Research Training Program in Environmental Pediatrics

环境儿科研究培训计划

• 批准号: 10199759
• 负责人: Robert O Wright
• 金额: $ 41.87万
• 依托单位: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-07-01 至 2022-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10199759
• 关键词: Pediatrics; Research Training; Training Programs

PROJECT SUMMARY Children are exposed to multiple environmental hazards—toxic chemicals, social stressors, and the hazards of the built environment. Research indicates that early-life environmental exposures contribute to common pediatric diseases (asthma, learning disorders, birth defects, obesity) and to diseases in adult life. Yet few pediatricians are trained to diagnose, treat, or prevent diseases of environmental origin, and few academic health centers have research programs in environmental pediatrics. The IOM states that there is a national need to expand the scientific workforce in environmental medicine, and new NIH initiatives (CHEAR and ECHO) have emphasized that children's environmental health is a research priority. Thus, there is a clear need for scientists trained in the principles and methodologies of environmental pediatrics. To address that need, the Mount Sinai School of Medicine seeks renewal of its 3-year, interdisciplinary, post-residency/post-doctoral research training program in environmental pediatrics that began in 2007. Two new fellows are admitted per year. Selection is highly competitive, and fellows are a mix of clinically trained pediatricians and doctorally trained research scientists. In year 1, focus is on education training in epidemiology, biostatistics, toxicology, and environmental medicine, and an MPH degree is granted concentrating in epidemiology. In years 2 and 3, emphasis shifts more toward mentored research that produces publications, meeting presentations/posters, and fosters transition toward independent research with an emphasis on K award applications. We provide fellows with a strong methodological base in environmental health principles and a versatile set of skills and resources that they can apply to study a wide range of scientific questions. Each fellow is guided by a mentoring team of clinical and basic scientists. Courses and experiential training are provided in grant writing and responsible conduct of research. Supervised clinical experience in environmental pediatrics is offered to ensure that research training is grounded in clinical translational principles. Formal evaluation of each fellow is conducted semi-annually. An Executive Faculty Committee and an External Advisory Board are already in place. Expected outcomes include authorship of 1-2 research manuscripts, authorship of 2-3 posters or platforms at national meetings, development in year 2 of a K grant proposal, and evidence of transition toward independent investigator status. This program builds on a unique base of children's environmental health research, including a Child Health Exposure Assessment Resource (CHEAR) Lab Hub, the CHEAR Data Center, an NIH P30 Core Center, nearly a dozen child health research cohorts, a Pediatric Environmental Health Specialty Unit, and a unique Exposome Lab that specializes in exposure biomarkers. In the past 9 years, our program has successfully recruited 19 fellows and graduated 12 (6 are active). Five have secured NIH funding. Graduates are currently faculty UC-Davis, NYU, U of Cincinnati, Mount Sinai, as well as working at CDC and for Industry. Our graduates have published over 70 papers in 9 years.

项目摘要 儿童暴露于多种环境危害--有毒化学品、社会压力源和 建筑环境。研究表明，生命早期的环境暴露有助于常见的 儿童疾病（哮喘、学习障碍、出生缺陷、肥胖症）和成人疾病。但很少 儿科医生接受过诊断、治疗或预防环境源性疾病的培训， 健康中心有环境儿科学的研究项目。国际移民组织指出， 需要扩大环境医学的科学劳动力，以及新的NIH倡议（CHEMICAL和 ECHO）强调儿童的环境健康是研究的优先事项。因此，显然需要 为受过环境儿科学原理和方法训练的科学家举办的。为了满足这一需求， 西奈山医学院寻求其3年，跨学科，博士后/博士后的更新 2007年开始的环境儿科学研究培训项目。每两年接纳两名新研究员 年选择是高度竞争性的，研究员是临床训练的儿科医生和医生的混合。 训练有素的研究科学家。在第一年，重点是流行病学，生物统计学，毒理学， 和环境医学，并授予公共卫生硕士学位集中在流行病学。在第二年和第三年， 重点更多地转向指导研究，产生出版物，会议演示/海报， 并促进向独立研究的过渡，重点是K奖的申请。我们提供 研究员在环境卫生原则方面具有坚实的方法基础和一套多方面的技能， 他们可以利用这些资源来研究广泛的科学问题。每一个人都是由一个 临床和基础科学家的指导团队。课程和经验培训提供赠款写作 和负责任的研究行为。在环境儿科学的监督临床经验提供， 确保研究培训以临床转化原则为基础。对每个研究员的正式评估是 半年一次。一个执行学院委员会和一个外部咨询委员会已经在 地方预期成果包括1 - 2篇研究手稿的作者，2 - 3篇海报的作者，或 在国家会议上的平台，在第二年的K赠款提案的发展，以及向 独立调查员身份。该计划建立在儿童环境健康的独特基础上 研究，包括一个儿童健康暴露评估资源（CHESSION）实验室中心，CHESSION数据 中心，一个NIH P30核心中心，近十几个儿童健康研究队列，一个儿科环境中心， 健康专业单位，和一个独特的暴露体实验室，专门研究暴露生物标志物。过去9 多年来，我们的计划已经成功地招募了19名研究员，毕业12名（6名活跃）。五是确保 NIH资助。毕业生目前任教于加州大学戴维斯分校、纽约大学、辛辛那提大学、西奈山大学以及 在疾病控制中心和工业界我们的毕业生在9年内发表了70多篇论文。