NATIONAL NEUROLOGICAL AIDS BANK

项目摘要/摘要 在研究中需要人脑组织来了解艾滋病毒和共病情况的影响 例如中枢神经系统的阿片类药物使用障碍。自1998年以来，国家神经艾滋病银行(NNAB)已经 从艾滋病毒血清阳性(HIV)参与者的队列中收集脑组织和数据。这样做的目的是 行政补充是继续NNAB正在进行的工作，在我们的免费时间延长资金 预计用完(预计2023年6月1日)，在审查和谈判合同之前(预计 2023年8月下旬。这些资金将用于支付调查人员/工作人员的工资、用品、纸巾费用等。 获取、处理、存储组织并将其运送给经批准的研究人员。然后我们的样本和数据就可以 继续通过我们的分配程序提供给调查人员，直到合同获得批准。

Project Summary/Abstract There is a need for human brain tissues in research to understand the impact HIV and co-morbid conditions such as opioid use disorders on the CNS. Since 1998, the National Neurological AIDS Bank (NNAB) has collected brain tissues and data from a cohort of HIV-seropositive (HIV+) participants. The purpose of this administrative supplement is to continue the ongoing work of NNAB after our no-cost time extension funds are expected to run out (estimated June 1, 2023) and before the contract is reviewed and negotiated (estimated late August, 2023. The funds will pay such costs as salary of investigators/staff, supplies, costs of tissue acquisition, processing, storage, and to ship tissue to approved researchers. Our samples and data can then continue to be available to investigators through our allocations process until the contracts are approved.