Cerebrovascular Fellowship Training Program

这种高度集中，竞争激烈的研究培训补助金（T-32）的续期申请旨在培养医生作为脑血管疾病和神经重症监护领域的独立临床科学家。我们目前的培训计划包括在NIH资助的，以T-2为重点的广泛转化研究中的临床研究和试验方面的广泛实践经验。我们的计划包括密切的指导，在计划的第一年内选择特定的研究项目，明确的课程工作，以及在急性中风和神经重症监护患者的评估和治疗方面的独特培训。我们的博士后培训计划已经培训了22年的神经科医生和16年的急诊医生，旨在培养脑血管疾病和神经重症监护领域的学术领导者和临床研究人员。在过去的15年里，我们的计划包括由这个T32资助。自T32启动以来，我们已经开发了一个非常强大的神经重症监护培训途径，我们已将其作为T32培训计划的一部分。这种创新和多学科的培训模式一直由NIH路线图和NIH资助的临床和转化科学与培训中心（CCTST）倡导。我们的培训计划由广泛的合作者和导师网络组成，这些合作者和导师已经在我们的毕业生中产生了学术生产力。培训借鉴了在急性卒中治疗和临床试验方法/管理、基因组学、出血性卒中、卒中和血管生理学的动物模型和体外模型、创伤性脑损伤、神经重症监护方法、神经流行病学、生物统计学、神经介入治疗方面具有专业知识的教师（血管内和外科）、神经影像学、神经恢复、神经超声学、神经技术开发、结局研究、卒中预防，研究的道德设计、遵守HIPAA和数据库管理。新的提交是对所追求的临床/转化卒中研究类型的额外关注;我们现在为那些打算追求设计和实施临床试验的人提供了途径，并为那些对流行病学/结果/遗传学途径感兴趣的人提供了单独的途径。在T32期间之前和期间接受过我们计划培训的个人迄今为止已经通过学术任命进行了生产，出版物和随后的奖金。这个相对罕见的T32项目专为从事临床研究的博士后医生科学家设计，是当今标准中风临床培训项目的重要和迫切需要的附加值。潜在的受训者必须完成神经病学或急诊医学的住院医师培训，并且必须证明对脑血管疾病和/或神经重症监护学术生涯的承诺;强调少数民族的招聘。我们正在请求每年最多四个博士后职位的持续支持（每年最多两名研究员，为期两年的培训支持）。

This highly focused, competitive renewal application for a Research Training Grant (T-32) is designed to develop physicians as independent clinical scientists in the area of cerebrovascular disease and neurocritical care. Our current training program includes extensive hands-on experience in clinical research and trials within a broad array of NIH-funded, T-2-focused, translational research. Our program includes close mentoring with selection of specific research projects within the first year of the program, well-defined course work, and unique training in the evaluation and treatment of patients with acute stroke and neurocritical care. Our post-doctoral training program has been training neurologists for 22 years and emergency physicians formally for 16 years with the goal of producing academic leaders and clinical researchers in the area of cerebrovascular disease and neurocritical care. The last 15 years of our program have included funding by this T32. Since the initiation of the T32, we have developed a very robust neurocritical care training pathway which we have included as part of this T32 training program. This innovative and multi-disciplinary training model has been advocated by the NIH roadmap and by the NIH-funded Centers for Clinical and Translational Science and Training (CCTST). Our training program is comprised of an extensive network of collaborators and mentors that has resulted in academic productivity among our graduates. Training draws on faculty with expertise in acute stroke therapy and clinical trial methodology/management, genomics, hemorrhagic stroke, animal models and in-vitro models of stroke and vascular physiology, traumatic brain injury, methods of neurocritical care, neuroepidemiology, biostatistics, neuro-interventional therapy (endovascular and surgical), neuroimaging, neurorecovery, neurosonology, neurotechnology development, outcome research, stroke prevention, ethical design of research, HIPAA compliance, and data-base management. New this submission is an additional level of focus on the type of clinical/translational stroke research pursued; we now have pathways for those that intend to pursue designing and implementing clinical trials, and a separate track for those interested in more of the epidemiology/outcomes/genetics path. Individuals trained in our program prior to and during the T32 period have been productive thus far as measured by academic appointments, publications, and subsequent grant awards. This relatively rare T32 program designed for post-doctoral physician scientists performing clinical research is significant and desperately needed value added to the standard stroke clinical training programs that exist today. Potential trainees must have completed a residency in neurology or emergency medicine and must demonstrate a commitment to an academic career in cerebrovascular disease and/or neurocritical care; minority recruitment is emphasized. We are requesting continuing support for up to four post-doctoral positions per year (maximum of two fellows per year for two years of training support).