Minnesota Training Program in Virology

 描述(由申请者提供)：这是“明尼苏达州病毒学培训计划”在经历了一个富有成效的初始资助期后的第一次竞争性续签。病毒学研究的发现使人们对细胞的分子和细胞过程、病毒复制和致病的基本机制以及宿主细胞如何应对病毒感染(即病毒与宿主的相互作用)有了许多基本的见解。病毒及其引发严重疾病和死亡的能力对人类历史产生了深远影响，并不断威胁全球健康和经济稳定。这项培训计划招募了25名有成就的导师，他们拥有积极的研究计划，正在进行各种重要病毒的研究。分子病毒学研究所(IMV)是明尼苏达大学(UMN)病毒学研究的中心，在资源减少的情况下，它一直将病毒学研究作为一项至关重要的大学投资。这类投资包括将于2015年开放的一座8万平方英尺的新微生物大楼，以及1400万美元用于额外的研究基础设施。我们计划培训活动的主要亮点包括扎实的病毒学基础课程以及由IMV赞助的广泛活动，这些活动提供了重要的智力、技术和职业发展机会(即每周一次的病毒学杂志俱乐部、每月一次的IMV研究进展研讨会、每季度一次的IMV病毒研究创新系列讲座、一年一度的UMN-Mayo病毒学和基因治疗杰出讲座、IMV教育和职业发展系列、一年一度的IMV研讨会、一个协作性的“Wisc-e-Sota”T32研讨会和负责任的研究行为年度会议)。学员参与这些培训计划活动，促进了思想交流，促进了合作项目。对受训人员进展情况的监督是在多个层面上进行的，包括由志愿人员方案咨询委员会进行的年度评价。UMN吸引了优秀的博士前实习生。从这个人才库中，优秀的博士前实习生被招募到教员实验室，根据每个教员的研究计划的个人力量。通过IMV提供的广泛职业发展机会，包括主办国内和国际病毒学会议，将学生--包括未被充分代表的少数族裔学生--带到我们的校园，与我们病毒学研究社区的所有成员发展长期的互动，从而促进了实习生的招聘。尽管我们是一个新的培训项目，但我们在培训方面取得了很好的成绩。为了用我们现有的资源完成我们的培训任务，我们请求在接下来的五年资助期内每年支持6个博士前职位。

 DESCRIPTION (provided by applicant): This is the first competitive renewal of the "Minnesota Training Program in Virology" following a highly productive initial funding period. Discoveries in virology research have led to many fundamental insights into molecular and cellular processes of cells, basic mechanisms of viral replication and pathogenesis, and strategies for how host cells respond to viral infection (i.e., virus-host interactions). Viruses and their capacity to caue serious diseases and death have had a profound impact on the history of humanity and continually threaten global health and economic stability. This training program has recruited 25 accomplished preceptors with active research programs that are conducting research on a variety of important viruses. The Institute for Molecular Virology (IMV) serves as the focal point for virology research at University of Minnesota (UMN) and has championed virology research as a critically important university investment at a time of declining resources. Such investment includes a new 80,000-square-foot microbiology building to open in 2015 and $14 million for additional research infrastructure. Key highlight's of the training activities of our program inclue solid foundational coursework in virology as well as a wide-range of IMV-sponsored activities attended by both trainees and trainers that provide important intellectual, technical, and career development opportunities (i.e., weekly Virology Journal Club, monthly IMV Research in Progress seminars, quarterly IMV Innovations in Virus Research Lecture Series, annual UMN- Mayo Distinguished Lectures in Virology & Gene Therapy, the IMV Educational and Career Development Series, the annual IMV Symposium, a collaborative `Wisc-e-sota' T32 symposium, and annual sessions in Responsible Conduct in Research). Trainee participation in these training program activities have fostered the exchange of ideas and stimulated collaborative projects. Oversight of trainee progress is monitored on multiple levels, including yearly evaluations by the IMV Advisory Committee. Outstanding predoctoral trainees are attracted to the UMN. From this pool, outstanding predoctoral trainees are recruited to trainer labs by the individual strength of each trainer's research program. Trainee recruitment is enhanced by the breadth of career development opportunities provided through the IMV that include the hosting of national and international virology meetings that brings students - including underrepresented minority students - to our campus to develop long-lasting interactions with all members of our virology research community. Despite being a new training program we have a strong record of training achievement. To fulfill our training mission with our available resources we request support for 6 predoctoral positions per year for the next five year funding period.