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Platelet-Activating and Proinflammatory Effects of Proteins Secreted by Staphylococcus aureus

Platelet-Activating and Proinflammatory Effects of Proteins Secreted by Staphylococcus aureus
金黄色葡萄球菌分泌的蛋白质的血小板激活和促炎作用
批准号：
nhmrc : 526626
负责人：
Prof Karlheinz Peter
金额：
$34.41万
依托单位：
Baker IDI Heart and Diabetes Institute
依托单位国家：
澳大利亚
项目类别：
NHMRC Project Grants
财政年份：
2009
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2009-01-01 至 2011-12-31
来源：
https://researchdata.edu.au/platelet-activating-proinflammatory-staphylococcus-aureus/100313
关键词：
PlateletActivatingProinflammatoryEffectsProteins

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中文摘要
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英文摘要
Skin or other Staphylococcus aureus (SA, golden Staph.) infections are common in Aboriginal Australians. We address the question whether atherosclerotic disease is accelerated by this bacterial infection. We will investigate whether a class of newly described toxins secreted by SA activates blood cells and leads to clot formation and potentially heart attack. We will evaluate plasma samples from cardiac patients and Aboriginal Austr. and will develop and test therapeutics in vitro and in mice.
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Targeting Activated Platelets: A novel innovative approach for the sensitive detection and therapeutic targeting of various cancers and their metastases
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  • 项目类别：
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Targeting Activated Platelets: A novel innovative approach for the sensitive detection and therapeutic targeting of various cancers and their metastases
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    nhmrc : 1124670
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Activated platelets as unique targets for early imaging and site-directed therapy of cardiovascular and inflammatory diseases
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    nhmrc : 1108670
  • 项目类别：
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    $58.03万
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  • 依托单位：
    Baker IDI Heart and Diabetes Institute
Activated platelets as unique targets for early imaging and site-directed therapy of cardiovascular and inflammatory diseases
  • 批准号：
    nhmrc : GNT1108670
  • 项目类别：
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  • 资助金额：
    $84.7万
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  • 负责人：
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  • 依托单位：
海外基金