Tissue Pathology Shared Resource

组织病理学共享资源

• 批准号: 9924324
• 负责人: Kar-Ming Fung
• 金额: $ 13.99万
• 依托单位: UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9924324
• 关键词: Biomedical Research; Cancer Center; Cancer Center Support Grant; Clinical; Consultations; Cultured Cells; Diagnosis; Doctor of Philosophy; Equipment; Experimental Designs; Fees; Floor; Funding; Goals; Histology; House Staffs; Image Analysis; Immunohistochemistry; In Situ Hybridization; Infrastructure; Institution; Liquid substance; Malignant Female Reproductive System Neoplasm; NCI Center for Cancer Research; Neoplasm Circulating Cells; Pathologist; Pathology; Peer Review; Productivity; Research; Research Personnel; Resource Sharing; Resources; Scanning; Science; Services; Slide; Specimen; Stains; Technical Expertise; Technology; Time; Tissue imaging; Tissues; base; data warehouse; experience; member; pre-clinical; programs; tissue processing; translational cancer research; tumor

TISSUE PATHOLOGY SHARED RESOURCE – ABSTRACT The Tissue Pathology Shared Resource (TP SR) is a Stephenson Cancer Center (SCC)-managed facility that provides SCC members and other investigators with high-quality histology, immunohistochemistry (IHC) and in situ hybridization (ISH) services, supported by whole slide scanning and image analysis. The TP SR also provides technical consultation on experimental design and interpretation of results. Established in 2012, the TP SR is directed by Kar-Ming Fung, MD, PhD, a board-certified pathologist with over 28 years of experience in diagnosis and tissue-based research. The services and expertise provided by the TP SR are critical to meet the scientific needs and objectives of the SCC. Members in all three of the SCC's research programs use this Shared Resource, with particularly heavy use by members of the Preclinical Translational Cancer Research (PTCR) and Gynecologic Cancers (GC) programs. Since inception, the TP SR has supported numerous NCI and other peer-reviewed funded research for members of these programs (see TP SR Research Strategy section for a full discussion). TP SR equipment and staff are housed in SCC-designated space in the OUHSC's Biomedical Research Center (BRC), providing the 27 BRC-based SCC members with immediate access to this important infrastructure. An additional five SCC members are located in the adjacent Biomedical Sciences Building (BMSB), which has a dedicated internal walkway to BRC. The main tissue processing and imaging activities occupy a total of 655 sf. of SCC-designated space on BRC Floor 4. In 2016, 21 (43%) of the total number of TP SR users (49) were SCC members with peer-reviewed support. The facility also served nine SCC members without peer-reviewed support. SCC members constituted 61% of the total users of the facility, highlighting the high utilization and impact that the facility has on advancing research at the SCC. As is illustrated in the Research Strategy section, SCC member fees for TP SR services are less than or similar to those of surrounding institutions.

组织病理学共享资源-摘要 组织病理学共享资源(TP SR)是斯蒂芬森癌症中心(SCC)管理的设施， 为鳞癌成员和其他研究人员提供高质量的组织学、免疫组织化学(IHC)和 原位杂交(ISH)服务，支持全载玻片扫描和图像分析。TP SR还 提供实验设计和结果解释方面的技术咨询。成立于2012年， TP SR由冯家明医学博士执导，他是一位拥有超过28年经验的董事会认证病理学家 在诊断和基于组织的研究中。TP SR提供的服务和专业知识对于满足 SCC的科学需求和目标。SCC所有三个研究项目的成员都使用这个 共享资源，尤其是临床前转化性癌症研究成员的大量使用 (PTCR)和妇科癌症(GC)计划。从一开始，TP SR就支持了许多NCI 以及针对这些计划成员的其他同行评审资助的研究(请参阅TP SR研究战略 部分进行了全面讨论)。 TP SR设备和工作人员被安置在OUHSC生物医学研究的SCC指定空间中 中心(BRC)，使27个基于BRC的SCC成员能够立即访问这一重要的 基础设施。另外五名SCC成员位于邻近的生物医学科学大楼 (BMSB)，它有一条专用的内部人行道通往BRC。主要的组织处理和成像活动 共占据655平方英尺。位于BRC Floor 4的SCC指定空间。 2016年，TP SR用户总数(49人)中有21人(43%)是拥有同行评审支持的SCC成员。 该设施还为9名SCC成员提供服务，没有经过同行审查的支持。SCC成员占61% 设施的总用户，突出了设施的高利用率和对发展的影响 在SCC的研究。如研究策略部分所示，TP SR服务的SCC会员费用 少于或类似于周围机构的。