Teen Longitudinal Assessment of Bariatric Surgery (Teen LABS) Research Project
Teen Longitudinal Assessment of Bariatric Surgery (Teen LABS) Research Project
批准号:
9763597
负责人:
THOMAS HARRIS INGE
金额:
$115.05万
依托单位国家:
美国
项目类别:
财政年份:
2011
资助国家:
美国
项目状态:
已结题
起止时间:
2011-09-23 至 2021-08-31
关键词:
AbdomenAdolescenceAdolescentAdultAdverse eventAffectAlcohol abuseAlcoholsAncillary StudyBariatricsBehaviorBehavioralBenefits and RisksBlood PressureBody Weight decreasedBone DensityCardiovascular systemCessation of lifeChildChildbirthClinicalCollectionComorbidityDataDisease remissionDocumentationEating BehaviorEnrollmentFolic AcidFunctional disorderFundingFutureGastrectomyGastric BypassGrantHealthHigh Density Lipoprotein CholesterolHospitalizationImpaired cognitionImpairmentIndividualLate EffectsLongterm Follow-upMeasuresMicronutrientsMorbid ObesityNeckObesityObservational StudyOperative Surgical ProceduresOutcomeParticipantPatternPregnancyProceduresQuality of lifeRegulationRelapseRequest for ApplicationsResearch PersonnelResearch Project GrantsResolutionRiskRisk-TakingSafetySurgical complicationTeenagersTimeTransferrinTriglyceridesVisitVitamin DWeightadverse outcomebariatric surgerybasebehavioral constructbone healthcardiovascular risk factorcognitive controlcognitive functioncomparative effectivenessdepressive symptomsexperiencefollow-uploss of control over eatingobesity in childrenoperationprospectiverecruitreward processingtreatment effect
中文摘要
摘要
本申请要求续签目前支持以下五个临床中心的拨款
组成Teen-Labs(TL)联盟。这项多中心、前瞻性、观察性研究
减肥手术的风险和益处成功招募了242名青少年
在参与的临床中心接受减肥手术,并将这些受试者保留了
长期随访。到本供资期间结束时(2016年8月),大多数国家将
完成5年随访。资金的更新将提供一个机会来研究长期-
最常用的Roux-en-Y胃分流术和袖状胃切除术的远期疗效
今天的行动。从第6年到第10年收集额外的纵向措施将非常重要
记录体重减轻和合并症解决的持久性、生活质量、微量营养素状况、
并将确定长期的不良事件。继续收集生物制品将继续
利用辅助研究机制推动调查人员的新发现。添加新的
研究骨骼健康、认知功能和行为模式的措施将进一步增强
研究延伸的价值所在。
英文摘要
Abstract
This application requests renewal of the current grant supporting the five clinical centers that
comprise the Teen-LABS (TL) consortium. This multicenter, prospective, observational study of
the risks and benefits bariatric surgery successfully recruited 242 consecutive adolescents
undergoing bariatric surgery at participating clinical centers and has retained these subjects for
long-term follow up. By the end of the current funding period (August 2016), most will have
completed 5 years of follow-up. A renewal of funding will provide an opportunity to examine long-
term outcomes of Roux en Y gastric bypass and sleeve gastrectomy, the most commonly used
operations today. Collection of additional longitudinal measures from years 6 to10 will importantly
document durability of weight loss and comorbidity resolution, quality of life, micronutrient status,
and will identify long-term adverse events. Continued collection of biospecimens will continue to
drive new discovery by investigators utilizing the ancillary studies mechanism. Addition of new
measures to study bone health, cognitive function, and behavioral patterns will further enhance
the value of an extension of the study.
