Core 3-Biostatistics

核心3-生物统计学

• 批准号: 10683945
• 负责人: J. Jack LEE
• 金额: $ 26.12万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-16 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10683945
• 关键词: Address; Adopted; Algorithms; Animal Model; Award; Bioconductor; Bioinformatics; Biological Markers; Biometry; Cancer Center; Cell Line; Clinical; Clinical Data; Clinical Research; Clinical Trials; Clinical Trials Design; Code; Collaborations; Complex; Computer Analysis; Conduct Clinical Trials; Confidentiality of Patient Information; Data; Data Analyses; Databases; Development; Ensure; Epidemiology; Experimental Designs; Genomics; Human Resources; Immunologics; Laboratories; Libraries; Link; Manuscripts; Methods; Pathology; Patients; Phase; Play; Proteomics; Publications; Reporting; Research; Research Personnel; Research Project Grants; Resources; Role; Services; Statistical Data Interpretation; Statistical Methods; Structure; Technology; University of Texas M D Anderson Cancer Center; Writing; bioinformatics resource; biomarker discovery; career; clinical database; data management; design; experimental study; genome analysis; genomic data; high dimensionality; innovation; laboratory experiment; meetings; melanoma; member; novel; open source; pre-clinical; predictive marker; programs; sound; tissue resource; tool; translational study; trial design; web-accessible

Core 3: Project Summary/Abstract The Biostatistics and Bioinformatics Core 3 provides comprehensive service to guide design of experiments, to optimize quantitative data analysis, and to maintain statistical justification and interpretation of results. Specifically, Core 3 will implement sound experimental design principles that are tailored to address specific scientific questions for each project. Core 3 will also carry out data analyses using suitable statistical methods and bioinformatics algorithms, and will contribute to the interpretation of results through written reports and frequent interactions with project investigators. Whenever appropriate, Core 3 will develop new analysis tools to address new challenges in the analysis of various data, especially high-throughput genomic and proteomic data. Members of Core 3 will participate in monthly SPORE meetings with all project investigators, ensuring that statistical and data analysis/management issues are carefully considered during all phases of each SPORE experiment. Thus, from inception to reporting and publication, basic laboratory and translational experiments will benefit from the SPORE program that will be used to augment existing MD Anderson Cancer Center biostatistics resources.

核心3：项目总结/摘要 生物统计学和生物信息学核心3提供全面的服务，以指导设计 实验，以优化定量数据分析，并保持统计理由和解释 结果具体来说，核心3将实施合理的实验设计原则， 每个项目的具体科学问题。核心3还将使用适当的统计方法进行数据分析， 方法和生物信息学算法，并将有助于通过书面解释结果 报告和与项目调查人员的频繁互动。在适当的时候，核心3将开发新的 分析工具，以应对各种数据分析中的新挑战，特别是高通量基因组 和蛋白质组学数据。Core 3的成员将参加每月的SPORE会议， 调查员，确保在调查期间认真考虑统计和数据分析/管理问题， 每个孢子实验的所有阶段。因此，从开始到报告和出版，基础实验室 而转化实验将从SPORE计划中受益，该计划将用于增强现有的MD 安德森癌症中心生物统计学资源。