Harnessing the power of text messaging to reduce HIV incidence in adolescent males across the United States

利用短信的力量降低美国青少年男性的艾滋病毒发病率

• 批准号: 10703231
• 负责人: Michele L. Ybarra
• 金额: $ 215.47万
• 依托单位: CENTER FOR INNOVATIVE PUBLIC HEALTH RESEARCH
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-23 至 2026-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10703231
• 关键词: 18 year old; 20 year old; AIDS prevention; Adolescent; Adoption; Advertisements; Advisory Committees; Affect; African American; Attitude; Black race; Complex; Counseling; Country; Data; Development; Disparate; Disparity; Enrollment; Ensure; Epidemiology; Face; Focus Groups; HIV; HIV Infections; HIV Seronegativity; Health Status; Hispanic; Human immunodeficiency virus test; Incidence; Intervention; Latino; Latinx; Male Adolescents; Mental Health; Methods; Monitor; Motivation; Outcome Measure; Participant; Patient Self-Report; Population; Population Heterogeneity; Prevention; Prevention program; Preventive service; Program Accessibility; Protocols documentation; Public Health; Race; Research; Risk; Rural; Safety; Sampling; Services; Technology; Teenagers; Test Result; Testing; Text Messaging; United States; Youth; age group; behavior change; cisgender; cost; ethnic minority; healthy sexuality; home test; innovation; male; men; minority children; novel; pre-exposure prophylaxis; programs; racial minority; recruit; response; rural area; rural setting; secondary outcome; sexual minority; sexual minority boys; sexual minority group; sexual minority male; sexual minority youth; sexually active; social; social media; sociodemographics; uptake

Sexual minority male youth face disparate risk for HIV acquisition. Disparities are even starker for African American/Black and Hispanic sexual minority male youth, who account for 51% and 25% of new HIV infections, respectively. Youth living in southern states and in rural settings also face elevated risk for HIV acquisition. As such, access to HIV testing and counseling remains a critical component of prevention, and effectively extending these services to sexual minority male youth is a priority. The wide adoption of text messaging provides novel opportunities to go where youth “are” across socio- demographically different groups, and overcomes structural challenges of traditional interventions. Moreover, being able to access sensitive content when and where one chooses facilitates safe spaces for youth to engage with the content, which is important for those who are not ‘out’. Importantly too, reviews suggest that programs delivered via text messaging can affect complex behavior change, including HIV testing among sexual minority adolescent boys. Thus, we have the opportunity to utilize the power and reach that text messaging affords to deliver an HIV prevention program across the country to a diverse population of youth. To this end, we propose to test the impact of #GrowingUpGuy (#GUY) on new HIV infections among 13-20 year-old sexual minority male youth across the United States. #GUY will be an adaptation of the research team’s previous text messaging-based HIV prevention/healthy sexuality programs developed at the national level for sexual minority youth. Given the epidemiology of HIV infections in the United States, we plan to target youth 13-20 years of age. Because of the lack of accessible programs for younger youth, our recruitment effort will place an emphasis on those 18 years of age and younger. Sample diversity will be ensured using recruitment targets and a complex enrollment strategy that we have developed and refined over our intervention endeavors such that half will self-identify as Black/African American, Latino, and/or of mixed race; and at least 20% will be living in a rural area or southern state. Specifically, we aim to: Specific Aim 1: Finalize the GrowingUpGuy (#GUY) intervention and protocol for sexually active, HIV negative, cisgender, sexual minority boys and men up to 20 years of age across the United States. Specific Aim 1a. Adapt previous intervention content to create GrowingUpGuy (#GUY), a salient, technologically delivered HIV prevention program. Specific Aim 1b: Finalize the intervention protocol, including confirmation of HIV test results. Specific Aim 2: Test the #GUY intervention for impact on HIV incidence (n=5,000). Our main outcome measures will be: 1) OraQuick-confirmed HIV incidence; and self-reported 2) PrEP and PEP use, 3) HIV status, and 4) number of STIs. Secondary outcomes include: 1) information about and 2) motivation for uptake of PrEP; and 3) the impact of the intervention on mental health indicators.

性少数男性青年面临着不同的艾滋病毒感染风险。差距甚至更加明显 非裔美国人/黑人和西班牙裔性少数男性青年，分别占新增艾滋病毒感染者的 51% 和 25% 分别感染。生活在南部各州和农村地区的青少年也面临着较高的艾滋病毒风险 获得。因此，获得艾滋病毒检测和咨询仍然是预防的一个重要组成部分， 有效地将这些服务扩展到性少数男性青年是一个优先事项。 短信的广泛采用提供了新的机会，让他们可以跨社会群体去往年轻人“所在”的地方。 人口结构不同的群体，并克服了传统干预措施的结构性挑战。而且， 能够在选择的时间和地点访问敏感内容，为青少年提供安全的空间 参与内容，这对于那些还没有“出局”的人来说很重要。同样重要的是，评论表明 通过短信提供的计划可以影响复杂的行为改变，包括艾滋病毒检测 性少数的青春期男孩。因此，我们有机会利用这种力量并达到该文本 信息传递有助于在全国范围内向不同的青年群体提供艾滋病毒预防计划。 为此，我们建议测试 #GrowingUpGuy (#GUY) 对新发 HIV 感染的影响 美国各地 13-20 岁的性少数男性青年。 #GUY 将改编自 研究小组之前开发的基于短信的艾滋病毒预防/健康性行为项目 国家层面的性少数青少年。鉴于美国艾滋病毒感染的流行病学，我们计划 目标人群为13-20岁青少年。由于缺乏适合年轻一代的无障碍项目，我们的 招聘工作将重点关注 18 岁及以下的人。样本多样性将是 确保使用我们制定和完善的招聘目标和复杂的招生策略 我们的干预努力使一半人自我认同为黑人/非裔美国人、拉丁裔和/或混血儿 种族;至少 20% 将居住在农村地区或南部各州。具体来说，我们的目标是： 具体目标 1：最终确定 GrowingUpGuy (#GUY) 对性活跃、 美国各地 20 岁以下的 HIV 阴性、顺性别、性少数男孩和男性。 具体目标 1a。改编之前的干预内容来创建 GrowingUpGuy (#GUY)，一个突出的、 技术实施的艾滋病毒预防计划。 具体目标 1b：最终确定干预方案，包括确认 HIV 检测结果。 具体目标 2：测试#GUY 干预措施对艾滋病毒发病率的影响（n=5,000）。我们的主要 结果衡量标准将是： 1) OraQuick 确认的艾滋病毒发病率；和自我报告 2) PrEP 和 PEP 使用，3) HIV 状况，以及 4) STI 数量。次要结果包括：1) 相关信息和 2) 动机 PrEP 的吸收； 3）干预对心理健康指标的影响。