J. NRSA Training Core

J.NRSA 培训核心

• 批准号: 10667311
• 负责人: WAYNE T. MCCORMACK
• 金额: $ 38.83万
• 依托单位: UNIVERSITY OF FLORIDA
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-15 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10667311
• 关键词: Assessment tool; Attitude; Career Choice; Clinic; Clinical Research; Collaborations; Communication; Community Health Education; Competence; Demography; Dentistry; Development; Discipline; Discipline of Nursing; Doctor of Philosophy; Educational process of instructing; Eligibility Determination; Ethics; Ethnic Origin; Exposure to; Funding; Gender; Graduate Education; Grant; Health; Health Occupations; Health Sciences; Institution; Interdisciplinary Study; Leadership; Matched Group; Medicine; Mentors; Methods; Modeling; National Research Service Awards; Outcome; Pharmacy facility; Phase; Positioning Attribute; Productivity; Public Health; Qualifying; Race; Research; Research Personnel; Research Training; Science; Self Efficacy; South Carolina; Students; TNFSF15 gene; Training; Training Programs; Translational Research; United States National Institutes of Health; Veterinary Medicine; Wisconsin; Writing; career; clinical implementation; college; comparison group; experience; innovation; interdisciplinary collaboration; interest; leadership development; novel; population health; pre-clinical research; pre-doctoral; programs; recruit; skills; success

The Team Science TL1 Program trains diverse doctoral and dual-degree-seeking students who aspire to careers in translational research. This innovative training model fully embraces team science, enabling TL1 Trainees to apply their developing disciplinary expertise in authentic interdisciplinary research experiences embedded in their PhD dissertation research, via applied team science training and funding of interdisciplinary TL1 Teams. We are uniquely positioned to expand this Team Training to produce investigators in all health- related professions experienced in translational team science, by pursuing the following objectives. Specific Aim 1. Build on the unique strength of the TL1 Team Training model and use a novel combination of quantitative and qualitative assessment methods based on a conceptual model of training progression and career success. Early results suggest positive changes in attitudes toward interdisciplinary collaboration and self-efficacy for clinical research. We will add other trainee comparison groups matched for race/ethnicity, gender, discipline, and research interests, on outcomes such as attitudes, self-efficacy, and research productivity, and we will develop and pilot a new competency-based assessment tool for CTS competencies. Specific Aim 2. Provide innovative and broad-based career and professional development opportunities to build professional skills in communication, teaching, mentoring, leadership, collaboration, research management, and grant-writing, and provide exposure to academic and nonacademic career pathways via Career Interest Teams. Specific Aim 3. Recruit and retain a critical mass of highly qualified TL1 trainees who are diverse with respect to demography, discipline, and translational research interests, and value the highest ethical standards in conducting translational team research. Additional emphasis will be placed on supporting TL1 Teams that include research in multiple phases, i.e., preclinical research, clinical research, clinical implementation, and/or population health. We will expand the Team Training model to the broader UF graduate education community. Specific Aim 4. Disseminate the TL1 Team Training model regionally and nationally via the CTSA Consortium by sharing the UF CTSI TL1 Team Training model (e.g., team science course, mentored team research strategy) with other institutions and CTSA hubs (including Mayo Clinic, Wisconsin, and South Carolina). Specific Aim 5. Support translational research training and academic leadership development beyond medicine and public health into the full spectrum of health science disciplines by the establishment of regional and/or national CTSA networks for dentistry, nursing, pharmacy, veterinary medicine, and other health professions. With a combination of NIH (10 positions) and institutional funds, this program will support four new TL1 teams per year, for two years each (16 trainees per year). Predoctoral PhD and dual-degree students pursuing health-related research in different colleges are eligible to apply and compete for funding as TL1 Teams.