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会议论文
Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS) renewal
-
批准号:8546334
-
项目类别:
-
资助金额:$86.09万
-
财政年份:2011
-
负责人:THOMAS HARRIS INGE
-
依托单位:
Teen Longitudinal Assessment of Bariatric Surgery (Teen LABS) Research Project
-
批准号:10570332
-
项目类别:
-
资助金额:$117.08万
-
财政年份:2011
-
负责人:THOMAS HARRIS INGE
-
依托单位:
Teen Longitudinal Assessment of Bariatric Surgery (Teen LABS) Research Project
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批准号:10004606
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项目类别:
-
资助金额:$0.0万
-
财政年份:2011
-
负责人:THOMAS HARRIS INGE
-
依托单位:
Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS) renewal
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批准号:8927611
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项目类别:
-
资助金额:$111.83万
-
财政年份:2011
-
负责人:THOMAS HARRIS INGE
-
依托单位:
Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS) renewal
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批准号:8332935
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项目类别:
-
资助金额:$112.82万
-
财政年份:2011
-
负责人:THOMAS HARRIS INGE
-
依托单位:
Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS) renewal
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批准号:8733161
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项目类别:
-
资助金额:$77.91万
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财政年份:2011
-
负责人:THOMAS HARRIS INGE
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依托单位:
Adolescent Bariatrics: Assessing Health Benefits & Risks
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批准号:8076488
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项目类别:
-
资助金额:$30.59万
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财政年份:2010
-
负责人:THOMAS HARRIS INGE
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依托单位:
Adolescent Bariatrics: Assessing Health Benefits & Risks
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批准号:7905403
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项目类别:
-
资助金额:$15.54万
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财政年份:2009
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负责人:THOMAS HARRIS INGE
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依托单位:
COLLECTION AND BANKING OF BIOLOGICAL SPECIMENS
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批准号:7607773
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项目类别:
-
资助金额:$0.39万
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财政年份:2007
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负责人:THOMAS HARRIS INGE
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依托单位:
ADOLESCENT GASTRIC BYPASS AND DIABETIC PRECURSORS
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批准号:7607777
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项目类别:
-
资助金额:$1.5万
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财政年份:2007
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负责人:THOMAS HARRIS INGE
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依托单位:
Adolescent Bariatrics: Assessing Health Benefits & Risks
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批准号:7251919
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项目类别:
-
资助金额:$135.8万
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财政年份:2006
-
负责人:THOMAS HARRIS INGE
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依托单位:
Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS) renewal
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批准号:8253875
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项目类别:
-
资助金额:$118.48万
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财政年份:2006
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负责人:THOMAS HARRIS INGE
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依托单位:
Adolescent Bariatrics: Assessing Health Benefits & Risks
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批准号:8075156
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项目类别:
-
资助金额:$29.78万
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财政年份:2006
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负责人:THOMAS HARRIS INGE
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依托单位:
Adolescent Bariatrics: Assessing Health Benefits & Risks
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批准号:7872884
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项目类别:
-
资助金额:$241.88万
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财政年份:2006
-
负责人:THOMAS HARRIS INGE
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依托单位:
Adolescent Bariatrics: Assessing Health Benefits & Risks
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批准号:7418619
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项目类别:
-
资助金额:$132.15万
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财政年份:2006
-
负责人:THOMAS HARRIS INGE
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依托单位:
Adolescent Bariatrics: Assessing Health Benefits & Risks
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批准号:7615001
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项目类别:
-
资助金额:$165.49万
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财政年份:2006
-
负责人:THOMAS HARRIS INGE
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依托单位:
Adolescent Bariatrics: Assessing Health Benefits & Risks
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批准号:7102047
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项目类别:
-
资助金额:$114.44万
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财政年份:2006
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负责人:THOMAS HARRIS INGE
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依托单位:
ENDOCRINE EVALUATION OF HYPOTHALAMIC OBESITY
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批准号:7374538
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项目类别:
-
资助金额:$0.18万
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财政年份:2005
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负责人:THOMAS HARRIS INGE
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依托单位:
Adolescent Gastric By-Pass and Diabetic Precursors
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批准号:7078566
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项目类别:
-
资助金额:$14.55万
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财政年份:2005
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负责人:THOMAS HARRIS INGE
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依托单位:
ADOLESCENT GASTRIC BYPASS AND DIABETIC PRECURSORS
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批准号:7374556
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项目类别:
-
资助金额:$0.35万
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财政年份:2005
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负责人:THOMAS HARRIS INGE
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依托单位:
海外基金