Sleep duration and risk for obesity in Mexican American children

项目摘要 拟议的 K01 奖项将为 Martinez 博士提供必要的支持，以实现她的直接目标 培训目标： 1) 获得儿科睡眠科学和测量方面的专业知识，以补充她的强项 营养和身体活动方面的培训，2) 增加对儿童生长和发育的了解 与能量平衡相关，3) 提高她在规划 RCT 的研究设计方面的技能。此次培训将 为她提供建立独立研究计划所需的技能。为了实现这些目标， 马丁内斯博士组建了一支具有相关专业知识的导师团队来填补她的研究空白 经验。她的指导团队包括： 拥有儿科睡眠专业知识的 Ronald Dahl 博士；希拉博士 Gahagan，拥有儿童成长和发展方面的专业知识； Jeanne Tchann 博士，具有拉丁裔家庭方面的专业知识 特别是在拉丁裔家庭中的动态、研究实施、招募和保留；南希·巴特博士与 小儿肥胖和代谢方面的专业知识；帕特里夏·克劳福德 (Patricia Crawford) 博士，拥有社区营养方面的专业知识 和临床试验以及优秀指导的记录。凭借这个 K01 奖项，马丁内斯博士将实现她的目标 长期目标是成为一名独立研究者，进行能量平衡相关研究，研究如何 减少服务不足的拉丁裔儿童的慢性疾病。 墨西哥裔人在美国拉丁裔人口中所占比例最大 他们的肥胖率很高。更好地理解潜在的行为机制 睡眠时间短可能会影响墨西哥裔美国儿童的肥胖对于预防和/或 减少该人群的肥胖和慢性病。马丁内斯博士的研究将集中在：行为 将睡眠时间与肥胖联系起来的机制（即饮食和身体活动）（目标 1）。这些关系将 在墨西哥裔美国人 8-10 岁儿童 (n=323) 的现有数据集中进行检查。对于目标 2 和目标 3，数据 将收集 8-10 岁墨西哥裔美国人的新样本来检查：1）背景因素（即， 就寝时间、睡眠卫生、家庭主义）可能会影响睡眠（目标 2）； 2) 前一天晚上的影响 睡眠持续时间取决于第二天的饮食和身体活动（目标 3）。这项研究将用于规划 随机控制干预，以促进墨西哥人的最佳睡眠、健康饮食和身体活动 美国儿童，将在 K01 奖项结束之前在 R34 拨款申请中提出。

PROJECT ABSTRACT The proposed K01 award will provide Dr. Martinez with the support necessary to achieve her immediate training goals: 1) to gain expertise in pediatric sleep science and measurement to complement her strong training in nutrition and physical activity, 2) to increase understanding of child growth and development as it relates to energy balance, and 3) to advance her skills in research design to plan an RCT. This training will provide her with the skills necessary to establish her independent research program. To achieve these goals, Dr. Martinez has assembled a team of mentors with relevant expertise to fill the gaps of her research experience. Her mentoring team includes: Dr. Ronald Dahl, with expertise in pediatric sleep; Dr. Sheila Gahagan, with expertise in child growth and development; Dr. Jeanne Tschann, with expertise in Latino family dynamics, study implementation, recruitment and retention specifically in Latino families; Dr. Nancy Butte, with expertise in pediatric obesity and metabolism; and Dr. Patricia Crawford, with expertise in community nutrition and clinical trials and a track record of excellent mentorship. With this K01 award, Dr. Martinez will achieve her long-term goal to become an independent investigator conducting energy-balance related research on how to reduce chronic disease in underserved Latino children. Individuals of Mexican descent comprise the largest proportion of the Latino population in the United States and they suffer high rates of obesity. An improved understanding of the underlying behavioral mechanisms by which short sleep duration may impact obesity among Mexican American children is critical to prevent and/or reduce obesity and chronic disease in this population. Dr. Martinez's research will focus on: behavioral mechanisms (i.e., diet and physical activity) that link sleep duration to obesity (Aim 1). These relationships will be examined in an existing data set of Mexican American 8-10-year-olds (n=323). For Aim 2 and Aim 3, data will be collected in a new sample of Mexican American 8-10-year-olds to examine: 1) contextual factors (i.e., bedtime routines, sleep hygiene, familism) that may impact sleep (Aim 2); and 2) the impact of prior night's sleep duration on diet and physical activity the subsequent day (Aim 3). This research will be used to plan a randomized control intervention to promote optimal sleep, healthy eating and physical activity among Mexican American children, to be proposed in a R34 grant application before the end of the K01 award.