San Diego Nathan Shock Center

项目概要-研发核心 SD-NSC研究发展核心（ResDev Core）将为以下人员的职业发展提供支持： 进入基础衰老生物学领域的初级研究人员，以及希望加入的资深研究人员 老龄化研究领域具体而言，ResDev Core将支持SD-NSC的科学目标， 通过促进职业生涯，加强对细胞异质性在衰老过程中作用的理解 以三种不同的方式发展老龄化研究人员：1）为感兴趣的项目提供种子资金 利用SD-NSC研究资源中心提供的独特科学服务， （衰老核心的人类细胞模型、衰老核心的异质性和衰老核心的整合模型），2）通过 提供三个研究资源所涵盖的科学服务的概念和实践培训 核心，以及3）通过在初级和高级成员之间建立个性化的指导计划， NSC网络和超越。ResDev核心将由Malene汉森博士、Sanford Burnham Prebys 医学发现研究所（SBP），谁带来了地方，国家和国际老龄化研究知识， 在指导初级科学家方面具有广泛的专业知识和高度的积极性。该方法将利用一个高度 综合和创新的方法，提供科学核心的概念和实践培训，沿着 在资助撰写和职业发展方面提供正式的指导。首先，将实施双轨试点赠款计划， 申请人申请资助核心使用和指导，或者直接从提交的 申请或通过赠款写作支持计划。第二，举办为期一天的讲习班， 科学核心将在一年一度的拉霍亚老龄会议的第二天举行，这是一个免费的为期一天的老龄化会议。 由圣地亚哥索尔克生物研究所（索尔克）的研究人员组织的研讨会 和SBP。该讲习班将以三个科学委员会提供的技术和分析为单元， 核心，沿着有关科学核心服务的潜在职业轨迹的信息。此外，一个关于 将提供赠款写作。第三，也是最后一点，将建立一个双轨个性化辅导方案， 这些初级研究人员将由资深研究人员指导， 或通过在国家安全委员会会议上形成的学员-导师配对关系，以及其他方式。

PROJECT SUMMARY – Research Development Core The SD-NSC Research Development Core (ResDev Core) will provide support for career development of junior researchers entering the field of basic aging biology, as well as established investigators who wish to join the field of aging research. Specifically, the ResDev Core will support the scientific goals of SD-NSC to enhance the understanding of the role of cell heterogeneity in the aging process by promoting career development of aging researchers in three different ways: 1) by providing seed funding for projects interested in taking advantage of the unique scientific services offered by the SD-NSC Research Resource Cores (Human Cell Models of Aging Core, Heterogeneity of Aging Core, and Integrative Models of Aging Core), 2) by providing conceptual and practical training in the scientific services covered by the three Research Resource Cores, and 3) by establishing a personalized mentoring program between junior and senior members of the NSC network and beyond. The ResDev Core will be led by Dr. Malene Hansen, Sanford Burnham Prebys Medical Discovery Institute (SBP), who brings local, national, and international aging research knowledge, and extensive expertise and high motivation in mentoring junior scientists. The approach will capitalize on a highly integrative and innovative approach by providing conceptual and practical training in the scientific Cores along with formalized mentoring in grant writing and career development. First, a two-track pilot grant program will be launched in which applicants apply for funding for Core usage and mentoring, either directly from submitted applications or via a grant-writing support program. Second, a one-day workshop to provide training in the scientific Cores will take place the day after the yearly La Jolla Aging Meeting, a free one-day aging symposium at the Salk Institute for Biological Studies (Salk) in San Diego organized by researchers at Salk and SBP. This workshop will feature modules on the techniques and analyses provided by the three scientific cores, along with information about potential career tracks in scientific Core services. In addition, a module on grant writing will be offered. Third and finally, a two-track personalized mentoring program will be established in which junior researchers will be mentored by established investigators, either as part of the pilot grant program or via pairing of mentee-mentor relationships formed at national NSC meetings, and beyond.