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NATIONAL NEUROLOGICAL AIDS BANK

国家神经艾滋病银行

基本信息

批准号：
10818276
负责人：
ELYSE J SINGER
金额：
$ 42.75万
依托单位：
UNIVERSITY OF CALIFORNIA LOS ANGELES
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-06-13 至 2024-02-29
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10818276
关键词：
Acquired Immunodeficiency Syndrome Address Administrative Supplement Affect Aging Autopsy Blood Blood specimen Brain Cerebrospinal Fluid Cognitive Collaborations Contracts Contracts Review Data Data Coordinating Center Disease Drug usage Event Funding Grant Guidelines HIV HIV Seropositivity Human Informed Consent Investigation Longitudinal cohort Maintenance Measures Mediation Motor National NeuroAids Tissue Consortium Nervous System Neurologic Neuropathogenesis Neuropsychology Participant Procedures Process Protocols documentation Research Research Personnel Resources Role Running Sampling Services Shapes Shipping Standardization Time Tissue Banks Tissue Sample Tissues United States National Institutes of Health Urine Wages Work brain tissue central database cohort comorbidity cost data repository data resource drug misuse human tissue instrument neuroAIDS operation opioid use disorder parent grant psychologic quality assurance recruit tissue processing tissue resource tool

项目摘要

Project Summary/Abstract There is a need for human brain tissues in research to understand the impact HIV and co-morbid conditions such as opioid use disorders on the CNS. Since 1998, the National Neurological AIDS Bank (NNAB) has collected brain tissues and data from a cohort of HIV-seropositive (HIV+) participants. The purpose of this administrative supplement is to continue the ongoing work of NNAB after our no-cost time extension funds are expected to run out (estimated June 1, 2023) and before the contract is reviewed and negotiated (estimated late August, 2023. The funds will pay such costs as salary of investigators/staff, supplies, costs of tissue acquisition, processing, storage, and to ship tissue to approved researchers. Our samples and data can then continue to be available to investigators through our allocations process until the contracts are approved.

项目总结/摘要有必要对人脑组织进行研究，以了解艾滋病毒和共病状况的影响例如中枢神经系统的阿片类药物使用障碍。自1998年以来，国家神经艾滋病银行（NNAB）从一组HIV血清阳性（HIV+）参与者中收集脑组织和数据。这样做的目的行政补充是继续NNAB正在进行的工作后，我们的无成本时间延长资金是预计将用完（估计2023年6月1日），并在合同审查和谈判之前（估计 2023年8月下旬这些资金将用于支付研究者/工作人员的工资、用品、组织费用等费用采集、处理、储存和运送组织给经批准的研究人员。我们的样本和数据可以继续通过我们的分配程序向调查人员提供，直到合同获得批准。

项目成果

期刊论文数量（49）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Orientation and Training of New Biobank Personnel.

新生物库人员的定位和培训。

DOI：
10.1007/978-1-4939-8935-5_6
发表时间：
2019
期刊：
Methods in molecular biology (Clifton, N.J.)
影响因子：
0
作者：
Williams,RyanR;Gupta,Diviya;Yong,WilliamH
通讯作者：
Yong,WilliamH

Abstracts of the American College of Neuropsychopharmacology (ACNP) 53rd Annual Meeting, December 7-11, 2014, Phoenix, Arizona.

美国神经精神药理学学会 (ACNP) 第 53 届年会摘要，2014 年 12 月 7-11 日，亚利桑那州凤凰城。

DOI：
10.1038/npp.2014.279
发表时间：
2014
期刊：
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
影响因子：
0
作者：
通讯作者：

The role of host genetics in the susceptibility for HIV-associated neurocognitive disorders.

宿主遗传学在 HIV 相关神经认知障碍易感性中的作用。

DOI：
10.1007/s10461-008-9360-x
发表时间：
2009
期刊：
AIDS and behavior
影响因子：
4.4
作者：
Levine,AndrewJ;Singer,ElyseJ;Shapshak,Paul
通讯作者：
Shapshak,Paul

A review of room temperature storage of biospecimen tissue and nucleic acids for anatomic pathology laboratories and biorepositories.

DOI：
10.1016/j.clinbiochem.2013.12.011
发表时间：
2014-03
期刊：
Clinical biochemistry
影响因子：
2.8
作者：
Lou JJ;Mirsadraei L;Sanchez DE;Wilson RW;Shabihkhani M;Lucey GM;Wei B;Singer EJ;Mareninov S;Yong WH
通讯作者：
Yong WH

Procurement, Storage, and Use of Blood in Biobanks.