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中文摘要
翻译
TR&D 2 -场循环弛豫测量
英文摘要
TR&D 2 - Field-cycling relaxometry Summary The “Center on Macromolecular Dynamics by NMR Spectroscopy” (CoMD/NMR) will install the world's first field-cycling shuttle system for an 800 MHz NMR spectrometer, to be sited at the New York Structural Biology Center. This instrument will enable applications of relaxometry to DBPs, to significantly increase knowledge of the relevant spectral density functions and therefore allow much more detailed investigations of macromolecular conformational dynamics. Relaxometry is a technique in which a sample is polarized at high static magnetic field, then physically moved to low field for a relaxation period, and subsequently returned to high field for detection. Activities in this TR&D will include evaluation of alternative shuttle designs, development of novel experimental strategies for use of the shuttle probe, and iterative development and validation of analysis approaches to interpret relaxometric data for the DBPs.
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Acquisition of an 800 MHz NMR Spectrometer Console and Probes
RM1 Center on Macromolecular Dynamics by NMR Spectroscopy at the New York Structural Biology Center (CoMD/NMR)
RM1 Center on Macromolecular Dynamics by NMR Spectroscopy at the New York Structural Biology Center (CoMD/NMR)
Acquisition of a 900 MHz NMR Spectrometer Console and Probes
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海外基金
具有抗癌活性的天然产物金霉酸(Aureolic acids)全合成与选择性构建2-脱氧糖苷键
  • 批准号:
    22007039
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    24.0万元
  • 批准年份:
    2020
  • 负责人:
    王黎明
  • 依托单位:
海洋放线菌来源聚酮类化合物Pteridic acids生物合成机制研究
手性Lewis Acids催化的分子内串联1,5-氢迁移/环合反应及其在构建结构多样性手性含氮杂环化合物中的应用
对空气稳定的新型的有机金属Lewis Acids催化剂制备、表征与应用研究
  • 批准号:
    21172061
  • 项目类别:
    面上项目
  • 资助金额:
    30.0万元
  • 批准年份:
    2011
  • 负责人:
    许新华
  • 依托单位: