Cancer Biology Training Program

摘要 这项相互竞争的续订申请要求Ruth Kirschstein National提供第二次五年支持 得克萨斯大学癌症生物学培训项目研究服务奖(T32) 圣安东尼奥健康科学中心(UTHSCSA)，一家拉美裔服务机构。巨蟹座的目标 生物学培训计划是教育和培训下一代癌症研究人员(预科和 博士后培训生)，以满足对受过癌症生物学多方面培训的科学家日益增长的需求。 自2011年8月T32奖项开始以来，所有实习生职位(1名博士后和3名博士后) 不断地被填满。因此，到目前为止，有四名博士后学生和七名博士后研究员 被任命为T32实习生，其中3人来自生物医学领域代表性不足的人群 科学。展望未来，我们要求资金支持相同数量的博士后(1名)和博士后(3名)。 实习生。学员将根据他们的学术成就和对癌症研究的奉献精神而被挑选出来。 该培训项目有28名教师导师(19名正教授，6名副教授和3名助理 教授；22名男性和6名女性)来自8个系，在研究生院拥有完全的教职员工特权 以及NCI指定的癌症中心、癌症治疗和研究中心(CTRC)以及 多样化的专业知识，为学员提供深度和广度的研究机会。导师们，他们 分享多个协作项目，并具有很强的互动性，有良好的资助研究记录(平均 本年度每位导师的直接成本为50万美元)，以及指导博士后和博士后的费用 伙计们。培训方案包括博士后和博士后实习生，他们的任期为 两到三年。培训课程(包括两门癌症生物学核心课程、一本癌症生物学期刊 俱乐部，以及药物开发讲座系列)强调基本和翻译方法，以提供 在广泛的当代癌症主题方面为博士后和博士后学员提供出色的培训 生物学，并给他们一个坚实的肿瘤学背景，这是他们在研究中取得成功所必需的， 长期的和长期的。该课程最近通过引入新的教学方法而重新焕发活力。 生物信息学，也强调科学交流的培训，有机会提高口语和 写作技巧。该培训计划充分利用了校园内不断增长的基础和临床研究机会 和活跃的研讨会系列，特别是在CTRC-南得克萨斯州唯一由NCI指定的癌症中心，以及 从PI的系主任到大学校长，都提供了强有力的全面制度支持。这 我们机构唯一的NCI资助的T32培训计划是唯一准备培训即将到来的多样化干部的计划 癌症研究人员因为大量代表不足的少数族裔(URM)受训人员被我们的 这使得这是一个独特的机会，可以丰富未来独立调查员队伍的多样性 从事癌症研究。

Abstract This competing renewal application requests a second five-year support by the Ruth Kirschstein National Research Service Award (T32) for our “Cancer Biology Training Program” based at the University of Texas Health Science Center at San Antonio (UTHSCSA), a Hispanic-Serving Institution. The goal of the Cancer Biology Training Program is to educate and train the next generation of cancer researchers (pre- and postdoctoral trainees) to meet the growing demands for scientists trained in multiple facets of cancer biology. Since the start of the T32 award in August 2011, all trainee positions (1 predoctoral and 3 postdoctoral) have continuously been filled. As a result, to date four predoctoral students and seven postdoctoral fellows have been appointed as T32 trainees including three from populations that are underrepresented in the biomedical sciences. Going forward, we request funds to support the same number of predoctoral (1) and postdoctoral (3) trainees. Trainees will be selected for their academic achievements and their dedication to cancer research. The training program has 28 faculty mentors (19 full professors, 6 associate professors, and 3 assistant professors; 22 men and 6 women) from 8 departments who have full faculty privileges in the Graduate School as well as in the NCI-designated Cancer Center, the Cancer Therapy and Research Center (CTRC), and with diverse expertise that provides depth and breadth of research opportunities for trainees. The mentors, who share several collaborative projects and are very interactive, have a strong record of funded research (average direct costs >$500K per mentor in the current year) as well as in mentoring predoctoral and postdoctoral fellows. The Training Program includes predoctoral and postdoctoral trainees who are appointed for a period of two to three years. The training curriculum (including two cancer biology core courses, a cancer biology journal club, and a drug development lecture series) stresses both basic and translational approaches to provide outstanding training for predoctoral and postdoctoral trainees in broad range of contemporary topics in cancer biology and to give them a solid background in oncology necessary for their success in research both near- term and long-term. The curriculum, which has recently been revitalized with introduction of new didactics in bioinformatics, also emphasizes training in scientific communication with opportunities to improve both oral and written skills. The training program leverages the growing basic and clinical research opportunities on campus and active seminar series, especially at CTRC – the only NCI-designated Cancer Center in South Texas, and strong across-the-board institutional support from the PI's department chair to the university president. This sole NCI-funded T32 Training Program at our institution is uniquely poised to train a diverse cadre of upcoming cancer researchers because a large number of underrepresented minority (URM) trainees are attracted to our program making this a unique opportunity to enrich the diversity in the pool of future independent investigators working in cancer research.