Activated platelets as unique targets for early imaging and site-directed therapy of cardiovascular and inflammatory diseases

活化血小板作为心血管和炎症疾病早期成像和定点治疗的独特靶点

• 批准号: nhmrc : GNT1108670
• 负责人: Prof Karlheinz Peter
• 金额: $ 84.7万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/activated-platelets-unique-inflammatory-diseases/1346655
• 关键词: Activated; platelets; unique; targets; early

Heart attack and inflammatory diseases such as rheumatoid arthritis und multiple sclerosis either kill or severely disable people. We use the presence of platelets early on in these diseases to develop methods for early diagnosis as well as potential drugs for site-directed therapy. We have developed new biotechnological tools to perform novel high sensitivity imaging in Positron Emission Tomography (PET) and laser light imaging as well as a localised anti-inflammatory therapy.

心脏病发作和炎症性疾病，如类风湿性关节炎和多发性硬化症，要么杀死或严重残疾的人。我们利用这些疾病早期血小板的存在来开发早期诊断方法以及潜在的定点治疗药物。我们开发了新的生物技术工具，用于在正电子发射断层扫描（PET）和激光成像中进行新型高灵敏度成像以及局部抗炎治疗。