Exposure Assessment Facility Core

暴露评估设施核心项目摘要（暴露FC） 暴露评估设施核心（暴露FC）提高了研究人员的研究能力， 北方曼哈顿环境健康中心（CEHNM），提供多个领域的专业知识， 大学其他地方没有的相互关联的暴露评估服务。核心培养 新的跨学科项目，并支持现有的研究项目，解决重要的环境 健康挑战。接触FC与综合健康科学设施核心（IHSFC）密切合作， 这是调查人员寻求服务的入口和协调点。它还与社区合作， 参与核心（CEC），响应他们对更好的暴露评估的需求，以解决环境问题 他们的社区伙伴的健康问题，以及支持他们的推广和教育活动。 最后，曝光FC与研究设计和数据分析FC合作，以支持CEHNM成员的 从研究启动时对不同现场策略的初步规划开始，分多个阶段进行调查 并在研究完成时对结果进行最终分析、解释和传播。 Exposure FC汇集了收集和分析数据所需的专业知识和设施， CEHNM研究人员进行暴露评估所需的各种分析物。曝光FC 三个实验室：1）环境地球化学，2）过敏原和生物气溶胶和3）痕量有机物。主 暴露FC的使命是为环境污染物的收集和分析提供高质量的支持。 样品（空气、灰尘、水、土壤和其他基质）。Exposure FC还扩展了广泛的生物- IHSFC通过提供分析生物样品中痕量有机物的专业知识和能力， 样品（除环境样品外）和生物气溶胶分析。 Exposure FC在其长期成功记录的基础上，将提供新的和持续的服务， CEHNM成员，CEHNM支持的年轻研究人员和试点获奖者，学员和中心间 伙伴新服务的一个例子是我们开发和验证增强型风险评估的工作 现场方法这些措施包括验证潜在的吸入剂量作为一个新的暴露指标，以及工作， 模块化空气监测器阵列，用于个人和住宅采样，提供实时数据和综合 颗粒物、生物气溶胶和挥发性有机化合物的档案。持续服务包括：1） 就接触评估实地取样战略进行协商; 2）制定和验证新的 采样设备; 3）空气、灰尘、水和土壤收集设备的维护和借用 4）环境样品的实验室分析，包括空气传播的方法开发 颗粒质量，黑碳，元素组成，同位素比，过敏原，真菌，气体浓度， 痕量有机物;以及IHSFC未提供的生物样品中的分析物; 5）培训和指导 工作人员，受训人员和研究人员;和6）应对暴露紧急情况和CEC的需求。

Project Summary of the Exposure Assessment Facility Core (Exposure FC) The Exposure Assessment Facility Core (Exposure FC) enhances the research capabilities of investigators of the Center for Environmental Health in Northern Manhattan (CEHNM) by providing expertise in a number of inter-related exposure assessment services that are not available elsewhere in the University. The Core fosters new interdisciplinary projects and supports existing research projects that address important environmental health challenges. The Exposure FC works closely with the Integrated Health Sciences Facility Core (IHSFC), which is the port of entry and coordination for investigators seeking services. It also works with the Community Engagement Core (CEC), responding to their needs for better exposure assessment to address environmental health concerns of their community partners, as well as to support their outreach and educational activities. Finally, the Exposure FC works with the Study Design and Data Analytics FC to support CEHNM members’ investigations at multiple stages, starting from the initial planning of different field strategies at study start-up and ending with the final analysis, interpretation, and dissemination of results at study completion. The Exposure FC brings together the expertise and facilities necessary for collecting and analyzing a wide array of analytes required for exposure assessment by CEHNM investigators. The Exposure FC has three labs: 1) Environmental Geochemistry, 2) Allergen and Bioaerosols and 3) Trace Organics. The primary mission of the Exposure FC is to provide high-quality support for collection and analysis of environmental samples (air, dusts, water, soil, and other matrices). The Exposure FC also extends the wide array of bio- analyses offered by the IHSFC by providing expertise and capacity for analyzing trace organics in biological samples (in addition to environmental samples), and for bioaerosol analyses. The Exposure FC, building upon its long record of success, will provide new and continuing services to CEHNM members, CEHNM-supported young investigators and pilot awardees, trainees, and inter-center partners. An example of new services is our work developing and validating enhanced exposure assessment field methods. These include validating potential inhaled dose as a new exposure metric, as well as work on a modular array of air monitors for personal and residential sampling for both real-time data and integrative archives of particulate matter, bioaerosols and volatile organic compounds. Continuing services include: 1) consultation on exposure assessment field sampling strategies; 2) development and validation of new sampling equipment; 3) maintenance and loaning of equipment for collection of air, dust, water and soil samples; 4) laboratory analysis of environmental samples including methods development for airborne particulate mass, black carbon, elemental composition, isotope ratios, allergens, fungi, gas concentrations, trace organics; and analytes in biological samples not provided by the IHSFC; 5) training and mentoring of staff, trainees, and researchers; and 6) responding to exposure emergencies and the needs of the CEC.