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Cancer Research Education, Advancement, Training and Empowerment (CREATE) in the Pacific

太平洋地区的癌症研究教育、进步、培训和赋权 (CREATE)

基本信息

批准号：
10663887
负责人：
Joseph Keawe'aimoku Kaholokula
金额：
$ 20.41万
依托单位：
UNIVERSITY OF HAWAII AT MANOA
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-08-01 至 2025-07-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10663887
关键词：
Address Behavioral Research Biochemical Biological Biological Assay Biological Products Biomedical Research Cancer Biology Cancer Burden Cancer Center Cancer Center Support Grant Cancer Control Characteristics Chinese Clinical Research Collaborations Colorectal Cancer Community Outreach Diagnosis Discipline Education Educational Activities Educational Curriculum Educational workshop Electronic Mail Environment Ethnic Origin Ethnic Population European European ancestry Faculty Filipino Filipino American Funding Future Goals Guam Hawaii High School Student Incidence Individual Interdisciplinary Study Invaded Island Japanese Japanese American Koreans Malignant Neoplasms Malignant neoplasm of liver Malignant neoplasm of lung Malignant neoplasm of pharynx Malignant neoplasm of prostate Malignant neoplasm of thyroid Mentors Mission NCI Center for Cancer Research Native Hawaiian Native-Born Natural Compound Natural Product Drug Natural Products Oral cavity Organism Oropharyngeal Pacific Islander Participant Patient Care Philanthropic Fund Physical environment Polynesian Population Population Sciences Prevention Preventive Process Professional Organizations Qualifying Research Research Personnel Research Training Resources Running Science Students Surveys System Talents Training Training Programs United States Universities anticancer research cancer health disparity cancer prevention cancer therapy career career development drug development drug discovery education planning education research eligible participant empowerment experience field study graduate student hands on research health disparity improved low socioeconomic status malignant breast neoplasm malignant stomach neoplasm medical schools member mortality multi-ethnic multidisciplinary next generation novel prevent programs recruit research faculty skills small molecule social media success summer internship summer research tumor initiation undergraduate student

项目摘要

This proposal will establish a training program called “Cancer Research Education, Advancement, Training and Empowerment” (CREATE) at the University of Hawai`i Cancer Center (UHCC). The program addresses the over-arching goal to enhance the training of a workforce to meet biomedical, behavioral, and clinical research needs to lower cancer incidence and mortality in the Pacific. CREATE takes advantage of the excellent research opportunities arising from the distinctive population and environment in Hawai`i and the Pacific with strong multi-disciplinary collaborations at the University of Hawai`i and its collaborations with the University of Guam. Research training in our multiethnic population with persons of Native Hawaiian, Pacific Islander, Japanese, Filipino, Chinese, Korean, and European ancestry is important to address cancer health disparities due to ethnicity and low socio-economic status while the unique biologic resources and natural compounds found nowhere else in the world will prepare the next generation of researchers for drug discovery and mechanistic cancer research to create new cancer treatments. Besides the 10-week hands-on experience at UHCC, CREATE will include a curriculum of multi-disciplinary seminars, workshops, and career development sessions. Success of the program will be evaluated through several indicators, e.g., proportion of participants in biomedical graduate programs and research careers, based on long-term tracking by surveys, email, social media, and personal contacts. The goal of CREATE to offer distinctive training experiences in cancer biology and in population sciences will be achieved through the implementation of the following aims: 1. Provide hands-on summer research experiences and a multi-disciplinary curriculum to undergraduate students residing in the Islands of Hawai`i and the Pacific to reinforce their intent to graduate with a science degree and to consider a career to address health disparities and contribute to drug discovery. 2. Offer first-year graduate students living in Hawai`i and the Pacific in cancer-related fields of study the opportunity to gain a 1-semester research experience in a multiethnic environment or unique cancer biology labs with the goal to enhance their skills to address causes, diagnosis, prevention, and treatment of cancer and to improve competitiveness in their future careers in cancer-related research. The program builds upon the many years of success of UHCC's Summer Internship Program that has provided research experiences to more than 220 students over the last 10 years and was previously funded by a CURE supplement to the P30 Cancer Center Support Grant and by philanthropic funds. The large pool of potential participants will represent the distinct ethnic composition of students from Hawai`i and Guam. In summary, CREATE will offer students in Hawai`i and the Pacific a unique research experience in population sciences or cancer biology that will enable them to pursue successful careers in cancer prevention and control.

该提案将建立一个名为“癌症研究教育、发展、培训”的培训项目，在夏威夷大学癌症中心（UHCC）进行的“创造和赋权”（CREATE）。该方案解决加强劳动力培训以满足生物医学，行为和临床需求的总体目标研究需要降低太平洋地区的癌症发病率和死亡率。CREATE利用了夏威夷独特的人口和环境所带来的极好的研究机会，太平洋与夏威夷大学的强有力的多学科合作及其与关岛大学。在我们的多民族人口与夏威夷原住民，太平洋人的研究培训岛民、日本人、菲律宾人、中国人、韩国人和欧洲人的血统对解决癌症健康问题很重要由于种族和社会经济地位低下而造成的差异，在世界其他地方找不到的化合物将为下一代研究人员提供药物发现和机械癌症研究创造新的癌症治疗方法。除了10周的实践之外在UHCC的经验，创建将包括多学科研讨会，讲习班和职业生涯的课程发展会议。该方案的成功将通过几个指标进行评估，例如，比例生物医学研究生课程和研究生涯的参与者，根据长期跟踪，调查、电子邮件、社交媒体和个人联系人。CREATE的目标是提供独特的培训癌症生物学和人口科学方面的经验将通过实施以下目标： 1.提供实践夏季研究经验和多学科课程，居住在夏威夷群岛和太平洋的本科生，以加强他们的意图，毕业于科学学位，并考虑职业生涯，以解决健康差距，有助于药物发现。 2.为居住在夏威夷和太平洋地区的一年级研究生提供与癌症相关的研究领域有机会获得一个学期的研究经验，在多民族的环境或独特的癌症生物学实验室的目标是提高他们的技能，以解决原因，诊断，预防和治疗癌症，并提高他们未来职业的竞争力，癌症相关的研究。该计划建立在UHCC暑期实习计划多年成功的基础上，在过去的10年里，为220多名学生提供了研究经验，由P30癌症中心支持补助金的CURE补充和慈善基金提供。大型游泳池潜在参与者的人数将代表夏威夷和关岛学生的独特族裔组成。在总之，CREATE将为夏威夷和太平洋地区的学生提供独特的人口研究经验。科学或癌症生物学，使他们能够在癌症预防方面取得成功，控制