Enhancing dissemination and career development in sex and gender translational science in alcohol use

工程摘要 在过去十年中，妇女饮酒的情况大幅度增加，令人关切， 男性的增幅较小。虽然饮酒与男女的重大健康风险密切相关， 与男性相比，女性与酒精有关的健康后果更为严重。加上这个 问题，酒精使用的治疗开发没有考虑，也没有对已知的性别差异做出反应， 饮酒由于这些原因，该领域需要提高进行转化科学的能力， 研究与饮酒有关的性别差异。这份R13提案是一份为一项双边- 在酒精问题研究学会所在地举行的年度（每两年一次）、为期一天的卫星会议 会议将重点关注酒精使用中的性别和性别差异的转化创新。本次会议 将提供几个关键功能：1）作为一个国际科学家，临床医生和 * 培训人员支持交流思想，并促进在性/性别和酗酒问题上的新合作 从T1到T4的翻译。2)促进下一代转化酒精的发展 研究人员，通过支持25个旅行奖，研究生，博士后研究员，和早期职业生涯的初级 教师介绍他们的研究。3)提供关于最佳做法程序和定义的信息， 与性/性别和酒精研究相关的参数。一个互动的节目将包括两个主要的 国际演讲者和学员，最大限度地提高多样性和包容性。R13计划将提供 独特的贡献NIAAA的使命纳入性和性别“的设计，分析，和科学的 报告其资助的研究。这是确保每个人，无论性别或 性别、从酒精研究进展中获益“32.

Project Abstract Alcohol use among women has substantially and concerningly increased over the last decade, relative to smaller increases among men. While drinking is strongly associated with significant health risks in both sexes, females have exacerbated alcohol-related health consequences when compared to males. Compounding this issue, treatment development for alcohol use has not considered, nor is responsive to known sex differences in alcohol use. For these reasons, the field requires an increased capacity to conduct translational science to study sex and gender differences in relation to alcohol use. This R13 proposal is a request for funding for a bi- annual (once every two years), one-day satellite meeting held at the site of the Research Society on Alcohol conference to focus on translational innovations in sex and gender differences in alcohol use. This meeting would serve several key functions: 1) To serve as a hub for an international group of scientists, clinicians, and trainees to support the exchange of ideas and promote new collaborations on sex/gender and alcohol use spanning T1 to T4 translation. 2) To foster the development of the next generation of translational alcohol researchers, by supporting 25 travel awards to graduate students, postdoctoral fellows, and early-career junior faculty to present their research. 3) To provide information on best practice procedures and definitional parameters relevant to the study of sex/gender and alcohol. An interactive program would feature both leading international speakers and trainees, maximizing diversity and inclusion. This proposed R13 grant will provide a unique contribution to NIAAA’s mission to incorporate sex and gender “into the design, analysis, and scientific reporting of the studies it funds. This is a critical step toward ensuring that everyone, regardless of sex or gender, benefits from alcohol research advances”32.