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Center for the Assessment of Tobacco Regulations (CAsToR) TCORS 3.0

烟草法规评估中心 (CAsToR) TCORS 3.0

基本信息

批准号：
10666144
负责人：
David Theodore Levy
金额：
$ 409.04万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-09-14 至 2028-08-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10666144
关键词：
Behavior Behavioral Behavioral Model Cardiovascular Diseases Characteristics Cigar Data Data Analyses Decision Making Education Electronic Nicotine Delivery Systems Electronic cigarette Ethnic Origin Family Smoking Prevention and Tobacco Control Act Flavoring Future Health Individual Infrastructure Manufacturer Marketing Meta-Analysis Modeling Monitor Nicotine Nicotine Dependence Outcome Pattern Policies Policy Analysis Policy Maker Population Population Assessment of Tobacco and Health Prevalence Process Public Health Race Regulation Research Research Personnel Respiratory Disease Risk Rural Population Sales Smoking Source Subgroup Surveys Tobacco Tobacco use Toxic effect Training Urban Population Vulnerable Populations Work Youth addiction behavioral health career comparative data modeling evidence base health warning insight longitudinal analysis models and simulation next generation novel polytobacco use population health public policy on tobacco response socioeconomics systematic review tobacco control tobacco products tobacco regulation tobacco regulatory science tool vaping young adult

项目摘要

CENTER Abstract The integrative theme for the Center for the Assessment of Tobacco Regulations (CAsToR) is to provide evidence-based and expert-informed modeling of the behavioral and public health impacts of FDA tobacco rules or other regulatory actions, focusing on Impact Analysis, Behavior and Health Effects as Scientific Domains. To evaluate the public health impacts of tobacco use and regulation, information must be gathered from different sources on tobacco use behaviors, health risks and the impact of regulations on use patterns. This information must then be synthetized and processed in a systematic and objective manner, helping policy makers gauge the impact that such regulations would have at the population level and aiding them in their decision-making process. Simulation modeling of tobacco use patterns and related health outcomes can serve as a key tool to assist FDA in evaluating and predicting population-level benefits and harms resulting from regulatory policies pertaining to new and existing tobacco products. When effectively applied, modeling also becomes a way of organizing and synthesizing different sources of information and identifying gaps in that information, especially where tobacco use patterns vary for different socio-economic populations. Our Center will have four projects based on the detailed analyses of current and historical tobacco use patterns in the US using established tobacco simulation models, with different approaches to provide a range of diverse insights. The overarching aim of Project 1 (Impact Analysis, Health Effects, and Behavior) is to conduct comparative modeling of the impact of FDA regulatory actions and novel tobacco products on tobacco use and long-term health outcomes. Project 2 (Addiction, Behavior, Impact Analysis, and Health Effects) will model the process of nicotine addiction among youths and young adults and its potential future consequences. Project 3 (Impact Analysis and Behavior) will develop tools to assess the impact of flavor restrictions on smoking and vaping for the overall US population and for urban and rural populations. Project 4 (Behavior, Health Effects, and Impact Analysis) will develop models for vulnerable populations and assess the impact of tobacco use and regulations by race/ethnicity, education, and their intersection. Four cores will serve the Center: the Administrative Core (AC) to coordinate the work of the projects and cores; the Career Enhancement Core (CEC) to provide training to junior investigators on the capabilities and limitations of tobacco regulatory science and simulation modeling; the Data Analysis and Modeling (DAM) Core to analyze and provide the data for each of the models and develop infrastructure for dissemination of model parameters and modeling results; and the Policy and Dissemination (PAD) Core to generate estimates for key policy and health effects, modeling parameters via systematic reviews, meta-analyses, and expert panels.

CENTER摘要烟草法规评估中心（CAsToR）的综合主题是提供 FDA烟草对行为和公共健康影响的循证和专家知情建模规则或其他监管行动，侧重于影响分析，行为和健康影响作为科学域.为了评估烟草使用和管制对公共健康的影响，必须收集信息，来自不同来源的关于烟草使用行为、健康风险和法规对使用模式的影响的报告。然后必须以系统和客观的方式综合和处理这些信息，制定者评估了这些法规在人口水平上的影响，并帮助他们决策过程烟草使用模式和相关健康结果的模拟模型可以作为一个关键工具，帮助FDA评估和预测人群水平的受益和危害，有关新的和现有烟草产品的监管政策。当有效应用时，建模还成为一种组织和综合不同信息来源并确定其中差距的方式烟草使用模式因不同社会经济群体而异。我们中心根据对美国当前和历史烟草使用模式的详细分析，使用已建立的烟草模拟模型，采用不同的方法提供一系列不同的见解。项目1（影响分析、健康影响和行为）的总体目标是进行比较 FDA监管行动和新型烟草产品对烟草使用和长期影响的建模健康成果。项目2（成瘾，行为，影响分析和健康影响）将模拟青少年和年轻人的尼古丁成瘾及其潜在的未来后果。项目3（影响分析和行为）将开发工具，以评估口味限制对吸烟和电子烟的影响，美国总人口以及城市和农村人口。项目4（行为、健康影响和影响分析）将为弱势群体制定模型，并评估烟草使用和法规的影响种族/民族，教育，以及它们的交叉点。四个核心将为中心服务：行政核心 (AC)协调项目和核心的工作;职业提升核心（CEC）提供培训向初级研究人员介绍烟草监管科学和模拟建模的能力和局限性; 数据分析和建模（DAM）核心，用于分析和提供每个模型的数据，发展传播模型参数和模型结果的基础设施;以及政策和传播（PAD）核心，用于生成关键政策和健康影响的估计数，通过系统性综述、荟萃分析和专家小组。

项目成果

期刊论文数量（129）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Parental Education, Household Income, and Cortical Surface Area among 9-10 Years Old Children: Minorities' Diminished Returns.

DOI：
10.3390/brainsci10120956
发表时间：
2020-12-09
期刊：
Brain sciences
影响因子：
3.3
作者：
Assari S
通讯作者：
Assari S

Exclusive and dual menthol/non-menthol cigarette use with ENDS among adults, 2013-2019.

2013 - 2019年成年人的独家和双薄荷醇/非门票香烟的使用。

DOI：
10.1016/j.pmedr.2021.101566
发表时间：
2021-12
期刊：
Preventive medicine reports
影响因子：
2.8
作者：
Usidame B;Hirschtick J;Zavala-Arciniega L;Mattingly DT;Patel A;Meza R;Levy DT;Fleischer NL
通讯作者：
Fleischer NL

The Potential Impact of Widespread Cessation Treatment for Smokers With Depression.

广泛停止治疗对抑郁症的吸烟者的潜在影响。