Biology of Aging and Age Related Diseases Training Grant

描述(由申请人提供)：1991年由NIA资助，修订后的T32请求继续支持威斯康星大学麦迪逊分校的4名博士后和4名博士后研究员进行老龄化研究。该计划的主要任务是为有才华的博士后和博士后研究员提供跨学科的、最先进的培训 衰老和相关疾病的生物学和临床/翻译研究。与之前的学员类似，预计下一个资助期的大多数学员将追求成功的学术生涯，并为全国各地在老龄化研究方面的杰出项目提供领导。修订后的申请建立在华盛顿大学在老年学方面的非凡资源基础上，并包括34名(14名女性和20名男性)在老龄化研究方面拥有公认专业知识的教师导师。每一位导师都有进行老龄化研究和培训老年学研究方面的成功科学家的著名历史。根据最初申请的评审者的杰出意见，目前的提议包括初级教师，他们将得到高级教师的共同指导，成为成功的导师。20多年来，这款T32已经获得了大量的机构承诺。本申请包括额外的财政承诺，包括每年支持一个新的博士前职位(即第5个职位)，以及用于支付项目主任和联合主任5%努力的资金。这一应用程序的其他优势包括：1)获得以前未包括在本T32中的老龄化研究新领域的培训；2)包括13名新的教员导师，其中11名为女性；3)初级、中级和高级教员队伍中导师的均衡分配，4)确认本培训计划不与华盛顿大学的任何其他T32教员重叠，5)加强努力，以增加有色人种受训人员的招聘和留住，以及6)在基础生物和临床研究中纳入强有力的培训课程。总体而言，目前修订的T32已经进行了重大修订，并得到了显著加强。它将继续为有才华的年轻科学家提供杰出的培训，包括以实验室为基础的研究以及衰老和相关疾病的临床/翻译研究，并帮助他们在老年学领域开展成功的学术生涯。

DESCRIPTION (provided by applicant): Funded by NIA in 1991, this revised T32 requests continued support for 4 predoctoral and 4 postdoctoral fellows in aging research at the University of Wisconsin-Madison. The major mission of this program is to provide interdisciplinary, state-of-the-art training to talented pre- and post-doctoral fellows in both the biology and clinical/translational research in aging and related diseases. Similar to prior trainees, it is projected that the majority of trainees in the next funding period will pursue successful academic careers, and provides leadership to eminent programs in aging research across the country. The revised application builds upon the remarkable resources of UW in gerontology, and includes 34 (14 women and 20 men) faculty mentors with acknowledged expertise in aging research. Each mentor has a noted history of conducting research in aging and training successful scientists in gerontology research. Based on outstanding input from reviewers of the original application, the present proposal includes junior faculty who will be co-mentored by senior faculty to become successful mentors. For over 20 years, this T32 has received substantial institutional commitment. The present application includes additional financial commitments, including support for a new (i.e., 5th position) predoctoral position each year and funds to cover 5% effort for both the Program Director and Co-Director. Additional strengths of this application include: 1) access to training in new areas of aging research not previously included in this T32, 2) inclusion of 13 new faculty mentors of which 11 are women, 3) balanced distribution of mentors between junior, mid-level and senior faculty ranks, 4) confirmation that this training program does not overlap with any other T32 at UW, 5) enhanced efforts to increase recruitment and retention of trainees of color, and 6) inclusion of a strong training curriculum in both basic biological and clinical research. Overall, the present revised T32 has undergone major revisions and is significantly strengthened. It will continue to provide outstanding training to talented young scientists in both laboratory-based and clinical/translational research in aging and related diseases, and help them launch a successful academic career in gerontology.