Targeting Activated Platelets: A novel innovative approach for the sensitive detection and therapeutic targeting of various cancers and their metastases

靶向活化血小板：一种新颖的创新方法，用于各种癌症及其转移的灵敏检测和治疗靶向

• 批准号: nhmrc : 1124670
• 负责人: Prof Karlheinz Peter
• 金额: $ 64.74万
• 依托单位: Baker IDI Heart and Diabetes Institute
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/targeting-activated-platelets-cancers-metastases/947401
• 关键词: Targeting; Activated; Platelets; novel; innovative

Early detection and selective therapy is critical for the survival of patients with cancer. We have shown in pilot experiments that platelets accumulate at the site of tumours and thus provide the opportunity to diagnose and localise cancer and its metastases. Based on this and also newly developed biotechnological tools we aim to develop multiple innovative imaging technologies. Furthermore, we will develop novel tumour-targeted and thus tumour site-specific, side-effect poor cancer treatments.

早期发现和选择性治疗对癌症患者的生存至关重要。我们已经在试点实验中表明，血小板在肿瘤部位聚集，从而提供了诊断和定位癌症及其转移的机会。基于此以及新开发的生物技术工具，我们旨在开发多种创新的成像技术。此外，我们将开发新型肿瘤靶向，从而肿瘤部位特异性，副作用少的癌症治疗方法。