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Administrative Supplement to Liquid Helium Recovery System for University of Delaware NMR Core

Administrative Supplement to Liquid Helium Recovery System for University of Delaware NMR Core
特拉华大学 NMR 核心液氦回收系统的行政补充
批准号:
9986137
负责人:
Colin Thorpe
金额:
$20.8万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1979
资助国家:
美国
项目状态:
已结题
起止时间:
1979-07-01 至 2022-06-30

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中文摘要
翻译
摘要 我们申请资金购买和安装液氦回收系统在我们的大学-范围内的核 磁共振(核磁共振)核心,支持正在进行的NIH资助的新研究,由多个 特拉华大学的研究人员。设在化学和生物化学系磁铁厅, 核磁共振核心支持校园内总共370多名研究人员的工作,这些研究人员来自50多个小组 联邦资助的首席调查人员,其中9人由NIGMS资助,4人由NIH其他研究所资助。大多数人 所有仪器都是全天候运行的。平均每年的液氦消耗量约为4600升。它是 预计将在90%的回收率基础上重新回收4140升液氦。 核磁共振波谱是美国国立卫生研究院资助的研究的关键工具,依赖于尖端仪器的可用性 核磁共振核心的能力和不间断运行。世界范围内的氦短缺已经造成了 对我们的核磁共振基础设施造成不利影响。在过去的12个月里,我们的氦供应商Praxair 系统性地未能按期交付产品,未能提供所需数量,危及 我们的核磁共振磁体的操作。鉴于全球氦供应不断减少,再加上稳步增长的 液氦的价格,我们很快就会面临这样的局面,我们将不得不关闭几家或所有的运营 我们的乐器。为了防止这种情况,并确保我们的核磁共振设备的可持续长期运行, 安装液体氦回收系统现在变得至关重要。
英文摘要
ABSTRACT We request funds for the purchase and installation of a liquid helium recovery system in our University-wide Nuclear Magnetic Resonance (NMR) Core, to support the ongoing, and enable new, NIH-funded research by multiple investigators at the University of Delaware. Housed in the Department of Chemistry and Biochemistry Magnet Hall, the NMR Core supports the work of a total of over 370 researchers on campus, coming from the groups of over 50 Federally funded Principal Investigators, of whom 9 are funded by NIGMS, and 4 by other NIH institutes. The majority of the instruments run on a 24/7 basis. The average annual liquid helium consumption is about 4600 liters. It is anticipated that 4140 liters of liquid helium will be recaptured based on a 90% recovery rate. NMR spectroscopy is a critical tool for NIH-funded research and relies on the availability of cutting-edge instrument capabilities and uninterrupted operation of the NMR Core. The worldwide helium shortage has already had a detrimental impact on our NMR infrastructure. During the past 12 months, Praxair, our helium supplier, has systematically failed to deliver the product on schedule and failed to supply the required amounts, jeopardizing the operation of our NMR magnets. Given the dwindling helium supplies worldwide, compounded by the steadily increasing price of liquid helium, we will soon face the situation that we will have to shut down the operation of several or all of our instruments. To prevent this scenario and to assure sustainable long-term operation of our NMR equipment, installation of a liquid He recovery system has now become essential.
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DOI: 10.1021/ja310553h
发表时间: 2013-02-20
期刊: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
影响因子: 15
作者: [Sapra, Aparna, Thorpe, Colin]
通讯作者: Thorpe, Colin
Electron-transferring flavoprotein from pig kidney: flavin analogue studies.
来自猪肾的电子传递黄素蛋白:黄素类似物研究。
DOI: 10.1021/bi00370a050
发表时间: 1986
期刊: Biochemistry
影响因子: 2.9
作者: [Gorelick,RJ, Thorpe,C]
通讯作者: Thorpe,C
Interflavin oxidation-reduction reactions between pig kidney general acyl-CoA dehydrogenase and electron-transferring flavoprotein.
猪肾酰基辅酶A脱氢酶与电子传递黄素蛋白之间的间黄素氧化还原反应。
DOI: 10.1021/bi00345a015
发表时间: 1985
期刊: Biochemistry
影响因子: 2.9
作者: [Gorelick,RJ, Schopfer,LM, Ballou,DP, Massey,V, Thorpe,C]
通讯作者: Thorpe,C
Interaction of 3,4-dienoyl-CoA thioesters with medium chain acyl-CoA dehydrogenase: stereochemistry of inactivation of a flavoenzyme.
3,4-二烯酰基辅酶A硫酯与中链酰基辅酶A脱氢酶的相互作用:黄素酶失活的立体化学。
DOI: 10.1021/bi0109818
发表时间: 2001
期刊: Biochemistry
影响因子: 2.9
作者: [Wang,W, Fu,Z, Zhou,JZ, Kim,JJ, Thorpe,C]
通讯作者: Thorpe,C
共 35 条
    Flavoproteins in Oxidative Protein Folding
    • 批准号:
      8059050
    • 项目类别:
    • 资助金额:
      $10.0万
    • 财政年份:
      2010
    • 负责人:
      Colin Thorpe
    • 依托单位:
    PROVIDE SMALL INSTRUMENTATION
    • 批准号:
      2191071
    • 项目类别:
    • 资助金额:
      $1.49万
    • 财政年份:
      1994
    • 负责人:
      Colin Thorpe
    • 依托单位:
    SMALL INSTRUMENTATION GRANT
    • 批准号:
      3524240
    • 项目类别:
    • 资助金额:
      $2.99万
    • 财政年份:
      1992
    • 负责人:
      Colin Thorpe
    • 依托单位:
    CONFERENCE--ENZYMES, COENZYMES & METABOLIC PATHWAYS
    • 批准号:
      3435106
    • 项目类别:
    • 资助金额:
      $0.5万
    • 财政年份:
      1990
    • 负责人:
      Colin Thorpe
    • 依托单位:
    海外基金