Console and Probes
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