Team Science TL1 项目培养多元化的博士生和双学位学生，他们渴望 从事转化研究的职业。这种创新的培训模式充分体现了团队科学，使 TL1 学员将他们不断发展的学科专业知识应用到真正的跨学科研究经验中 通过应用团队科学培训和跨学科资助，融入他们的博士论文研究 TL1 团队。我们拥有独特的优势，可以扩大这一团队培训，以培养所有健康领域的研究人员—— 通过追求以下目标，在转化团队科学方面经验丰富的相关专业人士。 具体目标 1. 以 TL1 团队培训模型的独特优势为基础，采用新颖的组合 基于培训进展概念模型的定量和定性评估方法 事业成功。早期结果表明对跨学科合作的态度发生了积极变化， 临床研究的自我效能感。我们将添加与种族/民族相匹配的其他受训者比较组， 性别、学科和研究兴趣，对态度、自我效能和研究等结果的影响 生产力，我们将开发并试行一种新的基于能力的 CTS 能力评估工具。 具体目标 2. 提供创新且基础广泛的职业和专业发展机会 培养沟通、教学、指导、领导、协作、研究方面的专业技能 管理和资助写作，并通过以下方式提供学术和非学术职业道路的机会 职业兴趣团队。 具体目标 3. 招募并留住足够数量的高素质 TL1 学员，他们要多元化并受到尊重 人口学、学科和转化研究兴趣，并重视最高道德标准 进行转化团队研究。我们将额外重点支持以下 TL1 团队： 包括多个阶段的研究，即临床前研究、临床研究、临床实施和/或 人口健康。我们将把团队培训模式扩展到更广泛的佛罗里达大学研究生教育社区。 具体目标 4. 通过 CTSA 联盟在地区和全国范围内传播 TL1 团队培训模型 通过分享 UF CTSI TL1 团队培训模型（例如团队科学课程、指导团队研究 战略）与其他机构和 CTSA 中心（包括梅奥诊所、​​威斯康星州和南卡罗来纳州）。 具体目标 5. 支持医学以外的转化研究培训和学术领导力发展 通过建立区域和/或 牙科、护理、药学、兽医和其他卫生专业的国家 CTSA 网络。 通过 NIH（10 个职位）和机构资金的结合，该计划将支持四个新的 TL1 团队 每年，每两年（每年 16 名学员）。博士前博士生和双学位学生 不同学院的健康相关研究都有资格以 TL1 团队的身份申请和竞争资助。

项目成果

Experimental and Computational Models of Transport of Galectin-3 Through Glycosylated Matrix.

• DOI: 10.1007/s10439-022-02949-6
• 发表时间: 2022-06
• 期刊: ANNALS OF BIOMEDICAL ENGINEERING
• 影响因子: 3.8
• 作者: Pineiro-Llanes, Janny;Rodriguez, Camille D.;Farhadi, Shaheen A.;Hudalla, Gregory A.;Sarntinoranont, Malisa;Simmons, Chelsey S.
• 通讯作者: Simmons, Chelsey S.

Assessment of Scanning Mobility Particle Sizer (SMPS) for online monitoring of delivered dose in an in vitro aerosol exposure system.

• DOI: 10.1016/j.tiv.2023.105650
• 发表时间: 2023-07
• 期刊: Toxicology in vitro : an international journal published in association with BIBRA
• 作者: S. N. Shankar;Kiran Mital;Eric Le;Gregory S. Lewis;Arantzazu-Eiguren Fernandez;T. Sabo-Attwood;Chang-Yu Wu

Current Practice and the Future of Deep Brain Stimulation Therapy in Parkinson's Disease.

• DOI: 10.1055/s-0037-1601893
• 发表时间: 2017-04
• 期刊: Seminars in neurology
• 影响因子: 2.7
• 作者: Almeida L;Deeb W;Spears C;Opri E;Molina R;Martinez-Ramirez D;Gunduz A;Hess CW;Okun MS
• 通讯作者: Okun MS

Emerging therapies in Parkinson disease - repurposed drugs and new approaches.

• DOI: 10.1038/s41582-019-0155-7
• 发表时间: 2019-04
• 期刊: Nature reviews. Neurology
• 作者: Elkouzi A;Vedam-Mai V;Eisinger RS;Okun MS
• 通讯作者: Okun MS

Brain Monoamine Dysfunction in Response to Predator Scent Stress Accompanies Stress-Susceptibility in Female Rats.

• DOI: 10.3390/biom13071055
• 发表时间: 2023-06-29
• 期刊: Biomolecules
• 影响因子: 5.5