Nanoparticle and virus assisted targeting of microRNA and DNA for the treatment of atherosclerosis, myocardial infarction and other inflammatory diseases
Nanoparticle and virus assisted targeting of microRNA and DNA for the treatment of atherosclerosis, myocardial infarction and other inflammatory diseases
批准号:
nhmrc : 1069492
负责人:
Prof Karlheinz Peter
金额:
$44.25万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2014
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2014-01-01 至 2017-12-31
中文摘要
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英文摘要
Inflammation is an underling cause or aggravating factor of many diseases, such as heart attack and atherosclerosis, but there is a lack of effective anti-inflammatory drugs that do not cause side effects. Using advanced biotechnology, we will use viruses and nanoparticles to selectively target gene therapeutics to areas of inflammation, resulting in high efficacy with low side effects. We will test these broadly usable therapeutics in mouse models of heart attack and atherosclerosis.
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Targeting Activated Platelets: A novel innovative approach for the sensitive detection and therapeutic targeting of various cancers and their metastases
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批准号:nhmrc : GNT1124670
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项目类别:Project Grants
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资助金额:$94.84万
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财政年份:2017
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负责人:Prof Karlheinz Peter
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依托单位:
Targeting Activated Platelets: A novel innovative approach for the sensitive detection and therapeutic targeting of various cancers and their metastases
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批准号:nhmrc : 1124670
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项目类别:Project Grants
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资助金额:$64.74万
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财政年份:2017
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负责人:Prof Karlheinz Peter
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依托单位:
Activated platelets as unique targets for early imaging and site-directed therapy of cardiovascular and inflammatory diseases
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批准号:nhmrc : 1108670
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项目类别:Project Grants
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资助金额:$58.03万
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财政年份:2016
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负责人:Prof Karlheinz Peter
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依托单位:
Activated platelets as unique targets for early imaging and site-directed therapy of cardiovascular and inflammatory diseases
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批准号:nhmrc : GNT1108670
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项目类别:Project Grants
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资助金额:$84.7万
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财政年份:2016
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负责人:Prof Karlheinz Peter
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依托单位:
Defining targets and establishing methods for prevention, diagnosis and therapy of inflammation, atherosclerosis and thrombosis
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批准号:nhmrc : 1079492
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项目类别:Research Fellowships
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资助金额:$56.51万
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财政年份:2015
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负责人:Prof Karlheinz Peter
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依托单位:
Defining targets and establishing methods for prevention, diagnosis and therapy of inflammation, atherosclerosis and thrombosis
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批准号:nhmrc : GNT1079492
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项目类别:Research Fellowships
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资助金额:$81.5万
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财政年份:2015
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负责人:Prof Karlheinz Peter
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依托单位:
Systems biology to identify molecular targets for vascular disease treatment (SysVasc), with a focus on atherosclerotic plaque instability
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批准号:nhmrc : 1102158
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项目类别:Targeted Calls
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资助金额:$31.34万
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财政年份:2015
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负责人:Prof Karlheinz Peter
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依托单位:
Systems biology to identify molecular targets for vascular disease treatment (SysVasc), with a focus on atherosclerotic plaque instability
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批准号:nhmrc : GNT1102158
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项目类别:International Collaborations
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资助金额:$45.07万
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财政年份:2015
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负责人:Prof Karlheinz Peter
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依托单位:
Defining "therapeutic" cells as well as establishing cell targeting and tracking technology for the treatment of myocardial infarction and atherosclerosis.
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批准号:nhmrc : 1070860
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项目类别:Project Grants
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资助金额:$44.32万
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财政年份:2014
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负责人:Prof Karlheinz Peter
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依托单位:
The role of C-reactive protein (CRP) in localising inflammation to misfolded proteins and “stressed” cells: A basis for the development of new anti-inflammatory reagents?
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批准号:nhmrc : 1067214
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项目类别:Project Grants
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资助金额:$48.24万
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财政年份:2014
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负责人:Prof Karlheinz Peter
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依托单位:
Developing functionalised microbubbles for molecular ultrasound imaging and targeted delivery of drugs and microRNA therapeutics
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批准号:nhmrc : 1050018
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项目类别:Project Grants
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资助金额:$45.16万
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财政年份:2013
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负责人:Prof Karlheinz Peter
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依托单位:
Defining targets and generating tools/therapeutic agents for prevention, diagnosis and therapy of atherothrombosis
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批准号:FT0992210
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项目类别:ARC Future Fellowships
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资助金额:$56.26万
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财政年份:2010
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负责人:Prof Karlheinz Peter
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依托单位:
Therapeutic targeting of CD40L-Mac-1 in inflammatory disease, in particular atherosclerosis
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批准号:nhmrc : 586653
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项目类别:NHMRC Project Grants
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资助金额:$37.32万
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财政年份:2010
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负责人:Prof Karlheinz Peter
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依托单位:
Research Fellowship
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批准号:nhmrc : 586652
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项目类别:NHMRC Research Fellowships
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资助金额:$10.08万
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财政年份:2010
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负责人:Prof Karlheinz Peter
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依托单位:
Platelet-Activating and Proinflammatory Effects of Proteins Secreted by Staphylococcus aureus
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批准号:nhmrc : 526626
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项目类别:NHMRC Project Grants
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资助金额:$34.41万
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财政年份:2009
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负责人:Prof Karlheinz Peter
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依托单位:
Novel single-chain antibody-targeted nanoparticles for diagnosis of vascular diseases in magnetic resonance imaging
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批准号:nhmrc : 472665
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项目类别:NHMRC Development Grants
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资助金额:$30.73万
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财政年份:2008
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负责人:Prof Karlheinz Peter
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依托单位:
Novel selective anti-platelet and clot-specific anticoagulant strategies targeting conformational states of GPIIb/IIIa
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批准号:nhmrc : 367645
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项目类别:NHMRC Project Grants
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资助金额:$33.11万
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财政年份:2006
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负责人:Prof Karlheinz Peter
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依托单位:
国内基金
海外基金
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