The role of C-reactive protein (CRP) in localising inflammation to misfolded proteins and “stressed” cells: A basis for the development of new anti-inflammatory reagents?
The role of C-reactive protein (CRP) in localising inflammation to misfolded proteins and “stressed” cells: A basis for the development of new anti-inflammatory reagents?
批准号:
nhmrc : 1067214
负责人:
Prof Karlheinz Peter
金额:
$48.24万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2014
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2014-01-01 至 2017-12-31
中文摘要
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英文摘要
Many diseases are exacerbated by inflammatory reactions. We describe how a protein circulating in the blood is a major driver of inflammatory reactions and how it is transformed from an inactive state to an active, highly pro-inflammatory state. Our project aims to understand how this transformation occurs at the molecular level, and to develop diagnostic techniques and innovative drugs to treat diseases such as heart attack, Alzheimer’s disease and other inflammatory diseases.
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Targeting Activated Platelets: A novel innovative approach for the sensitive detection and therapeutic targeting of various cancers and their metastases
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批准号:nhmrc : GNT1124670
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项目类别:Project Grants
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资助金额:$94.84万
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财政年份:2017
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负责人:Prof Karlheinz Peter
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依托单位:
Targeting Activated Platelets: A novel innovative approach for the sensitive detection and therapeutic targeting of various cancers and their metastases
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批准号:nhmrc : 1124670
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项目类别:Project Grants
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资助金额:$64.74万
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财政年份:2017
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负责人:Prof Karlheinz Peter
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依托单位:
Activated platelets as unique targets for early imaging and site-directed therapy of cardiovascular and inflammatory diseases
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批准号:nhmrc : 1108670
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项目类别:Project Grants
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资助金额:$58.03万
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财政年份:2016
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负责人:Prof Karlheinz Peter
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依托单位:
Activated platelets as unique targets for early imaging and site-directed therapy of cardiovascular and inflammatory diseases
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批准号:nhmrc : GNT1108670
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项目类别:Project Grants
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资助金额:$84.7万
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财政年份:2016
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负责人:Prof Karlheinz Peter
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依托单位:
Defining targets and establishing methods for prevention, diagnosis and therapy of inflammation, atherosclerosis and thrombosis
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批准号:nhmrc : 1079492
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项目类别:Research Fellowships
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资助金额:$56.51万
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财政年份:2015
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负责人:Prof Karlheinz Peter
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依托单位:
Defining targets and establishing methods for prevention, diagnosis and therapy of inflammation, atherosclerosis and thrombosis
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批准号:nhmrc : GNT1079492
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项目类别:Research Fellowships
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资助金额:$81.5万
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财政年份:2015
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负责人:Prof Karlheinz Peter
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依托单位:
Systems biology to identify molecular targets for vascular disease treatment (SysVasc), with a focus on atherosclerotic plaque instability
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批准号:nhmrc : 1102158
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项目类别:Targeted Calls
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资助金额:$31.34万
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财政年份:2015
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负责人:Prof Karlheinz Peter
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依托单位:
Systems biology to identify molecular targets for vascular disease treatment (SysVasc), with a focus on atherosclerotic plaque instability
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批准号:nhmrc : GNT1102158
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项目类别:International Collaborations
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资助金额:$45.07万
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财政年份:2015
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负责人:Prof Karlheinz Peter
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依托单位:
Nanoparticle and virus assisted targeting of microRNA and DNA for the treatment of atherosclerosis, myocardial infarction and other inflammatory diseases
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批准号:nhmrc : 1069492
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项目类别:Project Grants
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资助金额:$44.25万
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财政年份:2014
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负责人:Prof Karlheinz Peter
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依托单位:
Defining "therapeutic" cells as well as establishing cell targeting and tracking technology for the treatment of myocardial infarction and atherosclerosis.
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批准号:nhmrc : 1070860
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项目类别:Project Grants
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资助金额:$44.32万
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财政年份:2014
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负责人:Prof Karlheinz Peter
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依托单位:
Developing functionalised microbubbles for molecular ultrasound imaging and targeted delivery of drugs and microRNA therapeutics
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批准号:nhmrc : 1050018
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项目类别:Project Grants
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资助金额:$45.16万
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财政年份:2013
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负责人:Prof Karlheinz Peter
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依托单位:
Defining targets and generating tools/therapeutic agents for prevention, diagnosis and therapy of atherothrombosis
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批准号:FT0992210
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项目类别:ARC Future Fellowships
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资助金额:$56.26万
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财政年份:2010
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负责人:Prof Karlheinz Peter
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依托单位:
Therapeutic targeting of CD40L-Mac-1 in inflammatory disease, in particular atherosclerosis
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批准号:nhmrc : 586653
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项目类别:NHMRC Project Grants
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资助金额:$37.32万
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财政年份:2010
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负责人:Prof Karlheinz Peter
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依托单位:
Research Fellowship
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批准号:nhmrc : 586652
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项目类别:NHMRC Research Fellowships
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资助金额:$10.08万
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财政年份:2010
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负责人:Prof Karlheinz Peter
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依托单位:
Platelet-Activating and Proinflammatory Effects of Proteins Secreted by Staphylococcus aureus
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批准号:nhmrc : 526626
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项目类别:NHMRC Project Grants
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资助金额:$34.41万
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财政年份:2009
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负责人:Prof Karlheinz Peter
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依托单位:
Novel single-chain antibody-targeted nanoparticles for diagnosis of vascular diseases in magnetic resonance imaging
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批准号:nhmrc : 472665
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项目类别:NHMRC Development Grants
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资助金额:$30.73万
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财政年份:2008
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负责人:Prof Karlheinz Peter
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依托单位:
Novel selective anti-platelet and clot-specific anticoagulant strategies targeting conformational states of GPIIb/IIIa
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批准号:nhmrc : 367645
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项目类别:NHMRC Project Grants
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资助金额:$33.11万
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财政年份:2006
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负责人:Prof Karlheinz Peter
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依托单位:
国内基金
海外基金
含Re、Ru先进镍基单晶高温合金中TCP相成核—生长机理的原位动态研究
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批准号:52301178
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项目类别:青年科学基金项目
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资助金额:30.00万元
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批准年份:2023
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负责人:夏万顺
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依托单位:
Beclin1复合体在神经酰胺三己糖苷诱导Fabry病自噬障碍中的调控作用及机制研究
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批准号:81100840
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项目类别:青年科学基金项目
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资助金额:23.0万元
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批准年份:2011
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负责人:张巍
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依托单位:
抗单体C反应蛋白抗体在狼疮肾炎中参与补体调理与影响凋亡物质清除的机制研究
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批准号:81100497
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项目类别:青年科学基金项目
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资助金额:23.0万元
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批准年份:2011
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负责人:谭颖
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依托单位: