CSHL 2019 Eukaryotic mRNA Processing Conference

冷泉港实验室会议 真核细胞的mRNA加工 2019年8月20日至24日 摘要 拟召开的“真核基因加工”会议将召集科学家 研究mRNA的加工、运输、周转和生物信息学的各个方面。 最近在所有这些领域都取得了重大进展，拟议的 会议将是讨论最新未发表成果和 交流思想，从而在这个快速发展的领域促进新的发展。这个 拟议的会议将是每隔一次举行的系列会议中的第十二次会议 在冷泉港实验室度过了一年。最近一次会议是在8月份举行的 2017年，在国际上吸引了329名科学家，他们正在积极研究各种 信使RNA在真核细胞中成熟的几个方面，使用遗传，生化， 分子和细胞生物学方法。与前几次会议一样，一个主要焦点是 将讨论mRNA成熟过程中的核事件，包括mRNA剪接和 多聚腺苷酸化，转录和mRNA成熟步骤之间的联系， 小RNA的生物发生和功能，信息学和全基因组的应用 分析RNA加工以及信使核糖核酸相关性的方法 对癌症和其他疾病的病因学进行加工。我们建议八次全体会议 会议和两个海报会议。每一次全体会议将细分为两次 部分(用咖啡休息时间隔开)，集中在相关但独立的主题上。在……里面 对RNA修饰和RNA作用领域的重大发展的回应 结构，我们扩展了专门讨论这些主题的会议；这 对场地主要运动的适应性有助于将会议保持在裁剪阶段 并确保我们将吸引来自传统和新兴市场的参与者 核糖核酸研究领域。这一分部在2011年会议上成功试行， 允许更广泛的领域代表，我们已经招募了一组不同的领导人 在外地担任会议主席。所有发言者将一如既往地根据 提交摘要，鼓励初级科学家积极参与。我们会 特别鼓励学生展示未发表的作品，并 领导这些项目的博士后研究员，这是传统上的标志 和独具实力的冷泉港会议。

COLD SPRING HARBOR LABORATORY CONFERENCE EUKARYOTIC mRNA PROCESSING AUGUST 20 - 24, 2019 ABSTRACT The proposed conference on “Eukaryotic mRNA Processing” will convene scientists studying various aspects of mRNA processing, transport, turnover and bioinformatics. Major advances have recently been made in all these areas, and the proposed conference will be a timely event for discussing the latest unpublished results and exchanging ideas, thereby fostering new developments in this rapidly moving field. The proposed conference will be the twelfth meeting in the series that is held every other year at Cold Spring Harbor Laboratory. The most recent meeting was held in August 2017 and attracted 329 scientists internationally, who are actively investigating various aspects of messenger RNA maturation in eukaryotic cells using genetic, biochemical, molecular, and cell biological approaches. As in the previous meetings, a major focus will be on nuclear events in mRNA maturation, including mRNA splicing and polyadenylation, the connections between transcription and mRNA maturation steps, small RNA biogenesis and function, the application of informatics and genome-wide approaches to the analysis of RNA processing, as well as the relevance of mRNA processing to the etiology of cancer and other diseases. We propose eight plenary sessions and two poster sessions. Each plenary session will be subdivided into two parts (separated by a coffee break) that focus on related but separate topics. In response to major developments in the fields of RNA modification and the roles of RNA structure in processing, we have expanded the sessions devoted to these topics; this adaptability to the major movements in the field helps keep this meeting at the cutting edge and ensures that we will draw participants from traditional as well as emerging areas of RNA research. This subdivision, successfully piloted at the 2011 meeting, allows a broader representation of fields and we have recruited a diverse set of leaders in the field as session chairs. As always, all speakers will be selected on the basis of the submitted abstracts, which encourages active participation by junior scientists. We will particularly encourage presentation of unpublished work by the students and postdoctoral fellows who are leading these projects, as has traditionally been a hallmark and a unique strength of the Cold Spring Harbor meetings.