Johns Hopkins Alzheimer's Disease Research Center
约翰霍普金斯大学阿尔茨海默病研究中心
基本信息
- 批准号:9921614
- 负责人:
- 金额:$ 315.41万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-04-15 至 2025-02-28
- 项目状态:未结题
- 来源:
- 关键词:AgingAlzheimer&aposs DiseaseAlzheimer&aposs disease related dementiaBaltimoreBasic ScienceBehavioralBiological MarkersBiological ModelsBiostatistics CoreCancer Education Grant ProgramCancer Grant Supplements (P30)ClinicalClinical ResearchClinical TrialsCollaborationsCommunitiesDataData AnalysesDevelopmentDiseaseEnrollmentEnvironmentEventFosteringFundingFunding AgencyFutureGoalsGrantGrowthHumanIndividualInstitutionIntramural Research ProgramJointsK-Series Research Career ProgramsLaboratoriesLeadershipLinkLongitudinal StudiesMentorshipMethodologyMethodsMindMolecularNational Institute on AgingNeurosciencesParticipantPatient CarePatientsPhasePilot ProjectsPlayProcessResearchResearch PersonnelResearch TrainingResourcesRoleSourceStrategic PlanningTalentsTherapeuticTissue BanksTissuesTrainingTraining SupportTranslatingUniversitiesWorkbrain tissuedata managementdesigneducation researcheducational atmospherehuman modelimprovedinnovationinsightinterestmeetingsneuropathologynext generationoutreachpre-clinicalprogramsrecruitresearch studysenior faculty
项目摘要
OVERALL – PROJECT SUMMARY/ ABSTRACT
The Johns Hopkins Alzheimer's Disease Research Center (JHADRC) is an integrated program of investigators
whose overarching goal is to improve understanding of the earliest phases of AD and to expand therapeutic
approaches. The overall scientific focus of the JHADRC is on the earliest stages of AD and related disorders in
humans and in model systems, through characterizing the earliest clinical and pathophysiological processes,
and by identifying cellular and molecular events that contribute to the abnormalities in model systems that
capture aspects of the human disorders. We also focus efforts on improving care of patients in the
symptomatic phases of disease. We have made substantial progress with these research goals during the
current funding cycle, supported by a P50 center grant, and propose to continue and expand this work in the
next funding cycle, through a P30 grant mechanism. The proposed Center consists of 6 Cores and one
component : (1) the Administrative Core (Core A), (2) the Clinical Core (Core B), (3) the Data Management and
Biostatistics Core (Core C), (4) the Neuropathology Core (Core D), (5) the Outreach, Recruitment and
Engagement Core (Core E), (6) the Biomarker Core (Core F) and (7) the Research Education Component
(REC). In this application we are also including funds for 3 Developmental Projects; we anticipate funding one
developmental project for 2 years and two developmental projects for 3 years each.
总体-项目摘要/摘要
项目成果
期刊论文数量(0)
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{{ truncateString('MARILYN S. ALBERT', 18)}}的其他基金
Johns Hopkins Alzheimer's Disease Research Center
约翰·霍普金斯大学阿尔茨海默病研究中心
- 批准号:
10591542 - 财政年份:2020
- 资助金额:
$ 315.41万 - 项目类别:
Johns Hopkins Alzheimer's Disease Research Center
约翰·霍普金斯大学阿尔茨海默病研究中心
- 批准号:
10374071 - 财政年份:2020
- 资助金额:
$ 315.41万 - 项目类别:
Development of MRI microvascular biomarkers in cognitive impairment and dementia
认知障碍和痴呆 MRI 微血管生物标志物的开发
- 批准号:
10001049 - 财政年份:2016
- 资助金额:
$ 315.41万 - 项目类别:
Development of MRI microvascular biomarkers in cognitive impairment and dementia
认知障碍和痴呆 MRI 微血管生物标志物的开发
- 批准号:
9770571 - 财政年份:2016
- 资助金额:
$ 315.41万 - 项目类别:
Validation of small vessel vascular contributions to cognitive impairment and dementia (VCID) biomarkers
验证小血管对认知障碍和痴呆 (VCID) 生物标志物的贡献
- 批准号:
10611828 - 财政年份:2016
- 资助金额:
$ 315.41万 - 项目类别:
Validation of small vessel vascular contributions to cognitive impairment and dementia (VCID) biomarkers
验证小血管对认知障碍和痴呆 (VCID) 生物标志物的贡献
- 批准号:
10368371 - 财政年份:2016
- 资助金额:
$ 315.41万 - 项目类别:
Validation of small vessel vascular contributions to cognitive impairment and dementia (VCID) biomarkers
验证小血管对认知障碍和痴呆 (VCID) 生物标志物的贡献
- 批准号:
10888591 - 财政年份:2016
- 资助金额:
$ 315.41万 - 项目类别: