Associations among in utero exposure to metals/metal mixtures,stress/stress mixtures, and internalizing problems in early childhood
Associations among in utero exposure to metals/metal mixtures,stress/stress mixtures, and internalizing problems in early childhood
批准号:
10412666
负责人:
Robert O Wright
金额:
$4.08万
依托单位国家:
美国
项目类别:
财政年份:
2016
资助国家:
美国
项目状态:
已结题
起止时间:
2016-09-21 至 2023-08-31
关键词:
AddressAgeAnxietyBiological AssayChemicalsChild Behavior ChecklistCollaborationsDataGoalsHealthJointsKnowledgeLifeLinkManuscriptsMeasuresMental HealthMetal exposureMetalsNational Institute of Environmental Health SciencesOutcomePoliciesPreparationProtocols documentationPsychopathologyPublishingResearchResearch PersonnelResearch TrainingResidenciesRiskRoleSamplingStressWorkchildhood anxietycohortdepressive symptomsearly childhoodexperiencehealth disparitymedical schoolsmetal complexneurotoxicityparent projectprenatalprenatal exposureprogramssocial stressorurinary
中文摘要
布兰登·高德森补充研究的总体目标是利用母项目
英文摘要
The overall goal of Brandon Goldson’s supplemental research is to leverage the parent project’s
exposure expertise and measures (metals, stress) to address a research gap by examining
associations between these exposures, starting prenatally, and early childhood antecedents of
mental health risk. The project will also leverage planned urinary metals assays for n~3,000
PRISM ECHO prenatal samples which can be pooled with this supplement through Big Win
analysis proposal HHEAR EC0376, and stress measures and the Child Behavior Checklist
(CBCL) collected through the ECHO-wide cohort protocol with guidance on harmonization
across life stage by PRO Core investigators, to examine the influence of complex metal and/or
stress mixtures on transdiagnostic (TD) features linked to anxiety and depressive problems
assessed up to ages 3-6 years. The proposal includes collaborations with ECHO HHEAR and
PRO Core components. This supplement will support Brandon Goldson to work with the
PRISM/ECHO investigator team at the Icahn School of Medicine at Mount Sinai to
conduct and interpret analyses focused on both 6-mo and 3-yr outcome data and to gain
experience in manuscript preparation. This opportunity will expand his knowledge in the role
of metals in neurotoxicity, specifically their potential impact on early psychopathology which
remains largely unexplored. He will also gain a greater understanding of the importance of
interactions between chemicals and social stressors in relation to health disparities. The goal is
to have 2 first-authored manuscripts, with one submitted and published prior to his applications
to residency programs following the completion of medical school. This will strengthen his
planned applications for research residency programs to further his research training.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Mount Sinai HHEAR Network Targeted Lab Hub
-
批准号:10875017
-
项目类别:
-
资助金额:$12.96万
-
财政年份:2023
-
负责人:Robert O Wright
-
依托单位:
Stress-Chemical Interactions and Neurobehavior in School Age Children
-
批准号:10337782
-
项目类别:
-
资助金额:$4.23万
-
财政年份:2021
-
负责人:Robert O Wright
-
依托单位:
The Programming Research in Obesity, GRowth, Environment and Social Stress (PROGRESS) Cohort
-
批准号:9761855
-
项目类别:
-
资助金额:$34.43万
-
财政年份:2017
-
负责人:Robert O Wright
-
依托单位:
ECHO Consortium on Perinatal Programming of Neurodevelopment
-
批准号:10675379
-
项目类别:
-
资助金额:$4.08万
-
财政年份:2016
-
负责人:Robert O Wright
-
依托单位:
ECHO Consortium on Perinatal Programming of Neurodevelopment
-
批准号:10018530
-
项目类别:
-
资助金额:$846.93万
-
财政年份:2016
-
负责人:Robert O Wright
-
依托单位:
ECHO Consortium on Perinatal Programming of Neurodevelopment
-
批准号:10239019
-
项目类别:
-
资助金额:$846.93万
-
财政年份:2016
-
负责人:Robert O Wright
-
依托单位:
Mount Sinai CHEAR Network Laboratory Hub
-
批准号:9351604
-
项目类别:
-
资助金额:$40.0万
-
财政年份:2016
-
负责人:Robert O Wright
-
依托单位:
ECHO Consortium on Perinatal Programming of Neurodevelopment
-
批准号:10469680
-
项目类别:
-
资助金额:$846.93万
-
财政年份:2016
-
负责人:Robert O Wright
-
依托单位:
ECHO Consortium on Perinatal Programming of Neurodevelopment
-
批准号:9355705
-
项目类别:
-
资助金额:$863.4万
-
财政年份:2016
-
负责人:Robert O Wright
-
依托单位:
Administrative Core
-
批准号:10660987
-
项目类别:
-
资助金额:$50.13万
-
财政年份:2015
-
负责人:Robert O Wright
-
依托单位:
Mount Sinai CHEAR Network Laboratory Hub Targeted Analysis Resource
-
批准号:9062195
-
项目类别:
-
资助金额:$634.57万
-
财政年份:2015
-
负责人:Robert O Wright
-
依托单位:
Mount Sinai HHEAR Network Targeted Lab Hub
-
批准号:10416034
-
项目类别:
-
资助金额:$230.0万
-
财政年份:2015
-
负责人:Robert O Wright
-
依托单位:
Mount Sinai CHEAR Laboratory Network Hub Administrative Core
-
批准号:9062193
-
项目类别:
-
资助金额:$52.0万
-
财政年份:2015
-
负责人:Robert O Wright
-
依托单位:
Targeted Analysis Resource
-
批准号:10660992
-
项目类别:
-
资助金额:$127.26万
-
财政年份:2015
-
负责人:Robert O Wright
-
依托单位:
Administrative Core
-
批准号:10416035
-
项目类别:
-
资助金额:$50.13万
-
财政年份:2015
-
负责人:Robert O Wright
-
依托单位:
Targeted Analysis Resource
-
批准号:10416037
-
项目类别:
-
资助金额:$127.26万
-
财政年份:2015
-
负责人:Robert O Wright
-
依托单位:
Mount Sinai HHEAR Network Targeted Lab Hub
-
批准号:9814353
-
项目类别:
-
资助金额:$130.0万
-
财政年份:2015
-
负责人:Robert O Wright
-
依托单位:
Mount Sinai HHEAR Network Targeted Lab Hub
-
批准号:10224490
-
项目类别:
-
资助金额:$100.0万
-
财政年份:2015
-
负责人:Robert O Wright
-
依托单位:
Mount Sinai CHEAR Network Laboratory Hub
-
批准号:9062192
-
项目类别:
-
资助金额:$1040.0万
-
财政年份:2015
-
负责人:Robert O Wright
-
依托单位:
Mount Sinai HHEAR Network Targeted Lab Hub
-
批准号:10660986
-
项目类别:
-
资助金额:$230.0万
-
财政年份:2015
-
负责人:Robert O Wright
-
依托单位:
国内基金
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